F&E Flashcards
Osmolality
Osmolality are particles in a given weight of fluid
Osmolarity
are particles in a given volume of fluid
A serum osmolarity, Normal range, too high, too low?
is a method of determining if someone is overhydrated or dehydrated
- Normal range is roughly 280 to 300
- Too high indicates dehydration
- Too low indicates fluid overload
- For our purposes they will be interchangeable
Intracellular
is the fluid inside the cell
-2/3 of fluid volume
Primary electrolytes
Potassium
Phosphate
Sulfate
Extracellular
is the fluid outside the cell
1/3 of fluid volume
Primary electrolytes
Sodium
Chloride
Bicarbonate
What is the fluid called that is inside the blood vessels?
intravascular
What is the fluid called in-between the cells?
interstitial
What three components determine the fluid balance in these compartments?
- Protein– keeps fluid invascualr space (colloid oncontic pressure)
- Blood vessel integrity – keeps fluid in vascular space
- Hydrostatic pressure- pushes fluid into interstitial space
Osmotic Pressure is impacted by what?
Osmolality- Pressure exerted to prevent movement of water out of the intravascular space
Colloid Oncotic pressure- Proteins attract water and hold onto water
Hydrostatic Pressure
Arterial blood pressure (higher)
Venous pressure (lower)
Rate of blood flow
Filtration Pressure
-Process that transfers nutrients and oxygen to cells
Hydrostatic minus osmotic
-At the arterial end of the capillary the fluid is pushed into tissues
-At the venous end the fluid is brought back into circulation
Tonicity
Concentration of fluid
Isotonic
Equal concentration of water and electrolytes
Hypertonic
- Concentration of electrolytes outside cell is higher
- Concentration of water outside cell is lower
Hypertonic solution : cause cells to shrink
Hypotonic
- Concentration of electrolyte outside cell is lower
- Concentration of water outside cell is higher
Hypotonic solution cause cells to swell
Hypotonic Solutions (<250 mOsm/ L)
- 0.45% sodium chloride also known as “half normal saline”
- Used for: hypernatremia and diabetic ketoacidosis. Due to tonicity can cause hypotension
Isotonic (250 – 375 mOsm / L)
- 0.9% sodium chloride also known as “normal saline”
- Most common fluid used for hydration. Only solution used with blood product administration
- Lactated Ringers
- Used with surgery, trauma, burns. Not recommended for patients with renal problems
Hypertonic (> 375 mOsm/L)
-3% sodium chloride
Used in emergency situations for cerebral edema
Dextrose 5% in 0.45% sodium chloride or called “D5 ½ normal saline”
-used for hypovolemia with hypernatremia
D5 normal saline- used with electrolyte and fluid loss
Crystalloids
-Aqueous solution with electrolytes
Hypotonic, isotonic, and hypertonic solutions (chart from last slide)
Colloids
-Contain large molecules that do not transport outside of the intravascular space
Also called “volume expanders”
Blood products
A fluid type only administer normal saline with blood!
Functions of Colloids
- Function to increase the osmotic pressure in the intravascular space leading to fluid being pulled into the intravascular space
- Albumin, Dextran, Hetastarch
Nursing consideration of colloids
-Must be administered carefully or can cause signs of fluid volume excess (listed out on the fluid volume excess slide)
Packed RBCs
Used for blood loss
- 1 unit roughly increases hemoglobin by 1 g/dL
- Usually reserved for a hemoglobin less than 7 or 8 g/dL
Platelets
Given when there is a reduced level of platelets
Fresh, Frozen, Plasma
-Used for trauma, burns, shock, or bleeding and clotting disorders
Cryoprecipitate
Used for clients with hereditary disorders that lead to inadequate clotting
Nursing Considerations for Blood products
-Should consent be obtained before administering blood products
-Blood type and Rh factor protein are determined to match a person with the right type of donor
Type and crossmatch performed
-A consent must be obtained before administration of any blood products
Universal Donor
O neg
Universal Recipient
AB positive
Signs for Transfusion reaction
- Fever, chills
- Altered blood pressure
- Respiratory difficulty
- Signs of an allergic reaction
Dehydration
Loss of body water but electrolytes remain consistent
Fluid Volume Deficit
- Loss of both fluid and electrolytes.
- Can also include a loss of circulating blood volume and perfusion to tissues
- Hypovolemia
Fluid volume excess
-Electrolytes are same or altered
Edema
-Can relate to both deficit and excess
Dehydration Causes
- Inadequate water intake
- Increased GI losses
- Fever
- SSRIs and Benzo decrease thrist mechanism
- DKA