Fever Flashcards
1
Q
What is PUO?
A
Fever persisting >2 weeks with no clear diagnosis despite intelligent and intensive investigation.
2
Q
What are the broad categories of PUO causes?
A
Infective, malignant, vasculitides, miscellaneous.
3
Q
What are the infective causes of PUO?
A
- Pyogenic abscess
- TB
- Infective endocarditis
- Toxoplasmosis
- EBV infection
- CMV infection
- Primary HIV infection
- Brucellosis
- Lyme disease
4
Q
What are the malignant causes of PUO?
A
Lymphoma, leukaemia, renal cell carcinoma, hepatocellular carcinoma.
5
Q
What are the vasculitides causing PUO?
A
- Adult Still’s disease
- RA
- SLE
- Wegener’s granulomatosis
- Giant cell arteritis
- Polymyalgia rheumatica
6
Q
What are the miscellaenous causes of PUO?
A
- IBD
- TTC
- Drug fevers
- Sarcoidosis
- Granulomatous hepatitis
- Factitious fever
- Familial Mediterranean fever
