Fick Principle Flashcards
To show mastery of the principles of mass balance as covered in the Fick Principle iBook.
The Fick Principle is a statement of conservation of ___________________.
mass or material
The Fick Principle states that the amount of material in a given volume will increase when the material outflow rate is ___________than the inflow rate.
less
If the amount of O2 in a volume of tissue stays constant as the tissue consumes O2 with a constant O2 outflow rate, the O2 inflow rate must be equal to ____________.
the metabolic rate plus the outflow rate
For a tissue metabolizing O2 with constant inflow and outflow rates, the amount of O2 in the tissue will _____________ if the metabolic rate increases.
decrease
For a tissue producing CO2 with constant inflow and outflow rates, the amount of CO2 in the tissue will ____________ if the metabolic rate increases.
increase
The steady state O2 consumption rate of the whole body (vdotO2) is equal to the product of cardiac output (CO) times the ___________________.
∆avO2, the arteriovenous O2 difference
If vdotO2 decreases and CO stays the same, then ∆avO2 must _______________________.
decrease
For a given tissue, if its vdotO2 decreases and its blood flow and CaO2 stay the same, then CvO2 must ________________________.
increase
For the whole body, if vdotO2 increases and CaO2 and mixed venous CO2 do not change, CO must have ___________________.
increased
To measure CO using the Fick method, the O2 content of blood samples from_________________ and ___________________ are needed to estimate the ∆avO2.
any artery, right atrium
To measure CO using the Fick method, respiratory measures of airflow and of inspiratory and expired gas fractions are needed to estimate _____________.
vdotO2
Using the Fick method, you would estimate CO as the ratio of _____________________________.
vdotO2/∆avO2
In applying the Fick Principle to measure mvdotO2 (myocardial O2 consumption rate), one must measure blood flow through the ______________.
coronary sinus, the single venous outlet from the coronary circulation. (This is equal to the sum of flows though all the coronary arteries.)
Myocardial mvdotO2 measurement also requires getting blood samples from _______________ and the _______________.
any artery, coronary sinus
In the ICU, the Fick Principle can be applied to estimate changes in patient hydration by measuring the rates _________________ and _________________.
H20 intake, urinary H2O output
