FEMALE REPRODUCTIVE SYSTEM Flashcards
The function of Female reproductive system
✓ Produces female gametes (role of the ovaries)
✓ Provides environment for fertilization
✓ Holds embryo for complete development until birth
✓ Produces steroidal sex hormones
LE of OVARIES:
simple cuboidal epithelium
Continues with mesothelium and overlying a
dense connective tissue capsule called
TUNICA ALBUGINEA
Parts of ovaries
o Cortex
- Highly cellular connective tissue
- Ovarian follicles
- Very important
o Medulla
-Loose connective tissue and blood
vessels
___________ surrounded by flat cells called follicular
cells to form a non-growing ovarian follicle
PRIMARY OOCYTES
term for Menopause:
atresia
Oocyte + one or more layers of follicular cells within a basal lamina
OVARIAN FOLLICLE
The first ovarian follicle that we’ll see which is located
at the superficial ovarian cortex
Primordial follicle
Single layer of flattened follicular cells
PRIMORDIAL FOLLICLES
→ Release of follicular stimulating hormone (FSH) from
pituitary gland
FOLLICULAR GROWTH AND DEVELOPMENT
LE of Unilaminar primary follicle
→ Simple cuboidal epithelium
LE of Multilaminar primary follicle
→ Stratified cuboidal epithelium
Characteristic feature of Multilaminar primary follicle:
Zona pellucida
- Well vascularized, steroid producing
cells - Secretes Androstenedione (estrogen
precursor)
o Theca interna
- Fibroblasts and smooth muscles
o Theca externa
Cells secrete clear follicular fluid (liquor folliculi)
ANTRAL FOLLICLES
small fluid-filled spaces fuse forming a cavity
Antrum
→ granulosa cells around the oocyte will form a hillock
Cumulus oophorus
→ tightly adhering granulosa cells that immediately surround the zona pellucida
→ Accompany the oocyte when it leaves the ovary during ovulation
Corona radiata
→ Preovulatory follicle
→ Contains a single large antrum
→ Forms a bulge at the ovarian surface
GRAAFIAN/ MATURE FOLLICLES
o Detachment of granulosa cells
o Autolysis of oocyte
o Collapse of zona pellucida
→ Apoptosis
→ Temporary endocrine gland
CORPUS LUTEUM
- large pale staining cells
- Major hormone produced: progesterone
Granulosa lutein cells
- Progesterone (primary hormone) &
androstenedione - small dark staining cells