Fertility Flashcards
Polyspermia
High number of sperm in the semen sample >250M per ml
Normospermia
normal characteristics of sperm in the semen sample
Oligospermia
Reduced number of sperm in the sample
- Mild = 10-15M/mL
- Moderate = 5-10M/mL
- Severe = <5M/mL
Cryptozoospermia
Very few sperm in semen sample <1M/mL
Azoospermia
Absence of sperm in semen
Lifestyle causes of Reduced sperm?
Hot baths
Tight underwear
Smoking, Alcohol, Caffeine
Raised BMI
GnRH agonist used to prevent menstrual cycle in IVF
Goserelin
GnRH antagonist used to prevent menstrual cycle in IVF
Cetrorelix (SC injection)
What causes ovarian hyperstimulation syndrome?
Human chorionic gonadotrophin (hCG) used in ovarian stimulation process
3 main symptoms of OHSS?
Oedema
Ascites
Hypovolaemia
OHSS tends to present within how many days of hCG injection?
7 days
Name 5 symptoms of OHSS
- Abdominal pain and bloating
- Nausea and vomiting
- Diarrhoea
- Hypotension
- Hypovolaemia
- Ascites
- Pleural effusions
- Renal failure
- Peritonitis
5 main supportive treatment options for OHSS?
- Oral fluids
- Monitoring urine output
- LMWH to prevent VTE
- Paracentesis (PRN)
- IV colloids e.g. human albumin solution
5 management options for male factor infertility?
Surgical sperm retrieval Surgical correction of obstruction Intra-uterine insemination Intracytoplasmic sperm injection Donor insemination