Facts Flashcards
Hormone produced by yolk sac tumors
AFP
Hormone produced by choriocarcinoma
hCG
Hormone produced by embryonal carcinoma
AFP and hCG
Teratoma
AFP and hCG in 50%
Seminoma description
Ages 30-35, >65. Most common, radiosensitive, NO hemorrhage or necrosis.
Embryonal carcinoma description
Ages 20-25. Bulky, hemorrhage and necrosis present. Increased AFP and hCG
Yolk sac (endodermal sinus) tumor description
Most common in children < 5. Schiller-Duval bodies, glomeruloid bodies. AFP produced
Choriocarcinoma description
Ages 20-30. Most aggressive, painful. hCG produced. Commonly mixed with other tumor types. Contains syncytiotrophoblasts and cytotrophoblasts. May cause gynecomastia bc hCG is LH analog.
Teratoma
All ages. Produces AFP and hCG in 50% of cases.
Malignant lymphoma.
Most common testicular cancer >60 years old. Diffuse large cell lymphoma involves both testes. Poor prognosis.
Hydrocele description
Most common cause of testicular enlargement, positive transillumination test, ALWAYS associated with indirect inguinal hernia. Failure to close of tunica vaginalis. Fluid accumulates between layers of tunica vaginalis.
Epididymitis under 35 yo
Gonorrhea, chlamydia
Epididymitis over 35 yo
E. Coli, pseudomonas aeruginosa
Bowen’s disease of penis
Leukoplakia involving shaft of penis and scrotum, HPV type 16 association, erythroplasia of Queyrat on glans and prepuce.
Leydig Cell Tumor
Adult men, may produce androgens and/or estrogens, can cause gynecomastia or feminization. Histologically benign, most are small.