Final Flashcards
Zygote
fertilization to 2 weeks
Embryo
2-8weeks
fetus
9 weeks to birth
What is Totipotent?
the earliest developing in the nervous system – they can develop into any type of cell in the body
What is Multipotent?
when cells become more specified
How long after conception does the nervous system develop?
3 weeks after conception
What are the 3 layers in the embryo?
Ectoderm (outer)
Mesoderm (middle)
Endoderm (inner)
What is a Neural Plate?
ectodermal tissue on the dorsal surface of the developing embryo
What are two ways in which cells Migrate?
Somal Translocation and Glial-Mediated Migration
What is Somal Translocation?
an extension grows from the cell and the cell body moves into position along it
can be radial or tangential
What is Glial-Mediated Migration?
a temporary network of radial glial cells develops in the neural tube
only radial migration
What does Radial Migration mean?
moving out
What is Tangential Migration?
Moving in
What is Aggregation?
the process in which neurons align themselves with other developing neurons
What is Aggregation aided by? where are they located?
and how do they work?
Cell-adhesion molecules (CAMs)
located on the surface of neurons
allows the cells to adhere to one another
What are Tropic Molecules?
produced by the target cells being sought by axons
What is Chemoaffinity Hypothesis?
each postsynaptic surface releases a specific chemical label that is uses to attract growing axons to it
What are pioneer Growth cones?
the first cones to travel along a particular route in the developing nervous system
what is Fasciculation?
the tendency for axons to grow along paths established by pioneer growth cones
What is Synaptogenis?
the formation of new synapses, required glial cells (astrocytes)
What is Passive Neuron Death ?
when a neuron dies because it failed to get nutrition
What is Apoptosis ?
active neuron death, the neuron commits suicide, genetically programmed
What is Necrosis?
Passive neuron death, die from malnutrition, a bit dangerous
What is Working Memory?
maintaining relevant information to keep it accessible for short periods of time
What is a critical Period?
when it is absolutely essential for an experience to occur during a particular interval
what is a sensitive period?
when the experience has great effect on development at a certain interval, but can still have effects outside of the interval
What is Tinnitus?
ringing in the ears
produces major organization of primary auditory system
What is neurogenesis?
the growth of new neurons
Describe Autism
a complex developmental disorder that appears before the age of 3
reduced ability to interpret the emotions of others
reduced capacity for social interaction and comminication
What are Autistic Savants
individuals with autism who display incredible abilities in certain areas
What is Williams Syndrome?
is a neurodevelopment disorder
- near-normal language abilities
- normal or superior musical abilities
- very emotionally expressive and socially interactive (hyper sociability)
- mental retardation
- severe visuospatial problems
What is a Stroke?
a sudden interruption in blood supply to the brain that result in brain damage
What are two things that are caused by Strokes?
Infarct
Penumbra
What is Infarct?
dead brain tissue resulting from stroke
What is Penumbra?
“at risk” tissue surrounding the infarct
What are 2 major types of Cerebrovascular Disorders?
Cerebral Ischemia
Cerebral Hemorrhage
What is Cerebral Hemorrhage?
when a blood vessel ruptures and blood seeps into surrounding tissue causing damage
What is Cerebral Ischemia?
a disruption of blood supply caused by a blockage in a blood vessel
What is Thrombosis?
a plug that is formed in a vessel (blood clot, fat, tumour cells etc)
What is Embolism?
a plug that forms in a larger vessel that travels to a smaller vessel
What is Arteriosclerosis?
narrowing of blood vessels because of fat deposits
Describe Ischemia Induced Brain damage?
takes time
does not occur equally in all parts of the brain
mechanisms of damage vary with the brain structure affected
What is a concussion?
when the brain slams against the inside of the skull causing damage to the brains circulatory system