Fat Metabolism

Question 1

Adiponectin?

Answer 1

1. Hormone released by adipocytes.
2. Increases insulin sensitivity.
3. Increases fatty acid oxidation.
4. Inverse relationship to obesity (& diabetes) - more fat = less adiponectin
5. Potential antiatherogenic and anti-inflammatory properties - less adiponectin = more vessel disease

Question 2

Leptin?

Answer 2

1. Hormone released by adipocytes
2. Stimulates satiety
3. Crosses BBB by arcuate nucleus
4. Stimulates POMC / CART
5. Sends signal to anorexigenic centre in PVN

Question 3

Grhelin?

Answer 3

1. Hormone released by stomach
2. Stimulates hunger, gastric juices, GIT motility, prepares for food.
3. Crosses BBB at arcuate nucleus
4. Stimulates NPY / AgRP
5. That sends signal to orexigenic centre in LHA