fetal size problems Flashcards
intrauterine fetal demise - definition
fetal death at 20 or more wks
intrauterine fetal demise - diagnosis
abscense of fetal cardiac activity on U/S
intrauterine fetal demise - management
20-23 weeks: dilation + evacuation or vaginal delivery
24 or more: vaginal delivery (regardless fetal presentation: cephalic , breech etc)
the delivery can be delayed for the parents to accept it, but retention of the fetus several weeks can cause coagulopathy
intrauterine fetal demise - complications
coagulopathy after several weeks of fetal retention
evaluation of fetal demise
fetal - autopsy, gross + microscopic examination of placental, membranes and cord, Karyotype + genetic studies
maternal: Kleihauer-Betke test for fetomaternal hemorrhage, antiphsphoipid anomalies, coagulation studies
Fetal growth restriction - definition
weight less than 10th percentile for gestational age
fetal growth restriction - RF
- maternal hypertension
- pregestational DM
- genetic abnormalities
- congenital infection
fetal growth restriction - appearance
large anterior fontanel
2, thin umbilical cord
3. loose peeling skin
4. minimal subcutaneous fat
fetal growth restriction - evaluation
- placenta histopathilogy
2. consider karyotype, urine toxicology, serology
fetal growth restriction - neonatal complications
- polycythemia
- hypoglycemia
- hypocalcemia
- poor thrmoregulation
symmetric vs asymmetric fetal growth restriction regarding onset
symmetric: 1st trimester
asymmetric: 2nd/3rd trimester
symmetric vs asymmetric fetal growth restriction regarding etiology
sym: ch abnormalities, congenital infection
asym: uteroplacental insuf, maternal malnutrition
fetal growth restriction - management
- weekly biophysical profiles
- serial umbilical artery Doppler sonography
- serial growth U/S
type 2 osteogenesi imperfecta - pathophys
AD, type 1 collagen
type 2 osteogenesi imperfecta - U/S
multiple fractures, short femur, hypoplastic thoracic cavity, fetal growth restriction, intrauterine demise