F-med Flashcards
The drug of R.I.P.E Tuberculosis tx that can cause Paresthesias in fingers/toes
Isoniazid
RIPE regimen
Rifampin
Isoniazid
Pyrazin
Ethambutol
SE of Ethambutol
Optic Neuritis
If taking Ethambutol, should have regular eye checkups
Peripheral neuropath SE a/w Isoniazid are dose dependent, pts taking this should co-administer _______ to help
Vit B6- Pyridoxine
After two months of RIPE tx, what meds do you KEEP TAKING?
Rifampin and Isoniazid- the first two out of the regimen
ctd for the entire 6 mo
Pott’s dz
TB of the vertebrae, manifesting as:
Osteomyelitis and Arthritis
Vit D deficiency
Rickets (kids)
Osteomalacia
Tetany
Night vision loss, dry skin, growth delay, Bitot spots on conjunctiva of eye are a/w deficiency of WHAT vitamin?
Vit A
Vit B6
Pyridoxine
Vit B12
Cobalamin
Vit B2
Riboflavin
Vit B1
Thiamine
Vit B3
Niacin
Pts w Cholestatic Jaundice have
decreased total bile salt pool size
GGT level
gamma-glutamyl transferase, enzyme mostly found in liver. when liver is damaged, leaks out into blood
Signs of Cholestasis
Elevated:
Bilirubin
Alk phos
GGT
Charcot’s triad
RUQ pain
Fever
Jaundice
Which type of PUD ulcer is more common
Duodenal ulcer
Triple drug therapy for H. Pylori
Amoxicillin
Clarithromycin
PPI- Omeprazole
Dosing of H. Pylori tx
Amoxi 1000 mg
Clarithro 500 mg
Omeprazole 20 mg
everything BID x14d
When to do test of cure for H. Pylori?
at least 4 weeks after pt has completed therapy
What do you need to monitor if pt is on Allopurinol therapy?
It’s excreted by kidneys
Measure KIDNEY FX, with Cr levels
Kidney fx test
Cr
How often to measure Creatine level w pt on Allopurinol?
every 2-4 weeks
1st line PROPHylaxis for Gout
Allopurinol
Ideal Uric Acid level in someone with Gout
< 6 mg/dL
Needle shaped crystals with NEG birefringence
Gout
Tx of Acute Gout
NSAIDs
Steroids
Colchicine
What things can trigger/ make worse Gout?
Loop diuretics
Thiazide diuretics
Recommendations for long term f/u of pts with Hodkin’s lymphoma who have been treated to remission
Annual Mammogram at age 40, OR
5-7 yrs after Radiation
Clinical sx of Hodkin Lymphoma
Painless cervical swollen lymph nodes Itching Fever Night sweats Weight loss (b sx) Frequent infections
Cells pathognomic for Hodkins lymph
Reed- Sternberg
Reed Sternberg cell looks like
“Owl’s eye”
Hodkins lymph
Mediastinal mass on CXR
Hodkins lymph!!
Also Hepatosplenomegaly, B sx- night sweats, weight loss, fever
After person has received tx (chemo or radiation) for Hodgkin lymph, what secondary CA is likely to develop?
Lung
Breast
GI
Reed Sternberg
Hodkin Lymph
Tx of Acne vulgaris
Mild-mod: Topical retinoids or abx + peroxide
Mod: add oral Abx
Severe: Isotretinoin “Accutane”
Criteria for Hypotension
<90 sys
<60 diast
Most common location for Esophageal foreign body
Level of Cricopharyngeus muscle- C6
Antibodies specific for SLE (Lupus)
Anti-dsDNA
Anti-Smith
Other sx that can be a/w Lupus
Fever Low wbc Thrombocytopenia Hemolysis Delirium, Psychosis Alopecia Oral ulcers Pericarditis Pleural or Pericardial effusion Arthralgia Proteinuria
Most common way that Lupus can affect your lungs
Pleuritis- inflammation of the pleura- the lining that covers the outside of the lungs
Tx of Lupus
Hydroxychloroquine
Steroids
Immunosuppressant
NSAIDs
Drug inducing lupus
HIPPS
Hydralazine Isoniazid Phenytoin Procainamide Sulfa
Stages of Lyme Disease (Borr Burgdorf)
I: Erythema migrans “bullseye”, fever, fatigue, myalgia, HA
II: Myocarditis, Bells palsy
III: Chronic arthritis, chronic encephalopathy
Tx of Lyme dz
Doxy
Pregnant: Amoxicillin
What is diff about the Bell Palsy a/w Lyme disease?
It’s BILATERAL!
pathognomic for Lyme dz
Avoid this type of DM drug if family or personal hx of THYROID cancer
GLP-1 RA, “tides”
Victoza, Saxenda, Trulicity
Most common cause of Cushings syndrome
Excess steroid use
exogenous
Most common ENDOGENOUS cause of Cushings syndrome is
Cushings dz- excessive secreation of ACTH by pituitary tumor
most commonly a Benign Pituitary Tumor