Female Hormonal System Flashcards
The female hormonal system like that of male consist of three hierarchies of hormones
1a hypothalamic releasing hormone gonadotropin releasing hormone
2 interior pituitary sex hormones follicles stimulating and lutinizing hormone
3 the ovarian hormones estrogen and progesterone
What are the two significant results of the female sexual cycle
1 only a single ovum is normally released from the ovaries each month
2 uterine endometrium is prepared in advance for implementation of the fertilized over at the required time of the month
What is the main function of estrogens
The estrogens mainly promotes proliferation and growth of specific cells in the body that are responsible for the development of most secondary sexual characteristics of the female
What is the main function of progesterone
Progester and functions mainly to prepare the uterus for pregnancy and the breast for lactation
Name the three estrogens that are present in significant quantity in the plasma of the human female
Beta estradiol, estrone and estriol
The principle oestrogen secreted by the ovaries is
Beta estradiol
what do you know about estrone?
It is one of the estrogen that is released in a small quantity from the peripheral tissues from androgens secreted by the adrenal cortex and by the ovarian thecal cells
It’s potency is 12 times less than beta estradiol
What is estriol?
It is a weak estrogen and oxidative product dry from both esterodial and estrone with the conversion occurring mainly in the liver it has potency 80 times less than beta estradiol
Name and other progestering that is secreted along with progesterone
17 alpha hydroxyprogesterone
Estrogens and progesterons are synthesized by
These are synthesized from cholesterol drive from the blood but also to a slide extent from the acetyl co enzyme a multiple molecules of which can combined to form the appropriate steroid nucleus
How much testosterone is secreted into the plasma of the female
All about one- fifteenth as much testosterone is secreted into the plasma of the female by the ovaries as a secreted into the plasma of the male by the testes
How much testosterone is secreted into the plasma of the female
All about one- fifteenth as much testosterone is secreted into the plasma of the female by the ovaries as a secreted into the plasma of the male by the testes
How both estrogen and progesterones are transported in the blood
Estrogens and progesterones are transported in the blood bound mainly with plasma albumin and with specific astrogen and progesterone binding globulins
How liver helps in estrogen degradation
The liver conjugates the estrogens to form glucuronides and sulphates. About one fifth of these conjugated products is excreted in the bile most of the reminder is excreted in the urine.
Also the liver Converts the potent oestrogens estradiol and estrone into the almost totally important estrogen estriol