Eyes In Systemic Disease

Question 1

Myotonic dystrophy eye S&Ss

Answer 1

• Early onset cataract
  
  • stellate posterior cortical cataract (pathogonomic)
  • or ‘Christmas tree’ polychromatic cataract
• Ptosis
• Hypermetrophia

Question 2

NF type 1 eye S&Ss

Answer 2

• Optic glioma
• Lisch nodules (pathogonomic)

Question 3

Thyroid eye disease S&Ss

Answer 3

• Grittiness, photophobia, lacrimation
• Hyperaemia, chemosis, periorbital swelling
• Lid retraction, proptosis
• Optic neuropathy, restrictive myopathy, diplopia

Question 4

Thyroid eye disease treatment

Question 5

Thyroid eye disease pathophysiology

Question 6

Dermatomyositis eye S&Ss

Answer 6

• Heliotrope rash on eyelids
• Systemic autoimmune disease - dry eyes, scleritis etc.

Question 7

Marfan’s syndrome S&Ss

Answer 7

• Disocated lens (ectopia lentis)
  
  • usually superotemporal dislocation
  • zonules intact

Question 8

RA eye S&Ss

Answer 8

• peripheral ulcerative keratitis
• scleromalacia perforans (pathognomonic)
• scleritis

Question 9

Sjogren’s syndrome eye S&Ss

Answer 9

• gritty, dry eyes

Question 10

‘Mutton-fat’ keratic precipitates - granulomatous anterior uveitis aetiology/ underlying conditions

Answer 10

• Sarcoidosis
• TB
• Syphilis

Question 11

Posterior synechia (iris adhesions to the anterior lens capsule) aetiology

Answer 11

• HLA B27 anterior uveitis (ankylosing spondylosis)
• Idiopathic anterior uveitis

Question 12

Posterior uveitis 3 aetiology

Answer 12

• Retinitis
• Vasculitis
• Optic neuritis

Question 13

Uveitis subtypes

Answer 13

• Anterior uveitis (iris)
• Intermediate uveitis (ciliary body)
• Posterior uveitis (choroid)