Farmacología colinergica Flashcards
What is Pilocarpine primarily used for?
It is primarily used to treat glaucoma and dry mouth (xerostomia).
True or False: Cevimeline is a synthetic derivative of Pilocarpine.
True.
What is the mechanism of action of Pilocarpine?
Pilocarpine acts as a muscarinic agonist, stimulating the parasympathetic nervous system.
Fill in the blank: Cevimeline is primarily indicated for the treatment of ______.
dry mouth due to Sjögren’s syndrome.
What type of drug is Pilocarpine?
It is a cholinergic agent.
What is one of the major side effects of Pilocarpine?
Increased sweating (diaphoresis).
How is Cevimeline administered?
It is usually taken orally.
True or False: Pilocarpine can increase intraocular pressure.
False.
What is the distribution of Pilocarpine in the body?
Pilocarpine is widely distributed and can cross the blood-brain barrier.
Multiple Choice: Which of the following is NOT a side effect of Cevimeline? A) Nausea B) Diarrhea C) Increased urination D) Hair loss
D) Hair loss.
What is the primary clinical use of Pilocarpine in ophthalmology?
To lower intraocular pressure in patients with glaucoma.
Fill in the blank: The onset of action for Pilocarpine is ______ after administration.
30 minutes.
What is a common contraindication for using Pilocarpine?
Asthma or other respiratory conditions.
True or False: Cevimeline has a longer duration of action than Pilocarpine.
True.
What is the primary mechanism of action for Cevimeline?
It selectively stimulates muscarinic receptors in salivary glands.
Which condition is Cevimeline specifically used to treat?
Sjögren’s syndrome.
What is one of the effects of Cevimeline on the body?
Increased salivation.
Fill in the blank: Pilocarpine is often used in emergency situations to treat ______.
acute glaucoma.
Multiple Choice: What is a common side effect of both Pilocarpine and Cevimeline? A) Dry mouth B) Blurred vision C) Excessive sweating D) Headache
C) Excessive sweating.
What is the half-life of Cevimeline?
Approximately 5 hours.
True or False: Both Pilocarpine and Cevimeline can cause gastrointestinal side effects.
True.
What is an important consideration when prescribing Pilocarpine?
Monitor for signs of cholinergic toxicity.
Fill in the blank: The primary effect of Pilocarpine on the eye is ______.
miosis (pupil constriction).
What should be monitored in patients taking Cevimeline?
Salivary gland function and signs of dehydration.