Feedback Mechanisms Flashcards
Negative feedback causes…
Corrective measures brought about by effectors to be turned off, system is returned to normal level
Positive feedback causes…
The corrective measures to remain turned on, system deviates further from norm
What are the 4 main hormones involved in the menstrual cycle
LH
FSH
Oestrogen
Progesterone
What happens during days 1-5 of menstrual cycle?
The uterus lining is shed, along with blood
What does FSH cause?
- growth and maturation of follicle that contains egg
- stimulates oestrogen
What does oestrogen do?
- causes uterus lining to build up
- inhibits release of FSH and LH from pituitary gland
When oestrogen reaches a critical level (day 10), what happens?
Stimulates pituitary gland to release more FSH and LH
What does LH do?
- causes ovulation (day 14)
- stimulates empty follicle to develop into corpus luteum which secretes progesterone
What does progesterone do?
- maintains thick lining of uterus in readiness of egg
- inhibits production of FSH and LH
What happens if the egg is not fertilised?
- the corpus luteum degenerates, so less progesterone is released
- uterus lining breaks down (menstruation)
- this means production of FSH and LH is no longer inhibited, therefore cycle repeats
What is an example of positive feedback in menstrual cycle?
- when oestrogen reaches critical level, it causes further secretion of FSH and LH
What is an example of negative feedback in menstrual cycle?
- progesterone inhibits further release of FSH and LH
- oestrogen inhibits FSH and LH