Fast Zoonosis Flashcards
Causative microbe RMSF
rickettsia rickettsii
RMSF reservoir
Small woodland animals, domestic cats and dogs, deer
Fevers, malaise, calf myalgia, N/V, HA, arthralgia
Classic rash begins at wrist, forearm, and ankles, & spreads inward toward trunk
Palms and soles involved 80% cases
RMSF clinical findings
Hyponatremia, thrombocytopenia
Increased bilirubin and BUN
RMSF diagnostics
+
4X increase IgG antibody titer
RMSF Tx
doxycycline
chloramphenicol
Borrelia burdorferi
lyme disease
white footed mouse
lyme disease
flat-border, well-demarcated, blanching red oval patch) w/ fatigue, myalgia, fever, HA, hepatitis, pharyngitis
lyme disease
Bilateral Bell’s palsy 33% cases
AV blocks
Radiculopathy
lyme disease
Arthritis (knee MC)
lyme disease
diagnostics for lyme
clinical dx: erythema migrans in hx of tick exposure in endemic area) = treat empirically
lab diagnostics for lyme
ELISA to detect serum IgM and IgG antibodies; Western blot to confirm results
tularemia microbe
francisella tularansis
tularemia tx
streptomycin or gentamicin
meningitis: FQ/chloramphenicol
Flaviviridae
dengue
zika
west nile
japanese enchephalitis
filoviridae
Ebola
Acute febrile illness: retroorbital HA, malaise, severe myalgia/arthralgia, rash
dengue
Leukopenia, thrombocytopenia
Decreased albumin
Increased AST > ALT
dengue
+
Hemoconcentration hematocrit
3 phases of dengue
Febrile
Critical
Recovery
Polio-like flaccid paralysis
west nile
Fever, HA, fatigue, myalgia, arthralgia, /V, transient maculopapular rash, neuro sequelae
WNV
Neuro sequelae rare
western equine encephalitis virus
Children < 15 MC affected
Japanese encephalitis virus
vaccine
Japanese encephalitis virus
most severe mosquito-borne infection in US
Eastern equine encephalitis
Fever, HA, N/V
Encephalitis in 2%-6% cases
AMS to seizures and coma
eastern equine