Fibroid Flashcards

1
Q

Leiomyoma is more common in

A

Nulliparous and obese women

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2
Q

Fibroids can arise uncommonly

A

Broad ligament

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3
Q

8 symptoms

A

AUB
Reproductive failure
Sub fertility
Recurrent pregnancy loss
Pressure and pain
Bladder and bowel dysfunction
Abdominal distension

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4
Q

It response to

A

Hyperoestrogenic state

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5
Q

What type of tumor is it

A

Benign oestrogen dependent tumor

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6
Q

3 forms of degeneration of fibroid

A

Red
Hyaline
Cystic

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7
Q

Risk factors

A

Black race
Low parity
Obesity
Hyperoestrogenic state
COCP use

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8
Q

Classification of fibroid

A

Intramural
Subserous
Submucosa
Cervical
Pedunculated

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9
Q

Protective factor

A

Multiparity
Smoking
GnRH analogue

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10
Q

Red degeneration occurs in

A

Mid second trimester of pregnancy

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11
Q

Red degeneration is characterized by

A

Acute pain

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12
Q

Pressure Symptoms seen in bladder

A

Urinary retention, frequency, urgency and dysuria

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13
Q

Pressure Symptoms seen in ureter

A

Hydroureter
Hydronephrosis
Polycythemia

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14
Q

Pressure Symptoms seen in IVC

A

Hemorrhoids
Edema
Varicose veins

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15
Q

Pressure Symptoms seen in rectum

A

Constipation

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16
Q

Mainstay of diagnosis

A
17
Q

Investigations

A

Ultrasonography (in presence of large fibroid) to exclude hydronephrosis

MRI for the morphology, size and location

FBC
EUCr
Urinalysis
Chest x-ray and electrocardiography

18
Q

Medical treatment of HMB

A

LNG-IUS
Tranexamic acid
Mefenamic acid
COCP

19
Q

Medical treatment

A

GnRH agonist
Danazol
Mifepristone
GnRH antagonist
Progestogen
Tamoxifen
Antifibrolytic agent eg tranexamic acid

20
Q

Surgical treatment

A

Myomectomy
Endometrial ablation
Myolysis
Hysterectomy

21
Q

Examples of GnRH agonists

A

Leuprolide
Buserelin
Goserelin
Naferelin

It induced psudeomenopause

22
Q

GnRH antagonist

A

Cetrorelix
Ganirelix
Degarelix

23
Q

Complications of Uterine artery embolization

A

Fever
Infection
Fibroid expulsion
Ovarian failure

24
Q

Effect of fibroid on Pregnancy

A

Malpresentation
Large for date uterus
Placenta previa and abruptio
Difficulty in palpating fetal part
Poor uterine contractility
Obstructed labour for cervical fi
PPH

25
Q

Effect of pregnancy on fibroid

A

Changes in size of fibroid
More soft
Degenerative changes
Torsion of pedunculated fib
Infection in puerperium