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Dermatologia > Fermacodermias > Flashcards

Fermacodermias Flashcards

1
Q

fármacos mais comumente implicados

A

penicilina, sulfonamidas, anticonvulsivante aromático, aines, ieca, hidralazina, alupirinol

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2
Q

características exantema

A

2 semanas após início

erupção eritematosa maculopapular

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3
Q

urticária

A

placas eritematosas, bora irregular, centro pálido, pruriginosa

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4
Q

angioedema

A

edema mole

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5
Q

tratamento urticária/angioedema

A

suspensão da droga

anti histamínico (antagonista h1)

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6
Q

eritema pigmentar fixo

A

eritematosa -> acastanhadas, bordos bem definidos, não pruriginosa
LESÃO RECORRENTE

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7
Q

vasculite

A

deposição de imunocomplexos

Rash purpurico

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8
Q

eritema multiforme

A

lesões em alvo (típicas: 3 ou mais anéis )

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9
Q

droga SEJ e NET

A

sulfonamida

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10
Q

SSJ e NET

A

duas ou mais áreas de mucosa, exantema eritematoso, alvo atípico, desnudamento cutâneo

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11
Q

diferença SSJ e NET

A

SSJ < 10% pele desnuda

NET > 30 %

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12
Q

fisiopatologia SSJ

A

ataque TCD8 aos queratinocitos, muito TNF-alfa

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13
Q

sinal de Nikolsky

A

descolamento epiderme após tração

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14
Q

tratamento SSJ e NET

A 
reposição hidroeletrolitica 
nutrição enteral
medida oftalmológica
debridamento
controle da dor
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15
Q

DRESS

A

febre, rash (exantema mobiliforme, eritrodermia esfoliativa), linfadenomegalia, hepatomegalia, eosinofilia

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Dermatologia (6 decks)

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