FAT SOLUBLE VITAMINS (VITAMIN A, D, E, K) Flashcards
Visual adaptation to light and darkness
VITAMIN A: RETINOL
Handling and preparation losses are seen with heating
DIETARY SOURCES OF VITAMIN A: RETINOL
DIETARY SOURCES OF VITAMIN A: RETINOL
- Handling and preparation losses are seen with heating
- Fruits and vegetables (dark green and deep orange)
- Animal sources (fish, liver oils, butter, eggs, fortified milk products)
What are the RDA (VITAMIN A: RETINOL) for:
FEMALE =
RDA FOR FEMALE: 700 ug RAE/day
What are the RDA (VITAMIN A: RETINOL) for:
MALE =
RDA FOR MALE: 900 ug RAE/day
VITAMIN A: RETINOL is also measured in ___
IU
Four (4) DEFICIENCIES of VITAMIN A: RETINOL
*NIGHT BLINDESS
*KERATINIZATION
*XEROPHTHALMIA
*KERATOMALACIA
Lack of vitamin A at the back of the eye in the retina; major cause of childhood blindness in the world
NIGHT BLINDESS
Changes in cell structures throughout the body that result in hard, inflexible skin due to secretion of protein keratin
KERATINIZATION
Lack of Vitamin A at the front of the eye that affects the cornea and can lead to total blindness
XEROPHTHALMIA
Softening of the cornea occurs, leading to blindness that is irreversible
KERATOMALACIA
EXCESS of VITAMIN A: RETINOL
- SYMPTOMS: HEADACHE, VOMITING, WEIGHT LOSS TO BIRTH DEFECTS AND BONE ABNORMALITIES
- TERATOGENIC EFFECTS
- YELLOWING OF SKIN
Healthy skin and mucous membranes depend in part on adequate amounts of _____
VITAMIN A: RETINOL
Regulate cell differentiation associated with reproduction and the immune response
VITAMIN A: RETINOL
___ metabolites exist in the body and are used to synthesize this vitamin, unlike other vitamins
VITAMIN D: CALCIFEROL
Regulation of calcium and phosphorus in the body
VITAMIN D: CALCIFEROL
Regulation by the kidney and parathyroid glands helps maintain _______ balance
VITAMIN D: CALCIFEROL
Sunlight activation enables _____ synthesis in the skin
VITAMIN D: CALCIFEROL
____ also works with other vitamins (__,___,__) hormones and minerals to affect bone growth
VITAMIN D: CALCIFEROL
VITAMIN (A, C, K)
DIETARY SOURCES of VITAMIN D: CALCIFEROL
- Found naturally in fish, liver and oils
- Fortification of dairy products
- Handling and preparation losses are seen with heating
What are the RDA (VITAMIN D: CALCIFEROL) for:
MALE =
MALE = 5ug/day
What are the RDA (VITAMIN D: CALCIFEROL) for:
FEMALE =
FEMALE = 5ug/day from 19-50 years
Four (4) DEFICIENCIES of VITAMIN D: CALCIFEROL
- RICKETS
- OSTEOMALACIA
- DEVELOPMENT OF OSTEOPOROSIS
- ASSOCIATED OF OSTEOPOROSIS
Clinical deficiency state affecting children that results in structural deformities (bowed legs and pigeon breast) due to poor bone mineralization and growth retardation
RICKETS
Clinical deficiency state affecting adults that result in bone weakness, fragility and increased bone fractures
OSTEOMALACIA
Vitamin D deficiency can lead to development of osteoporosis in conjunction with calcium losses
DEVELOPMENT OF OSTEOPOROSIS
Intestinal, liver or PTH hormone disorders, chronic pancreatitis, or renal disorders
ASSOCIATED OF OSTEOPOROSIS
______ is the clinical excess state that is associated with calcium deposits, growth retardation and kidney damage
Hypervitaminosis D
EXCESS of VITAMIN D: CALCIFEROL
Associated with increased levels of calcium that can upset hormone balance and result in endocrine dysfunction
Antioxidant Properties
VITAMIN E: TOCOPHEROL
Protects all cell membranes
VITAMIN E: TOCOPHEROL
Synergistic Effects
VITAMIN E: TOCOPHEROL
Effect on oxygen and blood exchange
VITAMIN E: TOCOPHEROL
What are the RDA (VITAMIN E: TOCOPHEROL) for:
FEMALE =
FEMALE = 15MG/DAY
What are the RDA (VITAMIN E: TOCOPHEROL) for:
MALE =
MALE = 15MG/DAY
HANDLING AND PREPARATION LOSSES ARE SEEN IN COOKING AND OXYGENATION
VITAMIN E: TOCOPHEROL
4 (FOUR) DEFICIENCIES of VITAMIN E: TOCOPHEROL
- Erythrocyte hemolysis
- Immunosuppressed or with fat malabsorption e.g. Cystic Fibrosis
- Fertility and sterility issues
- Neurological and muscular symptoms
EXCESS of VITAMIN E: TOCOPHEROL
- Impairment of Absorption of other fat-soluble vitamins
- High doses may potentiate anticoagulant effects of sodium warfarin
Belong to a family called quinones
VITAMIN K: MENADIONE
Clotting cascade—production of prothrombin—thrombin; fibrinogen-fibrin
VITAMIN K: MENADIONE
Affects clotting factors (II, VII, IX and X) in the liver and is measured by PT
VITAMIN K: MENADIONE
Bacteria in the intestines: synthesize vitamin K; requires bile acids to effectively function in the body
VITAMIN K: MENADIONE
Newborns require Vitamin K injection at birth
VITAMIN K: MENADIONE
Antagonist to the action of Warfarin
VITAMIN K: MENADIONE
THREE (3) DEFICIENCIES of VITAMIN K: MENADIONE
- Hemorrhagic Disease of the Newborn
- Liver disease and fat malabsorption
- Clients with long term antibiotic therapy: at risk for deficiency
DIETARY SOURCES of VITAMIN K: MENADIONE
- Dark green leafy vegetables
- Cabbage, Milk
- Bacterial synthesis in the intestines
What are the RDA (VITAMIN K: MENADIONE) for:
FEMALE =
FEMALE = 90 ug/day
What are the RDA (VITAMIN K: MENADIONE) for:
MALE =
MALE = 120 ug/day
What are the EXCESS of VITAMIN K: MENADIONE
- Anemia in Newborn (Along with Jaundice)
- Blood clotting and release of bilirubin into the circulation can lead to toxic levels and possible brain damage
What are the SIX (6) MAJOR MINERALS?
- SODIUM
- CHLORIDE
- POTASSIUM
- CALCIUM
- PHOSPHOROUS
- MAGNESIUM
What are the TWO (2) MINOR (TRACE) MINERALS?
- IRON
- IODINE
Pertain to the elements in their simple inorganic form.
MINERALS
They are commonly referred to as mineral elements or trace minerals if required in small amounts
MINERALS
Involved in fluid balance via antidiuretic hormone and aldosterone secretion
IRON
Nerve transmission and neurological function (THINK BRAIN!) - critical for brain health)
IRON
Maintain acid base balance in conjunction with chloride
IRON
MAJOR CATION OF ECF (extracellular fluid). While major cation in the intracellular fluid is potassium.
IRON
What is the RDA (IRON):
ADULTS:
ADULTS: 500 mg/day
Another RDA of (IRON)
Clients be instructed not to routinely add salt to foods during cooking process
DIETARY SOURCES of IRON
- Processed or prepared foods
- Preservative or flavoring agent in food products (salts etc)
- Hidden sources (Medications)
FIVE (5) DEFICIENCIES of IRON
SYMPTOMS
1. Nausea
2. Vomiting
3. Diarrhea
4. Muscle Cramps
5. Mental Status Changes (Confusion & Disorientation)
EXCESS of IRON
- Hypernatremia
- Contributes to the development of edema and hypertension and lead to neurological signs
Fluid balance; major anion of the ECF
CHLORIDE
Acid base balance and moves across the cell membrane to interact with potassium
CHLORIDE
Maintain gastric acidity (HCL)
CHLORIDE
TWO (2) DEFICIENCIES of CHLORIDE
- Infants with condition of failure to thrive
- Losses occur through GI tract and result in dehydration and acid base imbalance
RDA of CHLORIDE
- 750 mg/day
- Often linked with sodium in foods
What are the EXCESS of CHLORIDE?
- Vomiting
- Not usually seen unless there is an underlying disease state
It help rid your body of salt (sodium) and water. Can decrease edema and blood pressure.
DIURETICS
Important in nerve transmission and muscle contraction
POTASSIUM
Maintain acid base balance by transcellular shifting in response to acid base changes in the body
POTASSIUM
Cardiac muscle (THINK HEART!)
POTASSIUM
MAJOR CATION OF THE ICF
POTASSIUM
DIETARY SOURCES of POTASSIUM
- Cooked dried beans, potatoes, banana, orange
- Fresh fruits, less in processed foods
- Large amounts of licorice in the diet can lead to hypokalemia and sodium water retention
What are the FOUR (4) DEFICIENCIES of POTASSIUM?
- Seen coexisting with deficiencies of other electrolytes (magnesium and calcium)
- Do not usually rise from dietary factors
- Seen usually from the use of certain medications that promote K+ excretion (LOOP DIURETICS – furosemide (Lasix))
- Can potentiate drug actions as in the case of digitalis toxicity
What are the TWO (2) EXCESS of POTASSIUM?
- Do not usually arise from dietary ingestion unless clients use salt substitutes or k+ supplements
- Certain medications can lead to retained levels of potassium in the body such as ace inhibitors, steroids, and potassium sparing diuretics (spironolactone (Aldactone))
RDA of POTASSIUM
ADULTS: 2000 MG/DAY
Constituent part of bones and teeth
CALCIUM
Nerve conduction (neurotransmitter) and muscle contraction (actin/myosin)
CALCIUM
Coagulation pathway
CALCIUM
Active and inactive forms exist in the body (ionized and nonionized)
CALCIUM
Phosphorus – inverse relationship
CALCIUM
PTH (parathyroid hormone) – increases serum ca+
CALCIUM
CALCITONIN – decreases s. Ca+
CALCIUM
What are the EIGHT (8) DEIFICIENCIES of CALCIUM?
- PHYTATES – decreases calcium absorption (nuts, seeds, grains)
- OXALATES – decreases calcium absorption (spinach, beets, chocolate)
- HIGH FIBER – decreases Ca+ absorption
- Clinical signs: CHVOSTEK (facial nerve grimace) and
TROUSSEAU (carpopedal spasm) - Associated deficiencies seen with potassium and magnesium
- Development of tetany
- Osteoporosis
- Bone demineralization, relaxed nerve and muscle coordination
decreases calcium absorption (nuts, seeds, grains)
PHYTATES
decreases calcium absorption (spinach, beets, chocolate)
OXALATES
decreases Ca+ absorption
HIGH FIBER
(facial nerve grimace)
CHVOSTEK
(carpopedal spasm)
TROUSSEAU
DIETARY SOURCES of CALCIUM
- Sardines, milk, dairy
RDA of CALCIUM
- AI = 1000 mg/day for adults (19-50 yo) 1500 mg/day for adults 51 years and over
FOUR (4) EXCESS of CALCIUM
- Metastatic process or kidney stone formation
- Constipation
- MILK-ALKALI SYNDROME - alkalotic condition due to increased amounts of milk or antacid
- Hypercalcemic crisis