Fighting Disease 19th/20th Century

Question 1

1800’s Main Beliefs of Disease

Answer 1

Supernatural- unpopular MiasmaMicroscopes- Developed

Question 2

Inoculation/Vaccination

Answer 2

18th Cen- Small Pox- Common/Lethal Inoculation- Prevented England- Lady Mary Wortly Montague- Turkey Pus- Scab= Immunity (No Expla)

Question 3

Edward Jenner- Vaccination

Answer 3

EJ- Vaccination= Safer Doc- GloucestershireDairy Maids caught CP= Immune to SPRoyal Society= Experiment= Connection James Phillip injected with SP+CP= Survived

Question 4

EJ Impact

Answer 4

Methods- Successful–> Affected peoples Lives 1798- Published 1802- 30K1803-USA1807- Money 1857- CompulsorySignificant- Injecting one disease prevent another

Question 5

EJ Debate

Answer 5

Doctors Inoculated- Lost Business Not Respected- No Evidence -Royal Soc- Not Publish Religious- Animal disease Not Gov Role

Question 6

Pasteur

Answer 6

57- Pasteur (France)- Wine Processors- Alcohol= Sour Microscope-Germs- Sour (Milk & Beer)Pasteurization- Killed Germs (Heat)Germs caused problems- Link 61- Published 64-Proved

Question 7

Koch

Answer 7

Studied/Read Pasteur work 72- Dye- Identify Germ Identified Germs for 72- Anthrax 82- Tuberculosis 83- Cholera

Question 8

Developments in Drug/Vaccine

Answer 8

Past- Accidental Experiment- Chicken Cholera Kochs Method- Injected Chickens- Died Germs- Exposed to air Chickens Survived81- Anthrax Vaccine 82- Human Rabies

Question 9

Koch & Erlich- Magic Bullets

Answer 9

Magic Bullet- Killed Germs 1909- Paul Ehlrich- Chemical Compound- killed Germs1911- Magic Bullets Gerhard Domagk- Blood Poisoning

Question 10

Penicillin

Answer 10

Stage 1 1928- Treatment of Infection Holiday- Penicillin grew- Mold Killed Germs Antideptic+ Wrote Findings Stage 2Howard Florey + Ernst Chain Mold- Antibiotic Worked on AMIMALS + HUMAN TrailStage 3 Mass Produced 1942- Fleming + Meningitis