Fat Digestion Flashcards
What are the classes of lipid (x5)
Fatty Acid Triacylglycerol Phospholipid Glycolipid Steroids
In what form is the majority of fat we injest
Triacylglycerol
Where does fat digestion take place
Small intestine
What enzyme is responsible for fat breakdown
Pancreatic Lipase
Are triacylglycerols water soluble?
No
They are water insoluble (hydrophobic)
Is lipase water soluble
Yes (hydrophilic)
What are the essential FA and how are they obtained
Linoleic Linoleic acid (derives Omega 3)
In plants, fish and seeds
What is the breakdown product after lipase
Monoacyl glycerol and 2x FA
What does bile do
Its an emulsifying agent that breaks down large fat droplets into multiple smaller ones
What is a micelle
Fat dropets are surrounded by bile salts. They have a hydrophobic centre and a hydrophilic surface
What happens after micelle formation
The lipase can breakdown the monoacylglycerol and FA into Glycerol and free FA
How does the acidic microclimate of the gut wall help with FA transport
??
What happens to the glycerol and FA when in the Enterocytes
They are reformed into Triaylglycerols in the smooth ER and processed in the golgi apparatus for exocytosis into the lymphatic system
What happens to the triacylglycerols before they can be exocytosed into lymph
They are packaged with APOB-48 into chylomicrons
What are the constituents of a chylomicron
Phospholipid (9%)
Cholesterol (3%)
ApoB (1%)
