Farmacological Tx For Cardiovascular Disease Flashcards
What’s the pharmacological group of candesartan?
Angiotensin II receptor antagonist
What’s the mechanism of action of candesartan?
Candesartan blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II by selectively blocking the binding of angiotensin II to the AT1 receptor in many tissues, such as vascular smooth muscle and the adrenal gland.
Common side effects of candesartan
Common side effects of candesartan include back pain, dizziness, and cold- or flu-like symptoms such as sore throat and nasal congestion.
What’s the pharmacological group of amlodipine?
Calcium channel blockers
What’s the amlodipine’s mechanism of action?
Inhibits the transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle
Which are the amlodipine’s side effects?
Swelling of the ankles or feet
Chest tightness
Dysnea
Dizziness
Arritmias
What’s the IACE’s mechanism of action?
Block the enzyme that converts angiotensin I into angiotensin II
Which are the IACE’s side effects?
Dry, nonproductive paroxysmal cough
What’s the AIIRA’s mechanism of action?
Blocking the angiotensin II receptors
Which are the AIIRA’s side effects?
Dizziness
Hyperkalemia
What’s the dihydropyridines pharmacological group?
Calcium channel blocker type L
What’s the dihydropyridine mechanism of action?
Binding and blocking voltage-gated L-type calcium channels found on smooth muscle cells of arterial blood vessels
Which are the dihydropyridine side effects?
Ankle swelling
Flushing
Palpitations
What’s the nondihydropyridine pharmacological group?
Calcium channel blockers
What’s the nondihydropyridine mechanism of action?
Blocking the calcium channels in te heart
