Final Flashcards

1
Q

When can cell free fetal dna testing be done

A

10-14 weeks until delivery

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2
Q

What is PAPP-P HCG testing

A

PAPP-A is a glycoprotein produced by the placenta and the decidua

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3
Q

What does a low PAPP-A score indicate?

A

Low PAPP-A may be associated with: A lower birth weight baby as it might indicate that your placenta may not be working as well as it should. An increased chance of having an early birth

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4
Q

During what weeks of pregnancy is a PAPP-A and hCG screening done

A

this test is performed between 10-14 weeks

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5
Q

During what weeks is the U/S Nuchal translucency test done?

A

10-14 weeks

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6
Q

When is the fetal anatomy scan completed during what weeks of gestation?

A

A fetal anatomy scan is done between 15-23 weeks

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7
Q

during what trimester is the quad screen done

A

the quad screen is done during the 2nd trimester but can be done up to 22 weeks

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8
Q

What is a quad screen? What four substances does it measure in maternal blood?

A

Alpha-fetoprotein (AFP), a protein made by the developing baby
Human chorionic gonadotropin (HCG), a hormone made by the placenta
Estriol, a hormone made by the placenta and the baby’s liver
Inhibin A, another hormone made by the placenta

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9
Q

What is integrative screening?

A

integrative screening combines first and 2nd trimester screening

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10
Q

When is the first part of the sequential screen performed

A

the first half of the sequential screen is done between 11 to 13 weeks 6 days gestation

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11
Q

The nuchal translucency test screens for what disorders?

A

Aneuploidy

congenital anomalies

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12
Q

What abnormalities does quad screen screen for

A

aneuploidy and NTD

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13
Q

integrated and sequential screening screen for what disorders

A

aneuploidy, NTD and congenital anomalies

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14
Q

Cell free fetal DNA screens for?

A

aneuploidy

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15
Q

which first trimester test screen for only aneuploidy?

A

maternal cell PAPP-A hCG and cell free dna

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16
Q

When can chorionic villi testing be done

A

between 10-14 weeks gestation

17
Q

What does CVS testing look for

A

aneuploidy and genetic mutation

18
Q

when is amniotcentesis testing done

A

15-22 weeks

19
Q

what does amniocentesis test for

A

aneuploidy, NTD, genetic mutation

20
Q

What is aneuploidy

A

the condition of having an abnormal number of chromosomes.