FALLS & osteoporosis Flashcards

1
Q

Causes of FALLS

A

DAME

  1. Drugs (polypharmacy, alcohol).
  2. Age-related changes (gait, vision, balance, sarcopaenia, sensory impairment).
  3. Medical (stroke disease, CVS disease, Hypoglycemia).
  4. Environmental (obstacles, trailing wires, poor lighting)
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2
Q

Estimated Fragility Fracture Cost in the UK

A

£5 BILLION

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3
Q

History

A
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4
Q

Investigation of falls

A

BIB

dont forget B12 and thyroid

DEXA>osteoporosis

EEG if suspect seizure

CT> if head injury

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5
Q

Risk factors for falls

A
  • Lower limb muscle weakness
  • Vision problems
  • Balance/gait disturbances (diabetes, rheumatoid arthritis and parkinson’s disease etc)
  • Polypharmacy (4+ medications)
  • Incontinence
  • >65
  • Have a fear of falling
  • Depression
  • Postural hypotension
  • Arthritis in lower limbs
  • Psychoactive drugs
  • Cognitive impairment
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6
Q

Causes of SYNCOPE

A
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7
Q

Drugs causing falls

A
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8
Q

Who should receive a multifactorial risk assessment for falls? (3)

A

The following patients should receive a multifactorial risk assessment:

  1. 2 or more falls in the past YEAR
  2. Presentation for medical attention with a fall.
  3. did shit on the “Get Up & Go test” and/or the “Turn 180° test”
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9
Q

What should be covered in a mulitfactorial risk assessment and management plan?

A
  1. History of falls
  2. Consider the impact of co-morbidities
  3. Polypharmacy
  4. Osteoporosis risk
  5. Urinary incontinence.
  6. Perform a lying and standing BP
  7. Perform a “Get up and Go Test”
  8. home hazards–> OT
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10
Q

Examination

A

A functional assessment of their mobility – how do they mobilise, what with and what is their gait like

Vision–> snellen, visual acuity, fundoscopy

CVS examination – HR, ECG , lying and standing BP (at immediate, 3 and 5 minutes)

Neurological -

Musculoskeletal – assess their joints

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11
Q

what is a postitive postural BP test?

A

A drop in systolic BP of 20mmHg or more (with or without symptoms).
A drop to below 90mmHg on standing even if the drop is less than 20mmHg (with or without
symptoms).
A drop in diastolic BP of 10mmHg w/ symptoms (although clinically less significant than a
drop in systolic BP).

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12
Q

Tx postural hypotension

A

non-pharmacological

  • Withdraw offending medication
  • Rise slowly from supine to sitting to standing position
  • Avoid straining, coughing, and prolonged standing
  • Cross legs while standing
  • Raise head of bed 10 to 20 degrees
  • Small meals and coffee in the morning
  • Elastic waist high stocking
  • Increase salt and water intake
  • Exercise, eg, swimming, recumbent biking, and rowing

Pharmacological

1st line–>Fludrocortisone :expands BV and reduces salt loss.

Last line: Midodrine

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13
Q

How can you assess for mobility?

A

GAIT examination

  1. Timed “get up and go test”
  2. 180 degree turn test
  3. Gait speed
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14
Q

List 3 Fall Risk Assessment tools

A
  1. Falls Risk Assessment Tool (FRAT): helps u uncover any health issues that might make you more likely to fall, which you can discuss with your GP
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15
Q

Falls prevention & MDT (4)

A

MDT

  1. PT–> strength and balance training
  2. OT–>home hazards
  3. DR–>medication review (stopstart) co-morbidities, Bone health assessment (DXA scan)
  4. Psycology–> fear of falling leads to social isolation, reduce mobiltiy (CBT, refer to AgeUK for social support)
  5. Orthotics–> vision assessment and referral
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16
Q

what medications cause osteoporosis?

A
  • PPI
  • Steroids
  • Antiepileptics
  • SSRI
  • Aromatase inhibitors
  • Gonadotropin-releasing hormone agonists, such as goserelin.
17
Q

how do you perform a bone health assessment? (3)

what is the T score? (1)

A

1st —> FRAX tool estimates the 10-year risk of fragility fracture

2nd–> Offer a DEXA scan (dual-energy X-ray absorptiometry) to measure BMD (femoral neck and lumbar sacral)

Bloods: vitamin D, Ca+, TFT, PTH

  • TSH inhibits bopne resorption (hypo or hyper)
  • anybody who falls from nonstanding postition is a “fragility fracure”
  • Bone density can be represented as a Z score or T score
  • T score: based on bone mass of YOUNG reference population
18
Q

What is the cut off T-score for osteoporosis?

A

A T-score of -2.5 and below confirms osteoporosis and is diagnostic.

if T score is -1 to -2.5 they have osteopenia

19
Q

Management of Osteoporosis

A

Conservative: Lose weight, healthy lifestyle/Diet, stop smoking, reduce falls, reduce alchohol

Calcium and VitD (colecalciferol)

Medical

1st line–> Bisphosphonates (reduces osteoclast activity, preventing the reabsorption of bone)

  • Alendronate 70mg once weekly (oral)
  • Risedronate 35 mg once weekly (oral)
  • Zolendronic acid 5 mg once yearly (intravenous)

2nd line–>

Denoxumab (blocks activity of osteoclasts)

Strontium ranelate is a similar element to calcium that stimulates osteoblasts and blocks osteoclasts but increases the risk of DVT, PE and myocardial infarction.

Raloxifene is used as secondary prevention only. It is a SERM it stimulates oestrogen receptors on bone but blocks them in the breasts and uterus.

HRT considered in women who have early menopause

20
Q

instructions on taking Bisphosphinates? SE? (4)

A
  • Oral bisphosphonates are taken on an empty stomach sitting upright for 30 minutes before moving or eating to prevent Reflux and oesophageal erosions.
  • Atypical fractures (e.g. atypical femoral fractures)
  • Osteonecrosis of the jaw
  • Osteonecrosis of the external auditory canal
21
Q

Follow up for Osteoporosis

A

Low risk patients not on Tx: should be given lifestyle advice and followed up within 5 years for a repeat assessment.

Patients on bisphosphonates: should have a repeat FRAX and DEXA scan after 3-5 years and a treatment holiday should be considered if their BMD has improved and they have not suffered any fragility fractures. This involves a break from treatment of 18 months to 3 years before repeating the assessment.

22
Q

Primary hyperparathyroidism causes bone loss in the distal fore arms, so we dexa scan the distal for arm in this case ok?

A
23
Q

Dangers of a long lie

A
  • pressure ulcers
  • incontinence
  • AKI
  • incr risk mortality