fall final Flashcards
what is the fluid mosaic model?
the structure of the cell membrane
what are the 6 functions of proteins?
-maintain cell shape
-coordinate changes inside and outside the cell
-receptors for chemical messengers from other cells ;
-enzymes that catalyze reactions;
-glycoproteins are involved in cellular recognition
-the transport of substances across the membrane.
what is a selectively permeable cell?
cell mem that allows some substances to cross
more easily than others
what is diffusion?
passive transport, requires no energy, the movement of
a substance down its concentration gradient from an area of higher concentration to an area of lower concentration
what is facilitated diffusion?
passive transport of a
substance across a membrane through a specific transport protein, down its concentration gradient.
What is aquaporin?
a pore forming prtein that allows for fast diffusion
what is osmosis?
the movement of water across a sleetivly permeable mem until equalibrium
what is hypertonic?
a higher concentration outside of the cell relative to the inside of the cell (crenates, loss of water)
what is hypotonic?
lower concentration outside of the cell, relative to the inside of the cell (bloating)
what is isotonic?
the same concentration
inside and outside of the cell
Define osmoregulation
describes how cells
control this water balance to maintain homeostasis
What is active transport? where does it get its energy from? What is actually transferred to the transport protein to give it energy?
substances move against CG and require energy.
ATP supplies energy
the phospahte group in ATP is transfered to get energy
In active transport do substances move up or down their concentration gradient?
move aginst CG from low CG to high CG
what is endocytosis?
get things from the outside of the cell to the inside
plasma membrane forms a vesicle surrounding
substances on the outside of the cell and this forms a vesicle within the cell
what are the three kinds of endocytosis?
-phagocytosis; cell eating, pseudopodia creates vacuole to be digested by a lysosoome
-pintocytosis; cell drinking, not specific, create small vesicles to get fluid from extracellular matrix that is brought into cell and does not get dissolved.
-receptor mediated; very selective, coated in proteins that
specifically bind particular molecules from their surroundings, these are pinched off to form vesicles within the cytoplasm.
what are the 2 basic forms of energy?
kinetic and potenial energy.
kinetic- the energy of motion like riding a bike, heat and light as well
potential- energy that matter possesses as a result of its location or structure, energy waiting to be used, like water held back behind a dam
what is Thermodynamics?
The First Law of Thermodynamics states:
The Second Law of Thermodynamics states:
the study of energy transformations.
1- law of energy conservation, Energy can be transferred and transformed, but it cannot be created or destroyed
2- the entropy law, all things tend towards max randomness
what is the primary difference between exergonic and endergonic reactions?
exergonic- reactants contain more energy than the products and the reaction releases
energy to the environment
endergonic- create products that are higher in energy, from reactants that are lower in energy
If the energy of the products is less than the energy of the reactants, the reaction must be..
exergonic
If the energy of the products is more than the energy of the reactants, the reaction must be..
endergonic
What is metabolism?
all exergonic and endergonic reactions in the body
what is energy coupling?
he use of energy released from exergonic reactions to drive essential endergonic reactions.
What is ADP and ATP?
ATP- cell energy, made of adenine, ribose, and 3 phosphate groups
ADP- what ATP becomes after energy is released (loss of a P group)
What is phosphorylation
he transfer of a phosphate group to another molecule. This
energizes the molecule so it can be used later in cellular work.
What is the energy barrier of a chemical reaction called and what do enzymes do to this barrier?
- activation energy, the amount of energy that reactants must absorb before a chemical reaction will start
What is an active site on an enzyme? What would happen to the active site if the protein became denatured?
-The part of an enzyme where a substrate binds by groove
-stop functioning
What is a cofactor? what is a coenzyme?
- non protein molecule required for functioning of enzymes (binds to active site) like iron
- a cofactor that is organic molecule like folic acid
what is tonicity
the ability of a solution surrounding a cell to cause that cell to lose or gain water
what is exocytosis?
exporting large substances out of cell
what are competitive inhibitors?
the inhibitor binds to the active site and competes w substrate for the active site and slows rate of reaction
what are noncompetitive inhibitors?
binds to the enzyme at another location, referred to as an allosteric site so it changes the shape of the enzyme so that the
active site no longer fits the substrate
what is a proenzyme?
enzymes in the body are produced in an inactive form that eventually will be active.
protects cell from digesting itself
what is feedback inhabition?
a method of metabolic control in which the product of a metabolic pathway acts as an inhibitor of an enzyme within the pathway and shuts off its production when enough is made.
what is cellular respiration?
exergonic, a series of chemical reactions that break down glucose to produce ATP
when is a substrate oxidized?
when a substrate LOSES an electron and increases oxygen (lose H)
when is a substrate reduced?
when it GAINS electrons and H
what is a redox reaction?
a chem reaction that involves the transfer of electrons
What is NAD and what is its primary function in cellular respiration?
nicotinamide adenine dinucleotide is a
coenzyme made from vit niacin, used as an electron shuttle, accepting electrons in redox reactions and becoming reduced to NADH + H+
what is FAD?
Flavin adenine dinucleotide is another electron acceptor, becomes reduced to FADH2, so also carries/transfers 2 electrons
what is the final electron acceptor in cellular respiration?
oxygen
what are the steps in order of cell resp?
Glycolysis, pyruvate oxidation, the Citric Acid Cycle, and
Oxidative Phosphorylation
what is glycolysis?
occurs in cytoplasm and doesnt require oxygen
6 glucose is broken down to ATP
adds 2 phosphate to 6 glucose on both ends
splits glucose in half called GP3
END PRODUCTION- 2 pyruvate, 2 ATP, 2 NADH, 2 H
what is citric acid cycle?
happens in mito matrix
2 carbons enter and make citrate
NAD reduced to NADH which releases Co2
END PRODUCT- 4 Co2, 2 ATP, 6NADH, 6H, 2 FADH
what is pyuvate oxidation?
happens in mitochandrial matrix
the pyruvate formed at the end of glycolysis enters the mitochondrion and is oxidized to become Acetyl Co-enzyme A (Acetyl CoA)
END PRODUCTS- acetyl CoA - 2Co2, 2 NADH, 2 H
what is total chem outcome of cell resp? how many total electrons?
4 ATP + 10 NADH + 10 H + 2 FADH
24 electrons total
During the Citric Acid Cycle, how many NAD+ and FAD are reduced and how many ATP are made per Acetyl CoA/ glucose?
6 NADH and 2 FADH2
2 ATP
Does the citric acid cycle consume oxygen?
no
what is oxidative phosphorylation? what are the 3 proteins?
elec transport
in mito matrix
1- gets elecs from NADH and pumps them across mem against CG
3 and 4
Hydrogen ions fall down their concentration gradient through a particular enzyme that is used add a phosphate group to ADP to make ATP, what is the name of the name of this enzyme?
ATP synthase, thru process called chemiosis phosphoralyzes ADP to ATP and can generate up to 28 ATP
How many ATP can be produced every second in a working muscle cell
10 million ATP
what would happen without oxygen in cell resp?
This whole system would back up and the production of the majority of your ATP would stop – this would starve your cells of energy
How does NADH + H+ get oxidized back to NAD if there is no oxygen?
lactic acid fermentation, pyruvate is reduced to lactate (lactic acid) and can make ATP
and ethanol/Alcohol fermentation, yeasts use this as they convert pyruvate to CO2 and
ethanol to oxidize NADH
what are faculative anaerobes?
yeast, They make ATP either by fermentation or oxidative phosphorylation,
depending on whether oxygen is available or not…but will always use oxidative phosphorylation if
given the option as it releases far more ATP
what are obligat aneieorobes?
oxygen is toxic to them and they need 16x more glucose to survive
In photosynthesis carbon dioxide becomes ______ to glucose and water becomes _______ to oxygen
what about in respiration?
reduced
oxidized
glucose is oxidized to carbon dioxide and oxygen is reduced to water