Fertility

Question 1

Lydia cells do what?

Answer 1

Produce testosterone

Question 2

Functions of testosterone?

Answer 2

Increase in bone and muscle mass
Stimulates Sertoli cells
Stimulates spermatogenesis

Question 3

Functions of FSH, LH and inhibin in a man?

Answer 3

FSH stimulates spermatogenesis
LH stimulates testosterone production
Inhibin is released from the Sertoli cells as a -ve feedback mechanism on the FSH

Question 4

What can oxidative stress cause?

Answer 4

Self-fertility

Question 5

What is infertility?

Answer 5

A woman of reproductive age who has not conceived after 1 year of unprotected sex

Question 6

Difference between primary and secondary infertility?

Answer 6

In secondary there was previously a pregnancy

Question 7

40% of 2ndary infertility is…

Answer 7

Tubal disease

Question 8

Male history:

Answer 8

Maldescent
Trauma
STI
Mumps
Orchitis
Surgery and drugs

Question 9

What can damage Fallopian tube patency?

Answer 9

Ectopic pregnancy
Pregnancy
Infection (STI)
Endometriosis
Surgery
Pelvic inflammatory disease

Question 10

Low number of eggs indicated by…

Answer 10

Low AMH

Question 11

Obstructive azoospermia:

Answer 11

Blockage with normal sperm and FSH

Question 12

Non-obstructive azoospermia:

Answer 12

Small testes
Raised FSH
Testicular failure - 50% have evidence of spermatogenesis on biopsy

Question 13

Which hormones should you test in a day 2-4 hormone profile?

Answer 13

FSH
LH
Prolactin
TSH