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Micro > FA Psychiatry > Flashcards

FA Psychiatry Flashcards

1
Q

Signs of physical abuse

A 
Spiral fractures*
Burns
Subdural hematomas
Patterned marks and bruising
Rib fractures
Retinal hemorrhage or detachment
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2
Q

Neuro findings in ADHD

A

Decreased frontal lobe volume/metabolism

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3
Q

NT change: Alzheimer

A

Decreased ACh

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4
Q

NT change: Depression

A

Decreased NE, 5HT and DA

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5
Q

NT change: HD

A

Decreased GABA
Decreased ACh
Increased DA

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6
Q

NT change: PD

A

Decreased DA
Increased 5-HT
Increased ACh

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7
Q

NT change: Schizophrenia

A

Increased DA

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8
Q

NT change: Anxiety

A

Increased NE

Decreased 5HT and GABA

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9
Q

Destroyed in Korsakoff amnesia?

A

Mamillary bodies

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10
Q

What diagnostic test will be abnormal in delirium?

A

EEG (vs. normal in dementia)

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11
Q

Formication is seen in…?

A

Cocaine use and OH withdrawal

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12
Q

Decreased dendritic branching is seen with what disorder?

A

Schizophrenia

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13
Q

Sleep changes in depression

A 
EMA
Decreased slow-wave sleep
Decreased REM latency
Increased REM early in sleep 
Increased total REM
Repeated nighttime awakenings
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14
Q

Postpartum blues timeline

A

Starts 2-3 days after delivery
Resolves within ten days
(seen in 50-85%)

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15
Q

Postpartum depression timeline

A

Starts within 4 weeks of delivery

Lasts 2 weeks to a year or more

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16
Q

What are the ABC cluster personality traits?

A

A = awkward
Paranoid
Schizoid
Schizotypal

B = B movies (dramatic)
Histrionic
Borderline
Antisocial
Narcissistic

C = Cowardly
Avoidant
Obsessive-compulsive
Dependent

17
Q

Cause of narcolepsy

A

Decreased orexin production in lateral hypothalamus

18
Q

Treatment of narcolepsy

A 
Daytime stimulants (amphetamines, modafinil)
Nigh-time sodium oxybate (GHB)
19
Q

Treatment of restless leg syndrome?

A

DA agonists (pramipexole)

20
Q

Mechanisms of antipsychotics

A

Block D2 and increased cAMP

21
Q

Evolution of EPS symptoms (4’s)

A

4 hours acute dystonia
4 days akathisia
4 weeks parkinsonism
4 years TD

22
Q

Treatment NMS

A

Bromocriptine (DA agonist) or dantrolene

23
Q

High potency typical antipsychotics

A

Trifluoperazine
Fluphenazine
Haloperidol
*EPS symptoms

24
Q

Low potency typical antipsychotics

A

Chlorpromazine
Thioridazine
*anticholinergic, antihistamine and alpha1 blockade

25
Q

Chlorpromazine vs. thioridazine eye effects

A

Chlorpromazine - corneal deposits

Thioridazine - retinal deposits

26
Q

Clozapine SE

A

WG
Seizures
Agranulocytosis
Wet pillow syndrome

27
Q

Buspirone MOA

A

5HT1a (partial agonist)

28
Q

Lithium toxicity effects

A 
Tremor
Sedation
Edema
Heart block
Hypothyroidism
Polyuria (ADH antagonist)
29
Q

Mirtazapine: MOA, effects (aside from decreasing depression)

A

alpha 2 antagonist (increased release of NE and 5HT)
Potent 5HT2/3 antagonism
Sedation and increased app/WG

30
Q

Trazadone: MOA and SE

A 
Blocks 5HT2 (autoreceptor) and alpha1 adrenergic receptors
SE: priapism, sedation and postural hypotension
31
Q

Treatment of serotonin syndrome

A

cyproheptadine

32
Q

SNRIs and indications/SE

A

Venlafaxine - GAD and panic disorder
Duloxetine - diabetic neuropathy

SE - increased BP

33
Q

SSRIs

A

Citalopram
Sertraline
Fluoxetine
Paroxetine

34
Q

MAOIs

A

Tranyylcypromine
Phenelzine
Isocarboxazid
Selegiline

35
Q

TCAs

A 
Amitriptyline
Nortriptyline
Imipramine
Desipramine
Clomipramine
Doxepin
Amoxapine
36
Q

TCA MOA

A

Block reuptake of 5HT and NE

37
Q

Amitriptyline (tertiary) vs. nortriptyline (secondary) - which has more anticholinergic effects

A

Amitrptyline

38
Q

Treatment of TCA toxicity (cardio)

A

NaHCO3

Micro (5 decks)

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