Factors contributing to breathlessness and it's management Flashcards
Define breathlessness.
Awareness of increased effort which is unpleasant and recognised as inappropriate.
Define Orthopnoea.
Breathlessness upon lying down.
Define Paroxysmal nocturnal dyspnoea (PND)?
Occurs after 1-2 hours of being supine ( Increased VR puts excess load on the right side of the heart).
What does the term breathlessness mismatch refer to?
breathlessness mismatch due to a mismatch between demand for ventilation and afferent information about actual ventilation.
Reminder
see LC at 14:00 for understanding about eh load-capacity relationship = a model for understanding breathlessness.
What is the aetiology of breathlessness?
- Increased respiratory drive
- increased load
- impaired capacity
What things can increase your reparatory drive?
- Hypercapnia/acidosis
Poor relationship between elevated CO₂ and dyspnoea but strong correlation between hypercapnia and resulting in increased VE. - Hypoxia
(Caused by; anaemia, high altitude, V(=ventilation)/Q(=perfusion) mismatch)
poor correlation between hypoxia and breathlessness but strong correlation between hypoxia resulting increase in Ve.
What can increase the load on the respiratory muscle pump?
- Reduced compliance of the lungs
- Obesity
- Airflow obstruction
What can impair the capacity of the respiratory muscle pump?
- Respiratory muscle impairment;
- force-length relationship
- force-velocity relationship (respiratory muscles, velocity is measured as flow)
*Peripheral muscle impairment (occurs when you avoid activity and have deconditioned, you produce more lactic acid and have to breath more for a given activity)
also hyperinflation
reminder
see LC at 21:00 for the breathing, thinking, functional clinical model.
During assessment of breathlessness what sensations would you measure?
- Intensity
- Unpleasantness
- Sensory aspect
How could you assess the function/ impact of breathlessness?
- Modified MRC scale
- BORG scale
- Chronic respiratory questionnaire (CRQ)
- St George’s respiratory questionnaire.
What are some general aims of management of breathlessness?
- Reduce ventilatory demand;
Reduce metabolic load.
Reduce central drive. - Reduce load (ventilatory independence).
- Increase capacity.
- Alter central perception.
How can you reduce metabolic load?
- Exercise training = reduction in lactate for a given activity.
- Supplement O₂
(Very little support evidence though, mainly thought to be related to reduction in ventilation) only to be used in hypoxaemia.
How can you reduce their central drive for management of breathlessness?
- Oxygen therapy:
Reduced hypoxic drive from chemoreceptors proportional to reduction in ventilation. (remember the supporting evidence for this is poor) - Pharma logical therapy; e.g. Opiates
(reduce Ve at rest and during exercise - alter central processing of neural signals within CNS to reduce sensations associated with breathing).
(supporting evidence also poor with variable results).