Fibroadenoma

Question 1

Define fibroadenoma

Answer 1

benign breast tumours caused by abnormality of normal development, characterised by focal hyperplasia of stromal and epithelial tissue (collagenous mesenchyme) in one breast lobule
• Giant fibroadenoma = >5cm diameter or >500g

Question 2

Aetiology of fibroadenoma

Answer 2

• Occurs as an aberration of normal lobular development

* Partially hormone related

Question 3

RF of fibroadenoma

Answer 3

• Pre-menopasual
• Low intake of fruit and veg
• Low number of live births

Question 4

Epidemiology of fibroadenoma

Answer 4

• Most patients usually present <30 years of age
• Frequently regress after menopause
• Most common breast tumour in adolescent women
• Incidence declines with increasing age

Question 5

Presenting symptoms of fibroadenoma?

Answer 5

Breast lump

Question 6

Fibroadenoma signs?

Answer 6

Regarding the lump:
o Discreet, with smooth surface
o Painless, without skin or deep fixation
o Extremely mobile – “breast mice”

Question 7

Investigations for fibroadenoma?

Answer 7

•	Ultrasound
o	Oval/round solid lump, lobulated
•	Mammogram
o	Oval/round circumscribed lump, with coarse calcifications
•	Biopsy
o	Epithelial and stromal elements

Question 8

Management for fibroadenoma?

Answer 8

• Observation and reassurance
• Excision
o If painful, large (>4cm) or growing rapidly
• Cryoablation

Question 9

Complications of fibroadenoma

Answer 9

• Giant fibroadenoma

* Slightly increased with cancer with complex fibroadenoma (abnormal cysts, calcifications)

Question 10

Prognosis for patients w/ fibroadenoma?

Answer 10

• 1/3 regress
• 1/3 stay the same
• 1/3 get bigger