Female Reproductive System Flashcards

1
Q

Which of the following changes occur during the female orgasm?

-contraction of perineal muscles.
-rhythmic contraction the distal portion of the vagina.
-waves of contraction in the uterus.

A

All 3

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2
Q

Days 6-9 of a typical 28 day uterine cycle would be referred to as?

A

Early proliferative phase

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3
Q

During which of the phases of the ovarian cycle do the flattened follicular cells of the primordial follicles become cuboidal in shape?

A

Follicular phase

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4
Q

Approximately what percentage of ovulations have the potential to give rise to non-identical twins?

A

1 - 2%

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5
Q

During the proliferative phase of the uterine cycle the layer of tissue from which the endometrium regenerates is called the?

A

Basal layer

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6
Q

Which of the following is NOT a function of oestrogen?

-Development of female libido.
-Stimulation of progesterone secretion.
-Development of female secondary sex characteristics.
-Stimulation of follicular development.
-Stimulation of growth.

A

Stimulation of progesterone secretion

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7
Q

Which of the following is/are features of the middle portion of the follicular phase of the ovarian cycle?

  1. Relatively low and stable levels of LH.
  2. Relatively low and stable levels of FSH.
  3. Relatively low and stable levels of progesterone.
A

All 3

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8
Q

The maturation stage of oogenesis is characterised by which of the following?

  1. growth of the primary oocyte.
  2. development of a single layer of flattened follicular cells.
  3. development of an antrum.
A

1 and 2

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9
Q

The highest levels of oestrogen and progesterone and declining levels of LH and FSH are found during which of the following phases of the ovarian cycle?

-Ovulatory phase.
-Early follicular phase.
-Early luteal phase.
-Mid luteal phase.
-Late follicular phase.

A

Mid luteal phase

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10
Q

The cells of the corpus luteum secrete which of the following hormones?

  1. follicle stimulating hormone
  2. oestrogen
  3. progesterone
A

2 and 3

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11
Q

The phase of the uterine cycle that coincides with high levels of secretion of oestrogen AND progesterone by the ovary is the?

A

mid secretory phase

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12
Q

The typical age range during which ovarian cycles start to become anovulatory and menstrual periods become shorter and less frequent is?

A

46-54

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13
Q

The highest number of primary oocytes are present in the human body at which of the following times?

-at menopause
-12 months after puberty
-the fifth month of gestation
-at birth
-just before puberty

A

the fifth month of gestation

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14
Q

Towards the end of the follicular phase of the ovarian cycle, circulating levels of oestrogen gradually increase because of which of the following?

  1. secretion of oestrogen from the corpus luteum.
  2. secretion of oestrogen from the proliferating follicular cells of the dominant mature follicle.
  3. positive feedback of oestrogen onto the hypothalamus and anterior pituitary.
A

Only 2

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15
Q

The hormonal trigger that cause the arteries of the endometrium to go into spasm during the menstrual phase of the uterine cycle is?

-increasing oestrogen levels
-decreasing oestrogen levels
-increasing progesterone levels
-decreasing progesterone levels

A

2 and 4

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16
Q

The initial development of a few primordial follicles into primary follicles typically occurs in the age range?

17
Q

Which of the following interactions is NOT a feature of the luteal phase of the ovarian cycle?

-All of the above ARE features of the luteal phase of the ovarian cycle.
-Oestrogen exerts a positive feedback effect on the anterior pituitary.
-Oestrogen exerts a positive feedback effect on the hypothalamus.
-Progesterone exerts a negative feedback effect on the hypothalamus.
-Progesterone exerts a negative feedback effect on the anterior pituitary.

A

All of the above ARE features of the luteal phase of the ovarian cycle

18
Q

The beginning of the luteal phase of the ovarian cycle is characterised by which of the following features?

  1. a dramatic decline in circulating LH levels.
  2. a dramatic decline if circulating FSH levels.
  3. a dramatic decline in circulating oestrogen levels.
19
Q

Towards the end of the luteal phase of the ovarian cycle, circulating levels of oestrogen and progesterone gradually decline because?

A

The corpus luteum begins to degenerate

20
Q

During which phase of the ovarian cycle does the corona radiata first appear?

A

ovulatory phase

21
Q

The phase of the uterine cycle which coincides with ovulation is the ?

A

proliferative phase

22
Q

What is zona pellucida?

A

In primary and secondary follicles. Prevents cross species fertilisation and triggers acrosome reaction

23
Q

What is difference between primordial follicle and primary follicles?

A

Primordial follicles single layer flat cells, Primary follocles single layer cuboidal cells

24
Q

What is difference between primary and secondary follicles?

A

Secondary has multiple layers of follicular cells and blood filled antrum

25
What happens to secondary follicles that do not become mature follicles?
Degenerate and are atretic follicles
26
Why does corpus luteum have blood cells in its core?
Rupturing of wall of ovary results in blood cells moving to its core
27
What is difference between endometrial glands at proliferative stage and secretory stage?
Are simple tubular glands at proliferative stage. Default non-secretory stage. At secretory stage, endometrium is thickened and endometrial glands extensively branch and have alveoli; extensive proliferation in number of cells which increases surface area
28
Primordial follicles are found at what stage of life?
In ovaries at birth (only 300,000-400,000 surviving at birth). In suspended animation until puberty
29
What is the uterine cycle stages in order?
Menstrual, proliferative, secretory
30
What is ovarian cycle stages in order?
Follicular, ovulatory, luteal
31
What is the corpus luteum?
Glandular body that develops from a mature follicle. Follicular cells of CL secretes progesterone + little oestrogen. If fertilisation does not occur, at end of luteal phase it breaks down to form white scar called corpus albicans. If fertilisation occurs it continues to play important role in pregnancy
32
What phase in the monthly reproductive cycle of females occur simultaneously?
Regression of corpus luteum and decrease in progesterone secretion
33
Why does FSH and LH levels gradually decline during luteal phase?
Formation of corpus luteum means increased progesterone + little oestrogen. The rising oestrogen exerts a positive feedback effect on the anterior pituitary and hypothalamus while progesterone exerts a negative feedback on the same structures. Because the progesterone inhibitory effect predominates, LH and FSH levels tend to gradually decline during the luteal phase.
34
What is hormonal changes during ovarian cycle responsible for single mature follicle to rupture through wall of ovary, expelling it's oocyte?
Negative feedback by oestrogen during follicular phase suddenly become a positive feedback loop. Instead of inhibiting the hypothalmus and anterior pituitary, oestrogen now stimulates these structures and so we see a rapid increase in circulating levels of FSH and LH. The sudden peak in LH (LH surge) is the trigger for ovulation at around day 14 of the cycle. After ovulation estrogen levels begin to decline due to the damage done to the mature follicle following ovulation.