Fast Track Flashcards
Triad of hyperviscosity syndrome (PV)
Bleeding, visual disturbances, focal neurologic deficits
Treatment for polycythemia vera
Low dose aspirin and phlebotomy to HCT of 45%
MCV elevated, RDW normal
Alcohol abuse, liver disease, hypothyroidism
MCV normal, Retic high, positive Coombs
Autoimmune disease
Detects antibodies on RBCs
Direct Coombs
Most common cause of aplastic crisis
Parvovirus B19 infection
Hema characteristic of aplastic crisis
Low Hgb
Few or no retic
Normal WBC & plt
Treatment for acute chest syndrome (sickle cell anemia)
Supportive (O2, hydration, analgesic)
Antibiotic (cephalosporin & macrolide)
Exchange transfusion
Classic pentad for TTP
CNS abnormalities, renal pathology, fever, microangiopathic HA, thrombocytopenia
Most common cause of HUS
Shiga toxin producing E. Coli O157:H7
Reversal agent for major bleeding after UFH use
Slow IV Protamine 1 mg per 100 units of total amount of IV UFH (max single dose 50mg)
Reversal agent for major bleeding after Enox use
Protamine 1 mg slow IV for every 1 mg of enox given in the prev 8h
Fibrinolytic agent & dose for ischemic stroke
Alteplase 0.9mg/kg with 10% of total dose given as IV bolus over 1 min; remainder as IV infusion over 60min
Most common location of malignant spinal cord compression due to mets
Thoracic vertebra
Malignancy most commonly associated with hypercalcemia
Breast, lung, multiple myeloma
