Final Flashcards
UTI - Risk Factors
Age
Immobility
Instrumentation and urinary catheterization
Atonic bladder (spinal cord)
Increased sexual activity
Spermicide associated in use with diaphragm
Uncircumcised penis
Obstruction (Renal calculi, Prostatic Hyperplasia, Malformations or urinary tract abnormalities)
Constipation
Women is greater than men (Anatomic variations, Surgical or natural menopause without hormone replacement therapy, Pregnancy)
Kidney transplantation
Diabetes Mellitus
Partners of Viagra
STDs
UTI - Pathogenesis
Most common route: Urethra -> Bladder
Upper or Lower Urinary Tract Infection
Blood borne
Fecal associated gram negative (E. coli – 80%, Staphylococcus – 5-15%)
Acquired via lymphatic system
Prevention: Intermittent/condom catheter
Urinary Incontinence - Definition
loss of bladder control or being unable to control urination
Stress Incontinence
Physical exertion-bending, sneezing, coughing ->
Increase intrabdominal pressure ->
Weakness of PFM (external urethral sphincter) and failure of internal urethral sphincter (IUS)
Urge Incontinence (Overactive incontinence)
Sudden desire
Detrusor instability – not fully understood
Triggers: Running water, anxiety, arrival at home
At what age does incontinence typically occur?
> 60 years
Normal characteristics of urine
Color: Yellow-Amber
Urochome – waste product during protein metabolism
Voiding: 3-5 hours and in elderly 2 hours
Abnormal characteristics of urine
Negative: Glucose, Ketones, Blood, Protein, Bilirubin, RBC, WBC
Pyelonephritis
Bacteria ascending from bladder to kidney
Cause: Vesicoureteral reflux (Backflow of urine into the kidneys)
Clinical Manifestations: Abrupt, Murphy’s Sign (punch costal-vertebral angle)
Renal Cell Carinoma
Tumor in kidneys
Palpable abdominal mass
Hematuria – 50%
Wilms Tumor (nephroblastoma)
Most common in children
Malignant
Clinical manifestations: abdominal mass
Renal Calculi - Nephrolithiasis
Acute “Colicky” pain – flank pain radiates to groin or perineal area (scrotum in males and labia in female) with hematuria
Severe pain – no comfortable position
(stones)
Renal Cystic Diseases
Cyst with fluid or tubular elements (semi solid) ->
Degeneration of renal tissue ->
Obstruction of urine flow
Polycystic Kidney Disease (PKD)
Significantly enlarged kidneys (palpable abdominal mass)
What is Chronic Kidney Disease?
Progressive loss -> End Stage Renal Disease (ESRD) -> Require dialysis or transplant
CKD - Pathogenesis
Release of angiotensin leads to VC
Reduce surface area for filtration -> Reduced Glomerular Filtration Rate (GFR)
Afferent, filtration system , bowman space, proximal tubule, into distal convulant tubule leads to excretion.
CKD - Stages w/values
G1: Normal GFR** (> or = 90mL/min) but other signs and symptoms indicating kidney disease **
G2: Kidney damage with midly decreased GFR (60-89 mL/min)
G3a: Mildly to Moderately decreased GFR (45-59 mL.min)
G3b: Moderately to Severely decreased GFR (30-44 mL/min)
G4: Severely decreased (15-29 mL/min) **Systemic damage **
G5: Kidney failure (ESRD, GFR ,15 mL/min) Systemic damage
Stage G1
Blood Urea Nitrogen (BUN) and Creatinine – typically normal
Stage 1 – reversible (DM), remain indefinitely, some progress
BUN and Creatinine
If kidney is damaged -> Urea retention is high in blood (BUN)
Creatine provides energy to muscles and forms Creatinine (byproduct)
Creatinine travels in blood and excreted in urine
Stage G2
Damage capillaries – leak albumin in urine
Can remain here if proper control of HTN and blood glucose
Stage G3a-b:
More noticeable albumin in urine than blood -> Azotemia
Azotemia: increased BUN and Creatinine (Fever, nausea, etc.)
Stage G4
Kidney not able to function
Proteinuria (albuminuria): Excess amounts of urine
Increased BUN and Creatinine
Increased renin -> hypertensive -> progress to stage 5
(Renin being made causes VC leads to HTN)
Stage G5
Failed kidney often needs multiple dialysis and transplant
Uremia – nausea, vomiting, anorexia, lethargy, pruritis (itching), sensory/motor neuropathy, pericarditis, impaired heart function, asterixis, seizures
Kidney cannot excrete toxins
Not able to maintain pH, fluid, electrolyte
Implications of PT - Kidney Disease
Aware of early signs and symptoms
Always ask: Hematuria, unexplained weight loss
Constitutional Symptoms (aka red flags)
Unexplained or insidious onset of back pain, flank or shoulder pain
New onset of mental state changes or increased confusion – delirum or confusion
Appropriate catheter care – obubstructed flow
(Do not hang the urine collection bag above the level of the bladder, never allow kinking, do not rest it on the floor)
Sternal pain or mass – most common due to metastasis to sternum
HTN – due to obstruction (VC increased leads to this)
Risk for UTI
Increased risk for cerebral and aortic aneurysm (weakening of blood vessels)
Risk for mitral valve problems (more fluid in blood leads to more strain)
Intermittent and sometimes not severe colicky pain
Unilateral back pain – thoracolumbar junction to illiac crest
Murphy’s sign (palpation)
- Treat or refer?
–Refer but screen for more information