Female Urology and Reproductive Flashcards
Menstrual Cycle - Mencarche - Normal
11 to 15 years
Menstrual Cycle - Length of cycle - Normal
20-45 days (avg 28 days)
Menstrual Cycle - Ovulation - Normal
14 days
Menstrual Cycle - Menstruation - Normal
5 days
Menstrual Cycle - Menstrual pain
Cramping before bleeding begins
Peaks 24 hrs
Decreases gradually
Does not limit function
Menstrual Cycle - Length of cycle? - Abnormal
Infrequent menstruation - more than 31-35 days apart
OR
Frequent menstruation - less than 2 weeks apart
Menstrual Cycle - Bleeding - Abnormal
Lasts more than 7 days
Menstrual Cycle - Menstrual pain - Abnormal
Severe abdominal cramping that limits function
Occurs days before bleeding
Lasts more than 3 days
Pain inc as bleeding dec
Age related changes - Perimenopause/Menopause transition
Usually occurs between 45-50 years old
Time leading up to complete menopause is usually 3-4 years
Hormonal levels decline and irregular cycle occurs
Age related changes - menopause
End of reproductive potential with permanent cessation of ovarian function
Age related changes - postmenopause
Live 1/3 of life cycle in this stage with increased life expectancy
Estrogen plays protective role - so keep that in mind with post menopausal patients
Menopause - clinical implications
1 Increased urinary incontinence
2 Increased risk of pelvic organ prolapse
3 Increased risk of dyspareunia/pain
Menopause - clinical implications - Inc in urinary incontinence includes what
Inc post void residual
Dec power of detrusor mm
Dec pelvic floor mm and collagen support
Menopause - clinical implications - Inc risk of pelvic organ prolapse includes what
Dec estrogen is associated with collagen changes and dec vascularity of supporting tissue
So CT not holding things up
Menopause - clinical implications - Inc risk of dyspareunia/pain includes what
Dryness of vagina
Dec vascularization of the urethra with dec blood flow and blood volume
Genital atrophy from dec hormones
Menopause - clinical implications - impacts what
ALL SYSTEMS!
Menopause - clinical implications - GI system
Bloating
Abdominal pain
Irritable bowel
Menopause - clinical implications - Integumentary
More thinning
Bruise easier
Menopause - clinical implications - Endocrine
Mostly estrogen is declining
Can lead to decrease in metabolism
Menopause - clinical implications - Cardiovascular
Inc in truncal obesity can inc risk of CV complications
After menopause - women become higher risk
Menopause - clinical implications - Musculoskeletal
OP
Fractures
Postural changes
Menopause - clinical implications - Nervous
More impairments in cognitive function
Sleep disturbances
Pelvic floor mm - description
Skeletal muscle sling from pubic bone to coccyx - surrounds the urethra, vagina, and rectum
Purpose of the pelvic floor mm
Support internal pelvic organs
Closes off urethra for continence
Closes off rectum for continence
Participate in sexual arousal and orgasm
Puborectalis
Most medial
Pubic bone - wraps around urethra, vaginal opening, and rectum
Like a lasso around the openings
Micturation - phases
Storage/Filling phase
Emptying phase
Micturation - Storage/Filling phase
Parasympathetic receptors are inhibited
Sympathetic receptors are stimulated
Sympathetic will keep detrusor relaxed and keep bladder neck contracted
Micturation - Emptying phase
Sympathetic receptors are inhibited - relaxation of bladder neck, cessation of stretch receptors
Parasympathetic receptors are stimulation - detrusor contraction is strengthened
Micturation - Sympathetic =
Storage
Micturation - Parasympathetic =
Emptying phase
Micturation - bladder fills at what rate
Constant rate!
15 drops/minute
Micturation - sensations and capacity
First sensation to void = 40% capacity (about 150 mL)
First desire to void is about 60% capacity
Strong desire to void is at more than 90% capacity (about 400-500 mL)
Micturation - patient education
Nerve signals from bladder go to brain sacral micturation center
Brain tells bladder that it cannot contract
Signals to bladder neck/outlet to contract more so can continue filling
(outlet pressure more than bladder pressure)
Pelvic floor mm dysfunction - classified by
symptoms, signs, and conditions
Pelvic floor mm dysfunction - 5 symptoms/5 types of dysfunction
1 Lower UT symptoms 2 Bowel symptoms 3 Vaginal symptoms 4 Sexual function 5 Pain
Pelvic floor mm dysfunction - 5 symptoms/5 types of dysfunction - Lower UT symptoms
Urinary incontinence
Urgency
Frequency
Pelvic floor mm dysfunction - 5 symptoms/5 types of dysfunction - Bowel symptoms
Obstructed defecation
Functional constipation
Fecal incontinence
Rectal/Anal prolapse
Pelvic floor mm dysfunction - 5 symptoms/5 types of dysfunction - Vaginal symptoms
Pelvic organ prolapse
Pelvic floor mm dysfunction - 5 symptoms/5 types of dysfunction - Sexual function
Orgasmic dysfunction
Dyspareunia in women
Erectile and ejaculatory dysfunction in men
Pelvic floor mm dysfunction - 5 symptoms/5 types of dysfunction - Pain
Chronic pelvic pain
Pelvic pain syndrome
Pelvic floor dysfunction - underactive PFM
1 Dec strength and endurance
2 Poor coordination of PFM with changes in intraabdominal pressure (cough, sneeze, laugh)
3 Urinary or fecal incontinence, prolapse
Pelvic floor dysfunction - underactive PFM - Causes
PFM avulsion (maybe childbirth) Age High BMI Type 2 D Heavy lifting Constipation Overstretching of the PFM and CT Pudendal nerve damage Birth trauma Dec mobility
Pelvic floor dysfunction - overactive PFM
1 Inc in PFM tension, active spasm
2 Incoordination of PFM causing dysfunction of urogenital or colorectal systems
3 Musculoskeletal pain from hypertonicity
PFM Dysfunction Diagnosis - Underactive
1 Urinary incontinence
2 Prolapse
3 Fecal incontinence
PFM Dysfunction Diagnosis - Overactive
1 Levator ani syndrome 2 Chronic pelvic pain 3 Vaginismus 4 Tension myalgia 5 Coccygodynia 6 Interstitial cystitis/painful bladder
Pelvic floor dysfunction - overactive PFM - Causes
Multifactorial Symptom of other pathology Job stress, menstrual cycle, constipation Hx of abuse Habitual postures Orthopedic malalignment
Urinary incontinence - is what
symptom of ANY involuntary leaking of urine
Urinary incontinence - prevalence
35-38% in women
often is underreported though
Stress urinary incontinence is what
Involuntary leakage with activities, sneezing, or coughing
Anything that causes inc abdominal pressure
Stress urinary incontinence is due to
Due to increased abdominal pressure relative to urethral closure pressure
Urge urinary incontinence is what
Sudden, unexpected urge with uncontrolled loss of urine
Mixed urinary incontinence is what
Combination of both stress and urge
Is the most common
Less common types of urinary incontinence - Insensible UI
Loss of urine where the person has no idea how it occurred
Less common types of urinary incontinence - Continuous UI
Complaints of continuous leakage
Less common types of urinary incontinence - Postural UI
Leakage with changes in position - most common is leaning over and then when they come back up
Or also from sit to stand (this is huge with males post prostectomy)
Less common types of urinary incontinence - Nocturnal enuresis
Leakage of urine while sleeping
Less common types of urinary incontinence - Coital UI
Leakage while involved in intercourse
UI epidemiology - any urine leakage during physical or non physical activity, or before reaching toilet
- 1 % women
15. 1 % men
UI risk factors
1 PFM damage 2 Pelvic organ prolapse 3 Sphincter mm weakness or damage 4 Pudendal nerve damage 5 Neurological disorder 6 Psychogenic 7 Constipation 8 Medications 9 Inc age or dec cog function 10 Impaired mobility 11 Pregnancy or Obesity
Neurogenic Bladder Disorders are what
Voiding dysfunction from neurologic conditions caused by an interruption of the nerve supply to the bladder
Can be UMN or LMN lesion
Neurogenic Bladder Disorders - Clinical presentation
Smaller urine volume on voiding
Incontinence
Urgency and frequency
Higher rates of UTIs
Bladder Storage Symptoms
Inc daytime urinary freq Nocturia Nighttime freq Urgency Overactive bladder symptoms
Normal bladder habits - how many times a day/night
4-8 times a day
At night shoulder be 0-1 if under 65, 1-2 if over
Normal bladder habits - time between urination
Generally urinate every 2-5 hours
Normal bladder habits - Length of urination
8-10 sec
Normal bladder habits - Urine color
light yellow
Dietary recommendations - aim for how much fluid/day
48-64 ounces of water
Concentrated urine will irritate bladder
If over 80-100 oz is associated with inc incontinence
Dietary recommendations - Bladder irritants
Coffee, tea, soda, medications, caffeine, chocolate, alcohol, nicotine, carbonation, high acid, artificial sweeteners
Behavior Training - Forms of behavioral treatment for urinary incontinence
Bladder training Use bladder diary/voiding log Urge suppression techniques Dietary modifications Appropriate fluid intake Weight loss Pelvic floor exercises
Bladder training - Bladder diary includes what
How often How many leaks Size of leak Activity during leak Amount and type of fluid consumed Amount and fluid voided Number of pads used per day Amount voided
Bladder training - Bladder diary - how often is most effective
Have them do it for 3 days - gives you enough info and inc compliance/honesty
Bladder training - Bladder diary - defining the size of the leak
Drops to a teaspoon = small
Tablespoon = moderate
1/4 of a cup = significant lea (will go through clothes)
Bladder training - urgency control
1 Sit - perineal pressure inhibits bladder - sitting on the perineum can inhibit it
2 Relax
3 Distract
4 do NOT rush
5 When urge dissipates, wait until rx time or 5-15 min and then walk to toilet
Bladder training - what else besides bladder control techniques
Scheduled voiding
Avoid just in case urinating
Prompted training for cognitive impaired or SNF/LTC
Purpose of bladder training
Improve bladder control by changing bx Break cycle of urgency/frequency Dissociate functional bladder capacity Inc functional bladder capacity Inc self confidence Correct improper voiding habits
Dysfunctional bladder habits
Delaying bladder too long
Hoovering over toilet
Bearing down to initiate or complete urination
Not allowing full time for bladder to empty
Voiding just in case
Failing to wipe front to back
Urinary frequency over 10x/day
Treatment of underactive PFM
Bx training Postural education Coordination of breath and PFM Strengthening PFM, abs, back Inc PFM coordination, endurance, and force by skilled PT with training for internal eval
Treatment of overactive PFM
Bladder retraining
Schedule interval is critical
Urgency control
Avoid just in case voiding
Treatment of overactive PFM - Schedule interval
Short mandatory voiding interval for mod-severe urgency
No sooner than __ hours for mild symptoms
Treatment of overactive PFM - Urgency control
Sit - perineal pressure to inhibit bladder
Relax
Distract with pos thoughts of being in control
Do NOT rush
When urge dissipates, wait until rx time or 5-15 min and walk to toilet
Measurement of PFM dysfunction - ICS definition
Pathophysiology = cause Impairment = non functioning PFM (over or under) Disability = leakage
Pelvic organ prolapse is what
Descent of one or more of the pelvic organs into the vagina due to the loss of fibromuscular support
Pelvic organ prolapse is described by
the compartment of the vagina in which it occurs
Pelvic organ prolapse - Cystocele
Anterior vaginal wall prolapse
Most common
Bladder falling forward
Pelvic organ prolapse - Retocele
Posterior vaginal wall prolapse
Rectum coming forward
Pelvic organ prolapse - Apical
the loss of support of the uterus
vaginal vault
Uterus coming down and vaginal vault coming down
Common after hysterectomy
Pelvic organ prolapse - epidemiology of ages 18-82 years
Stage 1 = 43.3 %
Stage 2 = 47.7%
Pelvic organ prolapse - etiology
Pelvic mm weakness, ligamentous lax Multiple preg and deliveries Obestiy Traumatic Prolonged labor/delivery Excessive and rep. straining with bowel mvmnts Aging and DM inc risk Neuro conditions Posture and IAP management
Prolapse risk factors
1 Multiple preg and deliveries 2 Prolonged labor 3 Improper bearing down with delivery 4 Nerve damage with delivery 5 Obesity 6 Aging 7 Chronic constipation 8 Chronic heavy lifting 9 Chronic cough
Prolapse symptoms
Urinary
Bowel
Sexual
General
Prolapse symptoms - urinary symptoms
Incontinence, freq, urgency, hesitancy
Position change or manual reduction of prolapse needed to initiate/complete voiding
Weak/prolonged stream
Incomplete emptying/actual or sensory
Leaking immediately or dribbling post void
Prolapse symptoms - bowel symptoms
Feelings of incomplete emptying/obstruction
Straining, digital evacuation
Splinting of vagina or perineum so that they aren’t pushing more out with bowel mvmnt
Prolapse symptoms - Sexual symptoms
Due to changes in vagina anatomy
Dec lubrication and arousal
Dyspareunia
Prolapse symptoms - general symptoms
Pressure/heaviness of vagina
Bulge coming out of vagina
General pelvic pain/maybe LBP
Worse at end of day with prolonged standing/walking
Urinary, bowel, sexual symptoms may be associated
Self conscious
Impairments with prolapse
High or low tone in levator ani Posterior pelvic tilt Glut weakness Poor management of abdominal pressure Poor coordination/stabilization of core Improper voiding techniques
Diagnosis pf pelvic organ prolapse
Pelvic exam
Treatment of pelvic organ prolapse
Rehab for underactive pelvic floor Vaginal pessary Corrective surgery Weight loss if obese Hormonal replacement therapy Control of constipation and vasalva activities
Only ___% of patients actually seek tx for POP
10-20%
Considerations for udneractive PFM
Management of intra-abdominal pressures Breath coordination Posture - thoracolumbar ext, neut pelvis Mm coordination with functional activity Bx training - hydration, diet, urgency, freq
Pelvic pain - diagnoses consist of
Endometriosis Dysmenorrhea Hypertonus disorders Interstitial cystitis GI disorders
Pelvic pain - pain and hypertonus disorders may be related to
Delayed healing perineal lacerations Trauma with delivery Pelvic obliquity Multiple gyn/visceral diagnoses Cauda equina Scar tissue/adhesions Mm spasm/guarding Abuse
Tx of overactive (hypertonic) PFM disorders
Posture Joint alignment Aerobic exercise Pain education Manual therapy Stretching Biofeedback/Relaxation training Dilators for stretching
Painful bladder syndrome/Interstitial cystitis is what
Recurring pelvic pain, pressure, or discomfort in the bladder and pelvic region
Often associated with urinary frequency and urgency
Painful bladder syndrome/Interstitial cystitis - what is often a co-morbidity or the driver of the symptoms
Hypertonicity of abdominal and pelvic floor muscles
Painful bladder syndrome/Interstitial cystitis - exacerbated by
emotional or physical stress
Painful bladder syndrome/Interstitial cystitis - Flares can ocur with
Consumption of acidic food
Painful bladder syndrome/Interstitial cystitis - frequent comorbidities include
fibromyalgia, endometriosis, migraines, IBS, vulvodynia
Painful bladder syndrome/Interstitial cystitis - treatment
No cure Manage s/s and treat bladder lining Pharm - pain and bladder s/s PT Surgery
Painful bladder syndrome/Interstitial cystitis - - PT treatment
Overactive PFM and myofascial pain in 85%
Bx retraining and dietary modifications
Pain neuroscience education
Painful bladder syndrome/Interstitial cystitis - Surgery
Neuromodulation at S3 with interstim unit for treatment of urgency, frequency, retention
Enodmetriosis is what
A disorder that occurs when endometrial tissue grows outside of the uterus
Tissue is biochemically and endocrine active
Endometriosis - what does it look like
Chocolate cysts - formed by the implanted tissue as it reacts to the normal cycle
Endometriosis - most common sites
Ovaries Fallopian tubes Broad ligament Pouch of douglas Bladder Pelvic mm Perineum Vulva Vagina Intestines
Endometriosis - Epidemiology
Affects W of all groups
2-20% of american women affected
45% of all abdominal pain
Enometriosis risk factors
Early age menarche Short menstrual cycles Long duration of menstrual flow Inverse relationship to parity Family hx
Endometriosis clinical presentation
Dysmenorrhea
Dyspareunia
Infertility
Pain - low back, pelvis, thigh, abdominals
Endometriosis treatment
Depends on age, reproductive desires, stage of disease and symptoms
None Pharm Surgery PT Alternative tx are increasing
Endometrial (uterine) cancer
Most common gynecological cancer
4th most common cancer for women
Endometrial (uterine) cancer - risk factors
Age (avg is 60, 75% in post menopausal women, 25% premenopausal, 5% in under 40)
Obesity
Nulliparity (no children)
No genetic component
Endometrial (uterine) cancer - Decrease risk with
Exercise!
80% less likely compared to women that do not exercise
Endometrial (uterine) cancer - most common symptom
Abnormal vaginal bleeding (esp post menopausal)
Endometrial (uterine) cancer - diagnosis made by
tissue cytology exam
Endometrial (uterine) cancer - treatment
surgery and radiation
Endometrial (uterine) cancer - prognosis
good in early stages (90%)
poor for late stages (10%)
Cervical cancer- risk factors
HPV (93%) Maternal use of DES Smoking Hormonal contraceptive use High parity (births) Low SES Ethnic background Young age of first intercourse Multiple sex partners (more than 5)
Cervical cancer - diagnosis
Pap screen/test can detect problems early
Cervical cancer - treatment
Prevention, Gardisil vaccine
Depends on stage - hysterectomy, radiation therapy
Cervical cancer - prognosis
Early stages is highly curable (85%)
Advanced (40%)
Ectopic pregnancy is what
Fertilization and implantation of the embryo outside of the uterine cavitiy (more than 95% are in fallopian tube)
Ectopic pregnancy presents with
Amenorrhea or menstrual irregularities with unilateral or bilateral abdominal and back pain
Ectopic pregnancy s/s of…
normal pregnancy with fatigue, nausea, breast tenderness and inc urinary freq
Ovarian cystic disease
Most common during reproductive years
Affects 3-7% of all women
Caused by hormonal imbalances
Ovarian cystic disease - presentation
Low back and pelvic pain Abdominal pain and bloating Painful urination, bowel movements and itnercourse menstrual irregularities large cysts can lead to infertility
Ovarian cystic disease - Diagnosis
US Lab tests (CBC, CA-125 for ovarian cancer)
Ovarian cystic disease - Treatment
Depends on childbearing status
May drain spontaneously
Surgery might be necessary
Hormonal therapy restoration of progesterone
Polycystic ovary syndrome (PCOS) - now considered what type of disease
A systemic metabolic/hormone disorder
Polycystic ovary syndrome (PCOS) - epidemilogy
Affects 20% of women in US with 50% being obese
Most common cause of infertility - 75% have some degree of it
Polycystic ovary syndrome (PCOS) - s/s
Impaired menstruation
glucose intolerance
Inc risk for type 2 diabetes, fibrocystic breasts, heart disease
Ovarian cancer - epidemiology
5th most common cancer in W
accounts for 90% of deaths related to gyn cancers
Metastatic disease in 60-70% at time of diagnosis
Peak incidence is 40-70 years (half of cases in women over 65)
Ovarian cancer - risk factors
Family hx of breast, ovarian, colon ca Personal hx of breast or endometrial cancer Nulliparity Never breast fed Presence of BRCA-1 or BRCA-2 mutation
Ovarian cancer - s/s
Early CA has no presentation and there is no screening tool
Symptoms of metastasis = unexplained weight loss, pleurisy, ascites
Ovarian cancer - treatment
Surgery
Radiation
Chemotherapy
Ovarian cancer - prognosis
Generally poor due to metastasis at diagnosis
Early stage treatment 90% for 5 yr survival rate
Tumor recurrence within 3 yrs after treatment in most women
PT and gyn cancer
Medical tx is geared toward saving a life
PT is geared toward making their saved life worth living!
Generalized strengthening Pelvic floor strengthening Manual therapy for scar Progressive dilator for stretching Pain management
Treatment algorithm - Medical provider treatment
UTI
Pelvic inflammatory disease
Treatment algorithm - PT
Pelvic pain from mm origin (lumbar/SI dysfunction)
Treatment algorithm - Specialized pelvic physical therapist
Pelvic floor mm dysfunction
Painful bladder syndrome
Defecation dysfunction
Dyspareuina
Does my patient need to see a pelvic floor specialist
P with sitting, can't touch it Hx of gyn dysfunction Hx of incontinence that isn't getting better Pelvic pain in brim of pelvis Suspicion that there is more to it Tailbone pain....and more