Fast Hormonal Signal Transduction Processes (1) Flashcards
1
Q
Define signal transduction
A
Extracellular substances alter cell metabolism
2
Q
Define desensitisation
A
Transduction pathway no longer stimulated despite continued presence of hormone
3
Q
What are the two types of kinases/phosphatases?
A
Serine/threonine kinase
Tyrosine kinase
4
Q
Which protein domains bind to phosphorylated tyrosine residues?
A
SH2 and PTB
5
Q
Which protein domain binds to proline-rich areas?
A
SH3
6
Q
Which protein domain binds to inositol phosphate?
A
Pleckstrin homology
7
Q
Which protein domain binds to Ca2+?
A
EF hand domain
8
Q
Name a polypeptide hormone
A
Insulin
9
Q
Name an AA derivative hormone
A
Adrenaline
10
Q
Name an eicosanoid hormone
A
Prostaglandins
11
Q
Name a purine hormone
A
Adenosine
