Female Reproduction 1 Flashcards
Ovarian Cycle also known as
Menstrual cycle
Define Menarche
the FIRST menstrual period in a female adolescent.
What consists of the FEMALE REPRODUCTIVE CYCLE
- Ovarian cycle
- Uterine or Endometrial cycle
- Menstruation
- Menopause
Ovarian Cycle consists of
- Follicular phase (FSH & LH)
- Ovulation
- Luteal phase
What is FSH? What does it do?
- Follicle-stimulating hormone (FSH) released by the pituitary gland
- FSH is primarily responsible for stimulating the ovaries to secrete estrogen.
What is LSH and what does it do?
- luteinizing hormone (LH)
- LH is primarily responsible for stimulating progesterone production.
What to know about the LUTEAL PHASE
- Under the combined stimulus of estrogen and progesterone, the endometrium reaches the peak luteal phase, in which the endometrium is thick and highly vascular.
- In the luteal phase, which begins after ovulation, progesterone is secreted by the corpus luteum.
Uterine or Endometrial cycle:
Explain Proliferative Phase
- in the BEGINNING OF THE CYCLE just AFTER MENSTRUATION.
- It is the enlargement of endometrial glands.
- Cervical mucus becomes thin, clear, stretchy, & more alkaline
- Starts about D5 of menstrual cycle
- Lasts till time of ovulation.
Uterine or Endometrial cycle:
Explain Secretory phase
- near the middle portion of the cycle (day 14 in a 28-day cycle)
- Ovulation to 3 D before menses
– endo thick, glandular, vascular
- LH output increases and ovulation occurs.
Uterine or Endometrial cycle:
Explain ischemic phase
- Consists of Progesterone & Estrogen
- Arteriole spasms
– Rupture of arterioles
EXPLALIN ‘MENSTRUATION’
Sloughing & discharge of lining of uterus
- If NO conception
- Q 28 D in reproductive yrs.
- Lasts 4-5 D
- Avg menarche 12.8 yrs. (U.S.) (genetics plays a role)
Cultural & Psychosocial Considerations for MENSTRUATION
Nurse needs to …
*Be open-minded
*Educate in a culturally sensitive manner
*Convey confidence & openness
Menstrual Disorders
- PERIMENOPAUSE
- MENOPAUSE
What is Menopause?
- The stage of life that marks the PERMANENT cessation of menstrual activity.
- Usually occurs between ages 45-55.
- It is a natural biological process.
2 STAGES of Menopause.
Name them
- Perimenopause
- Menopause
When does Perimenopause occur?
2-8 years BEFORE menopause
-As early as age 38
- possible for women to become pregnant.
When does Menopause occur?
50-51
S/S of PERIMENOPAUSE
*Hot flashes
*Night sweats
*Irregular menstrual cycles
*Sleep disruptions
*Fatigue
*Forgetfulness
*Mood disturbances, Depression, *Irritability
*Decreased fertility
*Weight gain & bloating
*Changing bleeding patterns
*Headaches
*Decreased vaginal lubrication
*Vaginal atrophy
S/S of Menopause
Vasomotor symptoms:
*Sensations of heat, cold sweating
*Headache
*Insomnia and irritability
Physiologically
*Vaginal dryness, irritation, & itching
*Dyspareunia
*Dysuria
*Urinary frequency & urgency
What to look for when DX menopause
age
symptoms (R/O other conditions)
elevated serum FSH (>40 mIU/mL
Menopause SYMPTOM TX:
Lifestyle changes examples
- Get 8 hours of sleep per night,
- Eat a balanced diet- decrease fat and caloric intake; increase intake of whole grains, fiber, fruit, and vegetables.
- Consider weight-bearing exercises, calcium (1000-1200mg), vitamin D (400-600IU), vitamin E (100 mg daily), smoking cessation, and avoidance of alcohol to treat or prevent osteoporosis.
- Regular breast examinations and mammograms are essential. Local estrogen creams can be used for vaginal atrophy.
- Exercise-reduces stress, enhances well-being, improves self-image
- Avoid caffeine and alcohol
- Avoid cigarette smoking and secondhand smoke-lower risk of heart disease
Menopause SYMPTOM TX:
examples of Alternative medicine OR Complementary and Alternative Medicine (CAM)
*Black cohosh, dong quai
*St. John’s wort, hops
*Wild yam, ginseng
*Evening primrose oil
*Acupuncture, Aromatherapy
*Reflexology, Meditation
Menopause SYMPTOM TX:
Pharmacologic options
- HT unless contraindicated
- Estrogen and androgen combinations
- Progestin therapy (Depo-Provera injection every 3months)
- Clonidine - anti-HTN (central alpha-adrenergic agonist) weekly patch
- Propranolol (beta-adrenergic blocker)
- Brisdelle: FDA-approved nonhormonal medication
- Short-term sleep aids: Ambien, Dalmane
- Gabapentin (Neurontin): antiseizure drug
- SSRIs: venlafaxine (Effexor) and paroxetine (ANTIDEPRESSANTS)
Menopause SYMPTOM TX:
HORMONTE THERAPY OPTIONS
- Estrogen alone - NO uterus
- Combo - Lowers risk of endometrial ca
- Progestin Only - Depo
Menopause SYMPTOM TX:
Contraindications for patients who have
H/O breast cancer
Vascular thrombosis
Impaired liver function
Uterine cancer
Abnormal vaginal bleeding
Role of Nurse for Menopause patients
- Recognize & Analyze Cues (Assessment & Dx)
- Hypothesis (Patient problems)
- Altered sleep, Irritable or Depressed mood, Thinning bones, Low libido, Low self-esteem, Muscle & joint pain, Excess sweating, Skin dryness, Painful sexual intercourse, Anxiety, Hot flashes, Mood swings - Solution (Goal or Plan)
- Actions (Interventions)
- Primary Prevention (Education & counselling - R/T preventable conditions due to menopause)
- Secondary Prevention (Screening)
- Tertiary prevention Prevention (Manage to slow progression or stop) - Evaluation (Outcomes)
NAme The 5 COMMON MENSTRUAL DISORDERS
- Menopause/Perimenopause
- Irregular Periods
- Endometriosis
- Abnormal Uterine Bleeding (AUB)
- Premenstrual syndrome (PMS)
- Premenstrual dysphoric disorder (PMDD)
What are the 9 types of Irregular periods
- *Amenorrhea - ‘NO’
- *Oligomenorrhea (Infrequent)
- *Polymenorrhea (Frequent)
- *Hypomenorrhea - Light
- *Metrorrhagia - Heavy
- *Menorrhagia - Spotting
- *Dysmenorrhea - Painful
- *Anovulation – NO
- *Oligoovulation – irregular or infrequent
Type of Irregular period:
Absence of periods
Amenorrhea
Type of Irregular period:
Infrequent periods (long cycles)
Oligomenorrhea
Type of Irregular period:
Frequent periods (short cycles)
Polymenorrhea:
Type of Irregular period:
Light periods
Hypomenorrhea
Type of Irregular period:
Spotting between periods
Metrorrhagia:
Type of Irregular period:
Painful periods
Dysmenorrhea:
Type of Irregular period:
Absence of ovulation
Anovulation:
Type of Irregular period:
Irregular or infrequent ovulation
Oligoovulation:
Define:
The absence of menstrual flow, is a symptom of a variety of disorders and dysfunctions.
Amenorrhea
There are 2 types of Amenorrhea
Primary Amenorrhea
Secondary Amenorrhea
Types of Amenorrhea:
WHICH ONE AM I?
- Delayed Menarche
- Situation where a young woman who by age 15 yrs : Absence of menses and has NOT began to development secondary sexual characteristics
or
- Who by age 16 years or older who has NOT developed either secondary sex characteristics NOR started menstruations (menses).
PRIMARY Amenorrhea
Causes of PRIMARY AMENORRHEA
- Genetic
- Systemic –
- Wt. – gain/loss
- Chronic stress
- Hypothyroidism
- CNS disease - Turner Syndrome
- Anorexia
- Other - Drug abuse
Type of Amenorrhea:
WHICH ONE AM I?
an absence of menses for three cycles OR 6 months after a normal menarche
SECONDARY AMENORRHEA
Causes of SECONDARY AMENORRHEA
may be caused by:
- functional hypothalamic amenorrhea
- pituitary disease
- primary ovarian failure
- pregnancy
- breast-feeding
- menopause
- too little body fat (about 22% required for menses)
- eating disorder: OBESITY OR MALNUTRITION
- thyroid disease
- polycystic ovary syndrome
- Chemotherapy
Diagnostics for BOTH primary and secondary Amenorrhea
*US-(ULTRA SOUND) -Cyst
*Quantitative hCG
*Thyroid Function
*Prolactin level
*Increase FSH (Ovarian) & LH level (Gonadal dysfunction)
*Increase 17-ketosteroids (adrenal tumor)
Management (RX) for Primary Amenorrhea
Name 3.
- Correct abnormalities
- Estrogen HRT - dev. of sec. sex characteristics
- Educate patient
Management (RX) for Primary Amenorrhea
- R/O (Rule out) pregnancy (HCG Test)
Education & Counseling
**Anovulation **- Cyclic progesterone or OCs
Bromocriptine** - hyperprolactinemia
**Nutritional- anorexia, bulimia, or obesity
GnRH -** Depo-Provera q 3 M
**Thyroid replacement – hypothyroidism
Define:
- Abdominal cramping or discomfort with menstrual flow
- is thought to result from excessive production of prostaglandins, which causes painful contraction of the uterus.
Dysmenorrhea
Dysmenorrhea:
Which phase is:
- SPASMODIC
- No identifiable pelvic pathology
- Increase prostaglandins
Primary Dysmenorrhea
Dysmenorrhea:
Which phase is:
- Congestive
- Related to pelvic pathology - these contribute to symptoms
Secondary Dysmenorrhea
Secondary Dysmenorrhea’s Pelvic pathology include
- Endometriosis
- Endometrial polyps
- Fibroids or PID (Pelvic inflammatory disease)
- Congenital Abnormalities
S/S for Dysmenorrhea
- Onset of menses – last 48-72 hrs
- Painful uterine cramping
- Lower abd pain – may radiate to low back, thighs
- GI S/S – n/v, bloating, diarrhea
- Nervousness, HA, syncope
- Breast tenderness
Diagnostic Studies to ID structural abnormalities, hormone imbalances and pathological conditions in DYSMENORRHEA
*CBC, UA, ESR, HCG
*Cervical culture to exclude STI
*Stool guaiac
*Pelvic and/or vaginal ultrasound
*Diagnostic laparoscopy and/or laparotomy
Nursing Management for Dysmenorrhea
*Prevention
*Education & support
*Medications - NSAIDS & Low-dose OCPs
*Nutrition - B6, Ca, Mg, protein
*Exercise
*Heat
*Biofeedback, hypnosis, relaxation
*Dietary or herbal supplements
What is Abnormal Uterine bleeding (AUB)?
- irregular, painless bleeding of endometrial origin that may be excessive, prolonged, or without pattern.
- Dysfunctional uterine bleeding can occur at any age but is most common at opposite ends of the reproductive lifespan.
- It is usually secondary to anovulation (lack of ovulation) and is common in adolescents and women approaching menopause.
*NO known cause or systemic disease
* R/T hormonal Disturbances
What are Causes for Abnormal Uterine Bleeding (AUB)
Remember PALM COEIN:
PALM (structural)
- polyp
- adenomyosis
- leiomysosis
- Malignancy
COEIN (other)
- coagulopathy
- Ovulatory dysfunction
- Endometrial
- Latrogenic
- Not yet classified