FBC Flashcards
What is Erythropoiesis?
The production of red blood cells in the bone marrow , stimulated by erythropoietin.
What is Thalassaemias?
A genetic disorder characterised by deficient production of alpha & beta globin chains.
Results in low haemoglobin and anaemia.
What is Polycythaemia?
Raised red blood cell count.
What is so Polycythaemia Vera?
Over production of red & white blood cells.
What may cause raised RBC.
- Smoking
- Dehydration
- Living at high altitudes
- Airway disease
What is the term for raised mean cell volume?
Macrolytic
What is the term for reduced mean cell volume?
Microlytic
What is thrombocytosis?
Increased platelet count
What is thrombocytopenia?
Reduced platelet count
What drugs may cause thrombocytopenia?
- Heparins
- Anticonvulsants
- Quinine & Quinidine
- Diuretics
- NSAID’s
- Sulfonamides
What is leucopenia?
Decreased white cell count
What drugs may cause leucopenia?
- Carbimazole
- Methotrexate
- Chemotherapy
What are C-reactive proteins?
A protein secreted by the liver in response to inflammatory cytokines which activates the immune response.
Name two cardiac markers.
- Troponins
- Creatinine Kinase
What is the equation for INR?
INR = Patient PT ÷ Control P
