Fetal Programming

Question 1

What is epigenetics?

Answer 1

Heritable changes in gene function that occur without a change in the DNA sequence

Question 2

What are the two mechanisms of action for epigenetics?

Answer 2

1. Alteration of background chromatin proteins which act as scaffolding for DNA during transcription
2. The degree of methylation of the nucleotide bases of the DNA

Question 3

(Hypo/hyper)methylation will cause suppressed genes to be expressed

Answer 3

Hypomethylation

Question 4

DNA methylation prevents ___

Answer 4

transcription

Question 5

What is the primary cause of IUGR in livestock species?

Answer 5

Maternal undernutrition

Question 6

(T/F) The size of the uterine environment can have more of an impact than the genetics

Answer 6

True