Female repro anatomy Flashcards
Location of the ovaries?
Lie adjacent to proximal ends of uterine horns
Are attached to broad ligament
Two functions of the ovaries
Production of gametes and hormones
Ovary structure
Outer cortex:
- Collagen fibres provide support (ovarian stroma)
- Ovarian parenchyma (follicles and various interstitial cell types)
Central medulla:
- Blood vessels
- Lymphatics
- Nerves
- Connective tissue
Follicle contains
1 oocyte + surrounding follicular cells
Stages of follicular development
- Primordial follicle
- Primary follicle
- Secondary follicle
- Tertiary follicle
- Antral follicle
- Ovulating follicle
- Corpus luteum
- Corpus albicans
Primordial follicles
One layer of flattened follicular cells surrounding oocyte
Form before the female is born - further development does not occur until puberty
Primary follicle
Onset of follicular maturation (develop as soon as the animal starts to be reproductive)
Flattened cells now form cubodial epithelium (also called granulosa cells)
Zona pellucida becomes visible
Zona pellucida
Glycoprotein coat surrounding oocyte designed to prevent polyspermy
Secondary follicle
Follicles with straified epithelium, enclosing oocytes with a distinct zona pellucida
Small fluid-filled spaces become visible between granulosa cells
These spaces will fuse to form antrum
Thecal cells: epitheliod cells outside follicle intermeshed with stroma - form a wall around follicle - start to produce oestrogen - stimulates follicle to keep growing
Tertiary follicle
Follicular epithelium produces fluid
Eventually forms an antrum
Antrum follicle
Increases further in size
Oocyte floats in antrum
~12h before ovulation a small ‘bump’ forms on surface of the follicle (stigma)
Follicle ruptures at stigma and oocyte released
Ovulating follicle
Follicle ruptures at stigma and oocyte is released
Emptied follicle filled with blood
Wall of follicle collapses & folds in
Cell lutenization and proliferation occurs
(blood in follicle only lasts about 12 hours)
Corpus Luteum
Vascularisation
Cell differentiation
Endocrine organ - progesterone
Very large relative to ovary
- If the egg is fertilized corpus luteum remains and produces progesterone to support pregnancy
Corpus Albicans
Scar from old corpus luteum
The wall of the entire female genital tract consists of 3 concentric layers:
- Mucosal tunic (inner tunic)
- Muscular tunic (middle tunic)
- Serosal (outer tunic)
Mucosal tunic (female repro tract wall)
Inner tunic
Forms longitudinal folds in oviduct and non-gravid uterus
Muscular tunic (female repro tract wall)
Middle tunic
Two muscle layers, inner circular and outer longitudinal layer separated by a highly vascular layer
- help move sperm and ova via muscle contraction
Serosal tunic (female repro tract wall)
Outer tunic -
composed of peritoneum, covering surface of oviduct
Infundibulum
- Thin-walled funnel cranial extremity of oviduct
- Free-edge of funnel ragged & tags (fimbriae) come into contact with ovary
- Captures ovum
- Finger-like projections catch the egg
Uterine tube/ Oviduct
- Narrow and flexuous tube
- Fertilisation occurs in oviduct
- Joins apex of horn of uterus at uterotubal junction
Uterus
Y-shaped (bicornuate) with paired uterine horns in domestic species
Consists of:
- Uterine horns
- Body (usually quite small)
- Cervix (thick walled)
3 layers lining uterus:
- Endometrium (mucosal layer) - Uterine glands present - provide nourishment for early embryo
2 .Myometrium (fibromuscular layer)
- Serosal layer
In ruminants, the endometrium of the uterus is marked with numerous permanent elevations called….
Caruncles
- mark the sites of embryonic attachment