Fever in returned traveller Flashcards

1
Q

Presentation

A
  • Fever
  • Diarrhoea/vomitting
  • Jaundice
  • Lymphadenopathy
  • Hepatosplenomegaly
  • Resp symptoms
  • Rash
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

History for traveller with fever

A
  • Travel within last 12 months
  • Dates and duration of stay
  • Time onset
  • Accomodation rural vs urban
  • Recreational activities/exposures - lakes, insects
  • Type of food and water consumed
  • Sexual history
  • PMH and predisposition to infection (eg HIV, DM)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Infections in traveller 0-10 days after exposure causes

A
  • Dengue
  • Rickettsia
  • Viral (inc mono)
  • GI (bacteria/amoeba)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Infections 10-21 days post exposure in traveller causes

A
  • Malaria
  • Typhoid
  • Primary HIV
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

More than 21 days since exposure traveller infection causes

A
  • Malaria
  • Chronic bacterial infections (eg Brucella, coxiella, endocarditis, bone and joint infections)
  • TB
  • Parasitic infections (helminths/protozoa)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Pre-travel immunisations and chemoprophylaxis

A
  • Hepatitis A, B
  • Typhoid
  • Tetanus
  • Childhood vaccines (inc MMR)
  • Yellow fever and rabies where appropriate
  • If travel to malaria areas, malria chemoprophylaxis taken
  • Also enquire about protective meassures eg insect repellent, bed nets
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Clinical examination findings

A

Skin changes
Eye changes
Splenomegaly
Pulse rate slow for fever = typhoid
Neurological changes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Investigations

A
  • FBC
  • LFTs
  • U&Es
  • Malaria blood films +/- antigen detection dipstick at least 3x over 24hrs
  • Blood cultures x2
  • Urinalysis +/- culture
  • Stool culture +/- stool for ova, cysts and parasites
  • CXR
  • HIV, HepB&E, syphillis serology
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Cause of malaria

A
  • Blood protozoa plasmodium species that is transmitted by night biting Anopheles mosquitos
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

species of malaria

A
  • Plasmodium Falciparum = most serious illness
  • 90% originate in Africa
  • Other species P.Vivax and P.ovale mostly SE asia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Presentation of malaria

A
  • Rigors
  • High fevers
  • Malaise
  • Severe headache
  • Myalgia
  • Vague abdo pain
  • N+V
  • Diarrhoea
  • Jaundice and hepatosplenomegaly
  • Bloods - anaemia, thrombocytopaenia, leukopenia, abnormal LFTs
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What can untreated plasmodium falciparum result in?

A
  • Hypoglycaemia
  • Renal failure
  • Pulmonary oedema
  • Neurologic deterioration
  • = death
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Where is typhoid fever common?

A
  • SE asia
  • Southern and central america
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Presentation of Typhoid

A
  • Fever
  • Anorexia
  • Malaise
  • Vague abdo pain
  • Constipation/diarrhoea
  • Dry cough
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Examination of typhoid

A
  • Pulse temp disassociation
  • Hepatosplenomegaly
  • Rose spots
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Bloods for typhoid

A
  • Leucopenia
  • Lymphppenia
  • Raised CRP
  • = non specific
17
Q

Preventing typhoid

A

Vaccines - 70% effective

18
Q

Diagnosis of typhoid

A
  • Isolation of organism in blood cultures, stool, urine, bone marrow and duodenal aspirates
19
Q

Treatment of typhoid

A
  • IV Ceftriaxone
  • Once sensitivies known switch to PO Ciprofloxacin or PO Azithromycin
20
Q
A