Factors affecting clearance Flashcards
1
Q
Production of the hormone
A
The more hormones are produced and released in the blood, the harder
it is to clear
2
Q
Half-life of
the Hormone
A
More significant
Amount it takes for a hormone, or any substance, to decrease its concentration by 50%
Once the hormones are free in the blood (not bound to any proteins), they are more subjected to excretory processes in the kidneys and liver
3
Q
Clearance Mechanism
A
Degradation by end target organ
Tissue binding
Liver and Kidneys via excretion