fast MRI and its applications Flashcards

1
Q

give some dis of fast mri

A

low SNR
low spatial resolution
short time for T1 recovery/t2 decay
increased costs e.g software

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2
Q

improvement in MRI speed due to:

phased array coils
new gradient tech (fast switching and stronger gradients)
faster sequenced

A
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3
Q

what are 3 main issues with short TR

A
  • tissues with long t1 dont fully recover
  • images become increasingly t1 weighted
  • compromises image quality
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4
Q

FLASH sequence is first sequence imaging technique to reduce flipping angle

  • optimal flip angle (for certain tissue) to receive largest signal (with short TR) given by ERNEST equation
A
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5
Q

there are 5 sequences used for fast MRI, what are they and state how each of them work

A
  • multi echo spin echo
  • multi slice spin echo
  • fast spin echo
  • echo planar imaging (gradient echo) / gradient echos in general
  • multishot spin echo / EPI (spin echo)
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6
Q

3 pros and negatives of using fast spin echo

A

pro:
short imaging time
allows breath-holding imaging
less susceptibility

cons:
lower SNR
HIGH SAR ( HEATING)
Longer ETL alters image contrast

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7
Q

2 main issues with EPI spin echo

A
  • can hardware de/rephase using FEG that fast
  • can software readout the signals that fast
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8
Q

whats the rough scan time for EPI

A

30-100MS/SLICE

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9
Q

EPI imaging are single shot sequences (1 RF), WHAT ARE 3 PROS OF EPI imaging

A
  • low SAR
  • signal losses associated with reduced TR eliminated
  • high sensitivity to susceptibility (important in fMRI)
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10
Q

NOTE: images from fast MRI look much better under homogenous magnetic field so shimming is very important

A
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11
Q

image matrix in k-space is hermitian, what does this mean

A

holds conjugate symmetry

  • top half of k-space contains info that errors bottom half same goes for left and right
  • can measure half and estimate the other (half-fourier)
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12
Q

what 3 negatives are associated with estimating k-space

A
  • reduced spatial resolution
  • low contrast
  • more artifacts
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13
Q

note: noise, in-homogeneities, patient effects etc introduce phase variations cross matrix making assumption of conjugate symmetry wrong

  • corrections are made by camping into 2nd half of matrix and assuming phase variation is linear
A
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14
Q

fractional NEX (number of excitations). Aqquire fraction of the k-space and assume the rest (as they are mirrored)

  • fractional echo shortens the minimum TE
A
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15
Q

3 pros for spiral imaging

A
  • more efficient k-space trajectory for fast MRI (tho not as fast as EPI)
  • better immunity to flow artefacts (no gradient at centre of k-space)
  • allows more room for magnetisation prep e.g diffuse weighting
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16
Q

what is parallel imaging

A

multiple receiver coils (phased array coils) to simultaneously get data, decreasing amount of k-space data needed, using coil sensitivity maps for reconstruction

17
Q

what are 2 forms of parallel imaging

A

SENSE - sensitivity encoding

GRAPPA - generalised auto calibrating partial parallel acquisition

18
Q

what is SENSE/how does it work

A

combines reduced Fourier encoding with coil sensitivity patterns to make artefact free image

  • applies knowledge of sensitivities of coil elements to calculate aliased signal component at each point
19
Q

what is mSENSE

A

modified SENSE

  • additional lines acquired at centre of k-space for each coil during scan
20
Q

what 2 aspects of scanner hardware are required for parallel imaging

A

phased array coils
gradients

21
Q

coil array in parallel imaging are used for both what?

A
  • signal reception
  • signal encoding
22
Q

coil array requirements:

  • multiple receiver channels, amplifiers, AD converters, computer memory, significant post processing to combine images
23
Q

phased array coils have many surface coils, give 2 pros and cons for this

A

adv- goos SNR, large FOV

con- multiple receiver channels costly, coil coupling

24
Q
  • the stronger/steeper the gradient, the faster the acquisition time

what is a slew rate

A

The slew rate (AKA “rise time”) is the speed at which the gradient reaches its maximum amplitude.

25
Q

Parallel imaging used for cardiovascular imaging (breath hold, real time) and brain (fMRI, single shot EPI diffusion)