Feline Viruses 2 Flashcards
What does FHV stand for?
Feline herpes virus (Type 1)
Where is FHV found?
World wide
What kind of virus if FHV?
Herpes, DS DNA, enveloped (therefore has latency period)
Explain the transmission of FHV
Is there a vx for FHV?
Yes part of FVRCP vx but apparently doesn’t work great
What are the clinical signs of acute FHV?
feline rhinotacheitis, conjunctavitus, superficial & deep corneal ulcers, dendritic ulcers, sneezing, nasal discharge
Clinical signs of chronic FHV?
Stromal keratitis, chronic rhinosinustis, can lead to blindness, chronic sneezing and nasal discharge
What is the incubation period of FHV?
2-6 days
What feline viruses affect the respiratory tract?
FHV and FCV
What does FCV stand for?
Feline Calici virus (not feline corona virus!!)
What type of virus if FCV?
small ssRNA RNA virus, non enveloped, there for there is a lot of strains
How does FCV spread?
Predominantly via oral and nasal discharge in the ACUTE phase
Explain the transmission of FCV
How long do cats shed when they hav FCV?
Cat will continue shedding past clinical signs most of them shed for at least 30 days post infection and a few for several years up to life long
Where is FCV spread ?
Widespread
What are the clinical outcomes of FCV?
- Acute oral and upper respiratory tract disease
- Feline chronic gingivostomatitis (FCGS)
- Limping syndrome
- Paw and mouth disease (only in Australia)
- Virulent systemic feline calicivirus (VS-FCV)
infection
What is one way to tell FCV acute oral and upper respiratory tract disease from FHV?
ORAL ULCERS
FCV acute oral and upper respiratory tract disease often _________, with _____, ______, or __________
co-infections with FHV, Chlamydia felis or
Mycoplasma felis
What age cats are most likely infected by FCV acute oral and upper respiratory tract?
YOUNG
How do you treat FCV acute oral and upper respiratory tract?
Usually self limiting and resolve within a few days, only symptomatic treatment is needed
What is FCV Feline chronic gingivostomatitis?
Caudal stomatitis must be identified in order to diagnose FCGS
What is FCV limping syndrome? And when can it occur?
Lameness associated with acute viremia and localization of virus and/or immune complexes in joints. Lasts 24-48 hours and can shift between legs
Can occur following vaccination or infection
What is paw and mouth disease?
Erosion of paw pads and inflammation if the interdigital areas. Probably a milder form of VS-FCV. Only described in Austrailia
What is VS-FCV?
Facial edema (vasculitis), hair loss, systemic crusted lesions, paw lesions
What are the implications of VS-FCV?
High mortality (70%), strand that causes this is not the same common resp FCV, vaccine may not be protective
Is there a vaccine for FCV?
Yes, part of FVRCP vx
What type of infection is panleukopenia?
Systemic
What type of virus is panleukopenia?
ssDNA, non enveloped, Parvo virus.
Therefore also called feline Parvo virus (FPV)
Where does panleukopenia replicate?
lymphoid tissues (thymus, spleen, bone marrow) and other rapid dividing cells: intestine, bone marrow, and in embryonic tissue.
Is panleukopenia stable?
Yes very stable in the environment! B/c non enveloped , can stay in environment for unto 6 months
If pregnant cats get infected with panleukopenia what happens?
FPV antigen is present in the cerebellum of kittens for weeks, causing cerebella hypoplasia
What is different about panleukopenia and FHV and FCV?
Persistent infections and persistent viral shedding are rare
Explain the possible pathological outcomes of panlleukopenia
What are the clinical signs of panleukopenia?
-hemorrhagic enteritis
-Segmental hyperaemia
-Intestinal damage/ sloughing of gut epithelium with fibrinous casts
-(Same GI signs as dogs)
-Dehydrated
-Cerebella hypoplasia (leading to neurological signs)
Is there a vx for panleukopenia?
Yes part of FVRCP, works very well
What is H5N1?
High pathogenic avian influenza
How doe cats get infected with H5N1?
By eating an infected bird
What H of influenza can infect cats?
H5
How can cats get infected with cow pox?
Through eating rodents, therefore outdoor cats. no aerosol transmission has to touch lesion
Where is feline cowpox found?
Mainly in Europe, not in North America
What feline virus is zoonotic? What does it lead to?
Feline cowpox, can lead to necrotising ulcers and lymphadenitis
How do you treat feline cowpox?
Typically self limiting, but can go systemic, causing pulmonary cowpox
Sars-CoV-2/ COVID 19 is what kind of virus?
enveloped ss+ RNA virus, corona virus
What clinical signs do cats infected with Sars-CoV-2 have?
None but they produce a lot of virus
Who can cats transmit Sars-CoV-2 to?
- cat-to-cat
- Human to cat transmission
- Cat to human transmission not demonstrated (although likly possible)