Fatty Acids: Synthesis and Oxidation Flashcards
1
Q
FA Synthesis
A
synthesis occurs in the cytoplasm from AcCoA that is transported out of the mitochondria
2
Q
Beta Oxidation
A
occurs in the mitochondria following transport by the carnitine shuttle
3
Q
What is the only FA that humans can synthesize?
A
Palmitic acid
4
Q
Rate limiting enzyme of FA synthesis and function?
A
AcCoA carboxylase - requires ATP and biotin, activates AcCoA in the cytoplasm for incorporation into FA’s by adding CO2 to AcCoA to form malonyl-CoA
5
Q
5 steps in FA synthesis
A
- Activation - via AcCoA carboxylase
- Condensation
- Reduction
- Dehydration
- Reduction
