Farmacología colinergica Flashcards

1
Q

What is Pilocarpine primarily used for?

A

It is primarily used to treat glaucoma and dry mouth (xerostomia).

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2
Q

True or False: Cevimeline is a synthetic derivative of Pilocarpine.

A

True.

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3
Q

What is the mechanism of action of Pilocarpine?

A

Pilocarpine acts as a muscarinic agonist, stimulating the parasympathetic nervous system.

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4
Q

Fill in the blank: Cevimeline is primarily indicated for the treatment of ______.

A

dry mouth due to Sjögren’s syndrome.

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5
Q

What type of drug is Pilocarpine?

A

It is a cholinergic agent.

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6
Q

What is one of the major side effects of Pilocarpine?

A

Increased sweating (diaphoresis).

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7
Q

How is Cevimeline administered?

A

It is usually taken orally.

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8
Q

True or False: Pilocarpine can increase intraocular pressure.

A

False.

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9
Q

What is the distribution of Pilocarpine in the body?

A

Pilocarpine is widely distributed and can cross the blood-brain barrier.

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10
Q

Multiple Choice: Which of the following is NOT a side effect of Cevimeline? A) Nausea B) Diarrhea C) Increased urination D) Hair loss

A

D) Hair loss.

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11
Q

What is the primary clinical use of Pilocarpine in ophthalmology?

A

To lower intraocular pressure in patients with glaucoma.

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12
Q

Fill in the blank: The onset of action for Pilocarpine is ______ after administration.

A

30 minutes.

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13
Q

What is a common contraindication for using Pilocarpine?

A

Asthma or other respiratory conditions.

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14
Q

True or False: Cevimeline has a longer duration of action than Pilocarpine.

A

True.

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15
Q

What is the primary mechanism of action for Cevimeline?

A

It selectively stimulates muscarinic receptors in salivary glands.

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16
Q

Which condition is Cevimeline specifically used to treat?

A

Sjögren’s syndrome.

17
Q

What is one of the effects of Cevimeline on the body?

A

Increased salivation.

18
Q

Fill in the blank: Pilocarpine is often used in emergency situations to treat ______.

A

acute glaucoma.

19
Q

Multiple Choice: What is a common side effect of both Pilocarpine and Cevimeline? A) Dry mouth B) Blurred vision C) Excessive sweating D) Headache

A

C) Excessive sweating.

20
Q

What is the half-life of Cevimeline?

A

Approximately 5 hours.

21
Q

True or False: Both Pilocarpine and Cevimeline can cause gastrointestinal side effects.

22
Q

What is an important consideration when prescribing Pilocarpine?

A

Monitor for signs of cholinergic toxicity.

23
Q

Fill in the blank: The primary effect of Pilocarpine on the eye is ______.

A

miosis (pupil constriction).

24
Q

What should be monitored in patients taking Cevimeline?

A

Salivary gland function and signs of dehydration.

25
Multiple Choice: Pilocarpine is usually administered in which form? A) Injection B) Oral tablet C) Eye drops D) Patch
C) Eye drops.
26
What is a potential adverse effect of excessive dosing of Pilocarpine?
Severe hypotension.
27
Fill in the blank: Cevimeline is classified as a ______ agonist.
muscarinic.
28
What is the age limitation for using Cevimeline in children?
Safety and efficacy have not been established in pediatric patients.