Ferrets Flashcards
What family do ferrets come from?
Mustelidae
Are ferrets closely related to mongoose?
NO
What sort of diet do ferrets need?
Strict carnivores
What should you remember about their mouths (2 things)?
Dental disease similar to cats, broken canines
What is a common GI disease ferrets get?
Gastric and duodenal ulcers
What bacteria is a problem for ferret GIs?
Helicobacter
What are ferrets a good model to test?
Anti-emetics
What is unique about their GIT?
Have jejuno-ileum b/c can’t differentiate the two
Do ferrets have a cecum?
No
What can affect intestinal motility in the ferret?
Cervical (mechanical from scruffing) vagal stimulation
What are 2 common causes of acute gastric ulcers?
FB
Toxins
What is a common causes of chronic gastric ulcers?
Infectious disease
What organism is a very common cause of gastritis?
Helicobacter mustelae
What are 5 clinical signs of Helicobacter gastritis?
Bruxism Ptyalism Anorexia Chronic weight loss Melena
Do you expect vomiting with Helicobacter gastritis?
No, but can see blood-tinged vomit sometimes
How is Helicobacter gastritis diagnosed (2 ways)?
Fecal occult blood (remember carnivorous diet though)
CBC (regenerative anemia)
What makes it difficult to diagnose Helicobacter (2 things)
Difficult to culter
Endemic
What 4 things do you give to treat Helicobacter gastritis?
Abx (Metronidazole)
PPI (Sucralfate)
Mucosal protectant (Pepto)
H2 Receptor agonist (Famotidine or Ranitidine)
If you give Pepto to ferrets as a mucosal protectant, what do you need to be aware of?
NSAIDs in Pepto
What are clinical signs for FB?
Similar to that in other animals
What aer 3 ways you can dx a FB in a ferret?
Palpation
Radiographs
Exploratory
What 4 methods can be used to treat a FB?
Lubricants
Antibiotics
Fluids
Sx when needed
How does a hairball look on RADs with contrast?
See a stringy effect
What do you need to get in cases of ferret diarrhea?
A detailed history (where ferret came from, description of diarrhea, home environment, behaviour)
What are 6 causes of diarrhea?
FB Viral Dietary indiscretion IBD Proliferative bowel dz Lymphoma
What major virus causes diarrhea?
Corona virus causes ECE (epizootic catarrhal enteritis)
NOTE: Similar to FIP
What 2 bacteria cause proliferative bowel dz?
Campylobacter
Lawsonia
What is IBD usually?
Lymphoblastic
What are 4 possible causes of IBD?
Genetics
Food allergy
Prednisone (can allow Helicobacter overgrowth)
Azothiaprine and metronidazole (both immunosuppressive) and Vit B12
What type of diarrhea do you see with ECE?
Profuse, mucoid, green slime
What causes Epizootic catarrhal enteritis?
Coronavirus
What ferrets are susceptible to ECE?
Older ferrets
What 3 clinical signs will you see with ECE?
Lethargy
Dehydration
Anorexia
What does ferret systemic coronavirus resemble?
Looks like FIP b/c causes pyogranulomatous inflammation in peritoneum, liver, kidneys, pancreas etc.
If you have mucoid stool, what should you think of?
Parasites
If you have melena, what 3 things should you think of?
FB
Hairball
Ulcer
If you have other abnormal stool forms, what should you think of?
Metabolic dz
IDB
Where is the ferret lung field?
From 1st-10th intercostal space
How many ribs do ferrets have?
14
How many sternebrae do ferrets have?
9
How are lungs divided in the ferret?
Same as dogs and cats
Left - cranial and caudal lobes
Right - cranial, middle, caudal and accessory
What must you remember with ferret influenza?
Can get it from humans, so make sure owners know that sick people should stay away from ferret or at least wear a mask
How long does ferret influenza last?
7-14 days
What 4 things can you give to treat ferret influenza?
Support
Antihistamines
Cough suppressants
Prophylactic abx (prevent progression to pneumonia)
What are 3 causes of pneumonia in ferrets?
Aspiration (meds or vomit)
Bordatella
Pasturella
How do you treat ferret pneumonia (2 drugs)?
TMS
Chloramphenical
How can you prevent pneumonia?
Separate from sick dogs/separate boarding facilities
What dz is fatal in ferrets?
Canine distemper
NOTE: NOT TX, MUST VACCINATE
How fast does distemper progress?
12-42 days
What are 3 ways distemper is transmitted?
Direct contact
Fomites
Aerosolization
What are 5 major clinical signs of distemper?
Anorexia Pyrexia Chin dermatitis Nasoocular discharge Hardpad (hyperkeratosis)
What can you see in the CNS with Distemper?
Non-suppurative encephalitis/demyelination
How do you dx a ferret with heartworm (2 ways)?
Echo
Snap test
What clinical signs will you see with HW?
Similar to dog
What two things can you use to treat HW in a ferret?
Thiacetarcemide
Ivermectin plus steroids
How do you prevent HW in ferrets (2 ways)?
Heartgard
Feline Revolution off label
Can ferrets have allergies?
Yes
In a ferret with respiratory distress, what must you always remember to check?
Teeth, could have tooth root abscess
What 3 things should you consider if there is blood or continuous sneezing?
FB
Rhinitis
Sinusitis
What can cause urolithiasis and urinary tract obstruction?
Poor quality diet -> causes crystals to form
What are 2 other diseases that can cause urinary tract obstruction?
Adrenal dz
Prostatomegaly
How can you treat urinary tract obstruction or urolithiasis (3 ways)?
Urinary catheter
Fluids
Sx
What are 2 things you can do to help in urinary tract obstruction or urolithiasis aftercare?
Diet change
Antimicrobial therapy
How do you pass a urinary catheter in a female ferret?
Ventral recumbency, back end elevated.
Urethral opening on floor of urethral vestibule ~1cm cranial to clitoral fossa
How do you place a urinary catheter in a male ferret?
Dorsal recumbency, penis exteriorized
Urethral opening on ventral surface of penis
Dilate opening with 24G IVC, then insert urinary cath
How do you treat hyperestrogenism in a ferret?
HCG injection to stop estrus, and OVH when stable
If a ferret is not bred, what 2 issues can she develop?
Estrogen toxicity
Bone marrow suppression
What is prostatic dz often secondary to?
Adrenal dz
What can prostatic dz lead to?
Urethral obstruction
What are 4 ways to treat prostatic dz?
Tx adrenal dz
Abx
Drain infected fluid
Surgical debulking
What is the most common cutaneous neoplasia?
Mast cell tumors and Basal cell tumors
What are 3 major points to know about mast cell and basal cell tumors?
They don’t typically metastasize
Can be surgically removed
Prognosis is good
What 2 types of cutaneous neoplasias metastasize?
Fibrosarcoma
Sebaceous gland adenoma
What are 2 common dermatophytes we see with ferrets?
Microsporum canis
Trichophyton metagrophytes
How are the dermatophytes transmitted?
direct contact
How do you treat the dermatophytes (4 ways)?
Iodine shampoo
Chlorhexidine shampoo
Griseofulvin
Disinfect environment
Do ferrets get fleas?
Yes
Do ferrets get ear mites?
Yes
What 3 places do you see generalized sarcoptes?
Face
Pinna
Ventrum
What 3 places do you see localized sarcoptes?
Paws
Nails
Toes
How do you diagnose sarcoptes?
Skin scrape
How do you treat sarcoptes?
Ivermectin or lyme sulfur dips
What is the most common cause of otitis media/interna?
Pasturella multiocida
How do you diagnose otitis media/interna?
RADs
What are 3 treatments for otitis media/interna?
Enrofloxacin systemic and topical
Chloramphenicol
Flush ears with saline (under anaesthesia)
What should be your top 2 differentials if you suspect a viral dz causing neurologic signs?
Distemper (more likely)
Rabies
What is the prognosis of distemper
Grave
If neurotropic phase of distemper develops, what is the best course of action?
To elect euthanasia because it can be very painful and stressful
What should be done if you suspect rabies?
Euthanize and send to state lab for testing.
NOTE: Keep Rabies on ddx for rabbits and GPs and other rodents with neuro signs and exposure to wildlife
What are the 2 big endocrine diseases of small ferrets?
Adrenal dz
Insulinoma
What is the most common endocrine dz of ferrets?
Adrenal dz
What is the typical presentation of a ferret with adrenal dz?
Perfectly symmetrical bilateral alopecia
What adrenal gland dz will you NOT see in a ferret?
Hypersecretino of cortisol (Cushings)
What is good to remember about adenomas, adenocarcinomas and adrenocarcinomas?
Lots are benign, but should never assume. If you remove it, biopsy
What is adrenal glang dz going to be a hypersecretion of?
Sex hormones
What is adrenal dz related to in ferrets?
Early spay/neuter as altered animals will again develop sex hormones
What 4 tests can’t you use in ferrets for endocrine testing?
Serum cortisol (not elevated)
ACTH stim test/Dex suppression test
Urinary Cortisol:Creatinine (not a specific indicator)
What is the only reliable means of diagnosing adrenal dz?
Serum concentrations of steroid hormones at Tennessee
What are 8 clinical signs of adrenal dz?
Symmetrical alopecia Pruritis Erythema Secual behaviours Vulvar enlargement Bone marrow toxicity Urinary obstruction Stronger smell
How do you treat adrenal dz medically?
Leuprolide acetate monthly injection
NOTE: This is a GnRH agonist
Why is adrenalectomy not common to see done (2 reason)?
Right adrenal glad is REALLY close to vena cava
Recurrence likely in other gland if only unilateral
What is an insulinoma?
Beta cell tumor of the pancreas causing hypersecretion of insulin
What are 8 clinical signs of a insulinoma?
Decreased activity Weight loss Difficult arousal from sleep Hypothermia Ptyalism Mental dullness Tremors Collapse
How do you dx an insulinoma?
BG
What can be really frustrating about insulinomas?
Lots of little ones pop up that are not mets, makes this really difficult to remove surgically
How do you treat an insulinoma?
Prednisone to block peripheral uptake of glucose and increase hepatic gluconeogenesis
T/F: After a nodulectomy or partial pancreatectomy, pancreatitis is rare.
True
What age do ferrets seem to get lymphoma?
6mos -1yr or 3-5 yrs
What is the description of lymphoma in a young ferret?
Acute onset, rapidly progressive, multicentric, involves lung and kidney (among others)
What is the description of lymphoma in an older ferret?
Chronic, better survival times
What are the 3 general clinical signs of lymphoma?
Anorexia
Weight loss
Lethargy
What are 4 clinical signs of GI/abdominal lymphoma?
Emesis
Diarrhea
Tenesus
Splenomegaly
What are 3 clinical signs of mediastinal lymphoma?
Dyspnea
Coughing
Regurgitation
How do you diagnose lymphoma?
Biopsy
What are 3 ways you can treat lymphoma?
Surgery
Chemo
Steroids
What is a ferret chordoma?
Smooth, round, firm mass that develops on the tail tip from the original notocord
Can a chrodoma metastasize?
Yes
How do you treat a chordoma?
Tail amputation
What is Aleutian dz?
A parvovirus that lays dormant until animal is stressed
Is an immune mediated disorder
How is Aleutian dz transmitted?
ferret-ferret or mink-ferret with aerosolization OR contact
VERY hardy in environment
How is Aleutian dz characterized?
Hypergammaglobulinemia
What are 5 clinical signs of Aleutian dz?
Chronic wt. loss Cachexia Malaise Melena Posterior paresis
What is the progression of Aleutian dz?
Vasculitis -> Multiple organ failure -> Sudden death
What is the treatment for Aleutian dz?
None…
What 3 signs do you see in cardiac dz?
Cyanosis
Tachypnea
Increased CRT
What might you notice about the jugular in cardiac dz?
Distended or pulses
What might you hear in the lungs with a case of cardiac dz?
Pulmonary crackles
Ascites
What are 4 major radiographic signs you’ll see in cardiac dz?
Globoid heart
Diffuse interstitial pattern
Hepato/splenomegaly
Pleural effusion
Describe a normal ECG.
Small P wave
Large R wave
Short QT interval
Elevated ST segment
What is the normal range for a ferret heart rate?
180-230bpm
What is the most common cardiac dz in ferrets?
DCM
What are 3 things that we should recommend in cases of cardiac dz?
O2
Low sodium diet
Diuretics
What is the prognosis of cardaic dz?
Poor, even with aggressive therapy
How common is splenomegaly and how is it typically found?
Very common, incidental finding
What are 3 causes for primary splenomegaly?
Lymphoma
Splenic neoplasia
ADV
What are 4 causes for secondary splenomegaly?
Insulinoma
Adrenal dz
Cardiac dz
Dental dz
What are some indications for a splenectomy?
Discomfort Inflammation Neoplasia Torsion Rupture Abscess
What is hypersplenism?
Excessive destruction of RBCs, WBCs and/or platelets (cytopenia on CBC, confirm with bone marrow aspirate)
How do you dx hypersplenism?
Cytopenia on CBC
How do you confirm hypersplenism?
Bone marrow aspirate
What are 3 indications for a splenic aspiration?
Anything irregular with the spleen
Anemia of unknown origin
Lymphoma/sarcoma
What is the technique for splenic aspiration?
Percutaneous with rigid restraint of spleen using a 25G needle with 6cc syringe