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BMS2021 F > F4 > Flashcards

F4 Flashcards

1
Q

For which cancers can oncogenes be associated with chromosomal translocations:

A

CML - chronic myeloid leukemia
B cell lymphoma

Oncogenes activated due to chromosomal translocations

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2
Q

what is promyelocytic leukemia ?

A

rearrangement of the gene for RAR (nuclear transcriptional regulator)
makes it insentitive to retinoic acid which is essential for HSC differentiation

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BMS2021 F (4 decks)

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