Eye patho 1 Flashcards

Blindeness of the inner eye

1
Q

Chalazion patho

A

An acute or chronic inflammation of the eye lid secondary to blockage of one of the Meibomian or Zeis glands in the tarsal plate.

This blockage causes the stagnation of sebaceous which leads to the formation of a lesion.

Most lesions will point in the direction of the conjunctival surface causing redness and swelling.

More common in people with Blepharitis, Acne Rosacea, and Seborrheic Dermatitis.

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2
Q

Chalazion clinical presentation

A

Usually presents with a painless lump that develops in the lid or the lid margin, occasionally with mild erythema.
Presents very similar to a Hordeolum and may be difficult to differentiate between the two.

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3
Q

Chalazion management

A

Warm compress several times/day followed by massaging eyelid towards lid margin
Refer to an MO or SMA for referral to ophthalmologist if not resolved in a few days.

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4
Q

Hordulem stye patho

A

A Stye refers to an external hordeolum. It is an acute bacterial (usually Staph) infection of the follicle of an eyelash and adjacent sebaceous glands (Zeis) or sweat glands (Moll). It is commonly located at the eyelash line and has the appearance of a small pustule.

An internal hordeolum affects the meibomiam glands associated with eyelashes. The definitive difference is that it is located to the inner surface of the tarsal plate.

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5
Q

Hordulum clinical presentation

A

Other signs and symptoms besides the pustule include pain, edema, and erythema of the eyelid

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6
Q

Hordulum management

A

IAW ref (C51) warm compress with erythromycin ophthalmic ointment twice daily for 7 to 10 days.
Also Ref to Restricted acts Pharmaceuticals: table 2.
Systemic antibiotics may be required for significant surrounding cellulitis.
Refer to an MO or SMA for referral to ophthalmologist.

Learning support

Ensure to always educate your patients on infections and there implications if not treated appropriately.
Do not be shy to also educate patients on proper hand washing techniques as well as informing them to refrain from picking or attempting to ‘pop’ the pustule, this may cause further complications.

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7
Q

Conjuctivitis def

A

An inflammatory condition of the conjunctiva and is a common cause of the “red eye”.

There are many different causes but what are the 3 main causes?

Allergic, viral, bacterial

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8
Q

Allergic conjuctivitis

A

The allergen causes cross-linkage of membrane-bound IgE that causes mast cells to degranulate.

This causes a release and cascade of allergic and inflammatory mediators, such as histamine.

The most common allergen in nature to cause ocular symptoms is grass pollen.

Immunoglobulin E (Antibody)  Causes Allergic Reaction
Mast Cell – A cell filled with Basophil Granules (Releases histamine during inflammatory or allergic response)
Basophil – Type of White Blood Cell

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9
Q

Allergic conjuctivitis symptoms

A

Common signs and symptoms include: watery discharge, redness, and itching.
Red and swollen eyelids.
Injected and swollen conjunctiva with papillae on the inferior conjunctival fornix .

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10
Q

Allergic conjuctivitis management

A

Remove known allergen.

Cool compress 4 times/day.

Artificial tears, topical or systemic antihistamines.

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11
Q

Viral conjuctivits patho

A

Most common cause is adenovirus however can appear as part of systemic viral infections like Mumps, Measles, and Influenza.

Must rule out Herpes Zoster and Herpes Simplex which if left untreated could cause corneal scarring and vision loss.

Often preceded by an upper respiratory tract infection.

Very contagious, good aseptic techniques and Patient education.

Most common etiology of viral conjunctivitis is adenovirus
Typical viral conjunctivitis is often preceded by an upper respiratory tract infection

Mumps: Is a viral infection that primarily affects saliva-producing (salivary) glands that are located near your ears. Mumps can cause swelling in one or both of these glands.

Measles: A highly contagious illness caused by a virus that replicates in the nose and throat of an infected child or adult. Then, when someone with measles coughs, sneezes or talks, infected droplets spray into the air, where other people can inhale them.

Incubation period of 2-14 days, can last 2-4 weeks, contagious for 2 weeks after the second eye becomes infected.

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12
Q

Viral conjuctivitis clinical presentation

A

Red eye with mild to moderate watery discharge.

There may also be Conjunctival swelling, soreness, pain, foreign body sensation, and mild photophobia.

There may also be tenderness around the preauricular node and occasionally subconjunctival hemorrhage.

Generally, one eye will be involved initially, with the other eye becoming involved within days.

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13
Q

Viral conjuctivitis management

A

Generally resolves spontaneously with only symptomatic treatment.

Cool compress, ocular decongestants, artificial tears.

Eye must be stained to rule out Herpes infection and examined with a Slit Lamp if available.

Must be referred to the MO/PA.

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14
Q

Bacterial Conjuctivitis patho

A

Typical pathogens are Staphylococcus and Streptococcus species.

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15
Q

Bacterial Conjuctivitis clinical presentation

A

Symptoms are usually painless and can affect one or both eyes.

Mucopurulent discharge which can cause adherence of the eyelids upon awakening.

Chemosis (Conjunctival edema) is common and the cornea is clear without staining.

Tenderness of the preauricular nodes is usually absent, except in Gonococcal (GC) infections.

Chemosis: Swelling (or edema) of the conjunctiva due to the oozing of exudate from abnormally permeable capillaries. It is a nonspecific sign of eye irritation. The outer surface covering appears to have fluid in it. The conjunctiva becomes swollen and gelatinous in appearance.

Gonococcal: Gonorrhea

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16
Q

Bacterial Conjuctivitis management

A

Warm compress in the morning if eyelids are stuck together.

Consider C+S (upon MO/PA request).

Antibiotic drops/ointments four times daily for 5 to 7 days.

Fluorescein stain to rule out Corneal involvement or herpes.

Aseptic technique and patient education (hand hygiene).

Avoid using contact lenses until resolved.

Refer to MO/PA.

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17
Q

Keratoconjunctivitis Sicca

A

Keratoconjunctivitis Sicca, better known as dry eyes.

The lacrimal function unit is composed of the lacrimal glands, the ocular surface (Cornea & Conjunctiva), meibomian glands, eye lids and sensory motor nerves that connect them.

This unit controls the production of the tear film and responds to environmental, endocrine, and cortical influences.

Tear film is composed of 3 layers;

 1. The mucous layer: Closest to the eye, stabilizes tear film, and removes waste materials. 

 2. The aqueous layer: Thickest part of the tear film, hydrates the mucous layer, supplies oxygen and electrolytes to the ocular surface, and provides antibacterial defense and wound healing. 

 3. The lipid layer: Secreted by the meibomian glands, is the outermost layer of the tear film, slows tear evaporation, enhances tear film spreading, and provides a smooth optical surface.  

Dry eyes have two classifications: Aqueous tear-deficient and evaporative.

What are some of the Occupational risk factors for ‘dry eyes’?

 Answer: 	 Prolonged visual attention to a task
 Tasks that require upward gaze  
 Because they do not blink and or the eye surface area is more exposed

 Environmental factors (such as heat, low humidity, wind,  high air velocity and pollution),
 Diet deficiency with low vitamin A or omega-3 fatty acid.

                     Medication (anticholinergic) Blocks the neurotransmitter acetylcholine in the central and the peripheral nervous system. These agents inhibit parasympathetic nerve impulses by selectively blocking the binding                         	of the neurotransmitter acetylcholine to its receptor in nerve cells
 Contact lens
 Age
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18
Q

Keratoconjunctivitis Sicca clinical presentation

A

Signs/Symptoms: Foreign body sensation, burning/itchy/tired sensation, photophobia, blurred vision, redness, discomfort, and difficulty moving lids. Some patients may complain of increase tearing as well.

19
Q

Keratoconjunctivitis Sicca

A

Treatment: Avoidance of any allergens that may cause dry eyes, decrease use of contact lenses, refresh tears or ocular lubricants.

Learning support (CREST): The patient’s history is key. This condition can lead you in the wrong direction and cause you to treat a different condition even though the presentations are similar. Be sure to educate your contact lens wearers about proper treatment and cleaning of the contact lens. Don’t be afraid to add “to wear sunglasses as needed” on the chit. This will help the eyes recover.

20
Q

Keratoconjunctivitis Sicca patho

A

Better known as Dry Eye Disease (DED).

A malfunction disease of the tears and ocular surface resulting
in symptoms.

Has 2 classifications:

Aqueous tear deficient dry eye (inadequate tear production).

Evaporative dry eye (abnormality of tear production).

C-434 Pg 128.

Aqueous tear-deficient dry eyes: With this type of dry eyes, the lacrimal gland does not produce enough tears to keep the entire conjunctiva and cornea covered by a complete layer of tears. This is the most common type among postmenopausal women. Dry eyes are common inSjogren (show-grun) Syndrome.

Sjogren Syndrome is an immune system disorders, such as rheumatoid arthritis and lupus. In Sjogren’s syndrome, the mucous membranes and moisture-secreting glands of your eyes and mouth are usually affected first — resulting in decreased tears and saliva.

Evaporative: Dry eyes may also be due to an abnormality of tear composition that results in rapid evaporation of the tears. Although the tear gland produces a sufficient amount of tears, the rate of evaporation is so rapid that the entire surface of the eye cannot be kept covered with a complete layer of tears during certain activities or in certain environments.

21
Q

Keratoconjunctivitis Sicca

A

Foreign body sensation (sandy/gritty feeling),
Burning, itchy, tired sensation,
Photophobia,
Blurred vision,
Redness,
Discomfort,
Difficulty moving lids, and
Increase tearing in windy conditions or when concentrating on
tasks like reading or doing computer work.

22
Q

Keratoconjunctivitis Sicca

A

Reducing or eliminating environmental factors.

Proper education on use of contact lenses.

Artificial tears, ocular lubricants, or prescription options (consult
with MO/PA).

Continue to monitor and adjust treatments as required. May
require a referral to ophthalmology.

23
Q

Corneal Abrasions

A

Corneal abrasions are very serious and painful.

Intact corneal epithelium is resistant to infection(s), but when
damaged, it causes an entry for bacteria, viruses, and fungi.

If not treated swiftly and aggressively they will develop into an
associated inflammatory Iritis.

Healing time is usually within 24-48 hrs.

24
Q

Corneal abrasion clinical presentTION

A

FBS

Photophobia

Redness

Swelling

Pain

25
Q

Corneal Abrasions Treatment

A

Pain relief (may be required prior to examination).

Infection prevention.

Caution with eye patch (some patients feel comfort with a patch
but decrease depth perception so they should not drive a car.
Their use may also promote growth of bacteria).

Flourescein stain to confirm and examine with a Slit lamp.

Requires referral to MO/PA and should include Ophthalmology.

26
Q

Blepharitis patho

A

Inflammation of the eyelash follicles along the edge of the
eyelid.

The disorder is associated with seborrheic dermatitis, atopic
dermatitis, acne rosacea, and occasionally eyelash infestation
with lice.

Long-term complications may include physical damage to the
eyelids and cornea.

27
Q

Blepharitis presentation

A

Conjunctival injection.
Crusting.
Swollen, and pruritic eyelids.
Occasional complaint of eye pain.
Chalazion or Hordeolum may also be present.
Foreign Body Sensation (sandy or gritty feeling worse on wakening).

28
Q

Blepharitis management

A

For optimal outcomes, treatment of all other underlying conditions are
necessary.

Encourage patients to maintain a long-term lid hygiene regimen (warm
compresses, gentle scrubbing of the eyelid margins and in some cases
mechanical expression but this is usually done by an ophthalmologist).

In severe cases antibiotic drops or ointment may be required.

Aseptic technique and patient education.

Refer to MO/PA/Ophthalmologist.

29
Q

Hyphema patho

A

Blood or blood clots in the anterior chamber of the eye.

Traumatic and spontaneous

Traumatic: usually results from a ruptured iris root vessel.

Spontaneous: Usually associated with sickle cell disease

30
Q

Hyphema clinical presentation

A

Blurred vision

Pain and photophobia.

Blood may be visible behind the lower part of the cornea in the
anterior chamber of the eye.

31
Q

Hyphema management

A

Ask if the patient is on any anticoagulant, anti-platelet
medications or if they have a history of bleeding disorders.

Must be seen by an ophthalmologist so refer to MO/PA.

Elevate the patients head to promote settling of suspended
RBC’s. This will prevent occlusion of the trabecular meshwork.

Avoid pupil activity (Dilation of pupils, use of eye patch, put in
dark room).

Pupillary play: Constriction and dilation movements of the iris in response to changing lighting, which can stretch the involved iris vessel causing additional bleeding

Post-traumatic hyphema is an ophthalmologic emergency that can result in permanent vision loss. Accumulation of blood in the anterior chamber causes trabecular meshwork obstruction, thereby elevating IOP.

Trabecular meshwork: is an area of tissue in the eyelocated around the base of the cornea, near the ciliary body, and is responsible for draining theaqueous humorfrom the eye via theanterior chamber

32
Q

Eye disorders :General rules

A

Always have Pt RTC for follow up within 24hrs
Always do a Visual acuity before and after Tx
Involve an SMA (because it is an eye)
Always use safety equipment to protect eyes

33
Q

Treatment: Foreign body

A

Have Pt identify location (top/bottom)
Gently tilt eyelid back
If item is easily identifiable:
Only proceed if it is on surface
Use a soft, wetted, cotton tipped applicator to remove.
Gently let eye stream flow into eye and under lid.
Re-inspect. Repeat as needed.

34
Q

Condition: Open/Ruptured Globe

A

Cause: Trauma to eye or skull
S/S: Visible, or non visible tears or openings of eye. May be present with hyphema. Changes to pupil shape.
Often identifiable on inspection. May or may not have hyphema in affected eye.

Discuss: Should you fluoresce this eye?
Answer: No. Chemical drops may cause more issues and impede healing. Transfer to higher level of care follow Med Tech QL5 protocol.

Cover, keep the eye closed if possible. ORAL/IM/IV Antibiotics as per QL5 Protocol or SMA order.

Avoid pressure on the eye. Use a hard eye cover/shield with sterile liner when possible to keep clean and avoid pressure.
MO may fluoresce eye but they will do so in controlled conditions to determine where the opening may be.

*** Always have a high index of suspicion that there is an open or ruptured globe if:
Ecchymosis of the eyelids (black eye)
Laceration of the eyelids
orbital hemorrhage
# of the ethmoid bone / la fort #
blowout fractures of the floor or the orbit
corneal abrasions,
corneal & conjunctival foreign bodies.

35
Q

Condition: Retinal Detachment

A

Cause: Trauma, Glaucoma, various disease processes, congenital causes. Simply put, a tear occurs due to thinning or trauma, and fluid gets behind the retina and it detaches.
S/S: Often painless, may be described like ‘curtain is lowered over eye’, sparkles or lights seen.
Special Test: Fundoscopy. Request MO / Optho does a slit lamp test.
Hx: Common factors are that Pt is nearsighted, over 50, may have had cataract surgery. (C21 - p. 182)
Tx: SMA will likely refer out to laser or surgery to repair tear to stop fluid from getting behind the retina.
Initial slit lamp or fundoscopy may show ‘tobacco dust sign’ also known as schaffer’s sign. Looks like floating dust in vitreous humor from pigments released.

Exam: Determine that the central vision is still good. Use visual fields by confrontation test, (C18 P. 222) to determine if the macula is still attached.

Field Note: If possible transport pt with head positioned so that the detached portion of retina may temporarily fall back with aid of gravity. (difficult to do in many cases as the detachment is often on the superior aspect of the eye

36
Q

Condition: Glaucoma

A

DISCUSS:The eyeball is basically a container that is constantly filling, and also constantly draining. In glaucoma the drain gets clogged, then the intraocular pressure builds up and may increase pressure on the optic nerve, and blood vessels that exit the eye.
This blockage can be caused by age and or a hereditary condition.

Usually found in older age groups. >50 year old. Particularly farsighted individuals.
Usually an asymptomatic disease not noticed until vision changes.

Hx: Acute or recent onset of eye pain. hx or age will often indicate
S/S: Pt may have ;read eye’, cornea can be described as ‘steamy’ in appearance. An pupil may be dilated. Eye is hard on palpation in later stages (C2 - P. 177) Rapid onset of severe pain and profound visual loss with halos around lights is often noted in severe glaucoma. Pt usually complains of blurred vision, halos, and lights.

There are little to no lifestyle or preventative measures that can avoid this SMA will prescribe medication and drops to reduce Intraocular pressure.

Discuss:Cupping can be measured by determining how large the light spot in the center of the optic nerve is. A rule of thumb is that it should be ⅓ of the height of the optic disk.

37
Q

Condition: Diabetes

A

Discuss:While diabetes will be discussed later during endocrine classes, it is worth understanding what retinopathy looks like in a diabetic pt when compared to that of a healthy pt.
This is a good example or retinopathy for you to look for during the fundoscopy of patients.

We will discuss diabetes later during the endocrine portion of the course, it is only notable during this portion of the course as it may be relevant with patients who have vision changes and a Hx of Diabetes.

Reference: C18 - P. 271-277 - Examples of damaged retinas as seen in various conditions.

38
Q

Special Tests: Visual Fields by Conf.

A

Discuss:
Visual fields by confrontation can be conducted multiple ways. The gross assessment of the visual fields can be initially assessed by the static finger ‘wiggle test’.
This test checks which quadrants/areas in the Pt’s field of vision are affected.

If you need to test further you can repeat the process and isolate one eye and repeat on each eye.

We will demonstrate this test in the Ward later.

Reference: C18 - Page 2222-223

39
Q

Special Tests: Fundoscopy

A

Discuss:
As discussed previously, the focused eye exam will require a fundoscopy. This is the method by which we will look at the retina, specifically the optic nerve. We have seen what the back of the eye (fundus/retina) looks like in previous slides.

We will demonstrate this test in the Ward later.

Reference: C18 - Page 228-229

40
Q

Discussion: Chief Complaints

A

Vision loss (sudden vs prolonged) (transient vs prolonged) (central vs peripheral) (binocular vs monocular)
Ptosis (Drooping of upper eyelid)
Diplopia (Double Vision)
Tearing (Lacrimations)
Dryness (Xeros)
Foreign Body Sensation
Pruritus (Itchyness)
Discharge
Eyelid crusting
Eyelid swelling
Floaters in vision
Flashes of light
Halos
Photophobia (Discomfort to light)
Headaches

NOTES:
Discuss each point with students and what conditions they think may be related to the CC or signs and symptoms.
Many of these will be multiple conditions. Creates discussion. Get students to name a few for each CC

41
Q

Other Conditions of Note

A

Graves’ ophthalmopathy
Ptosis due to stroke/nerve damage
Giant Cell Arteritis
Retinal artery occlusion
Cataracts
Many more…

Ptosis can be caused by neuro conditions. More will be discussed during the neurological lessons.

Giant Cell arteritis is a condition that may lead to loss of vision due to inflammation of arterial walls in the temporal region. Occurs more often in Pt’s >50 and linked to polymyalgia rheumatica.

Retinal artery occlusion: A blockage in the main artery leading to the eye. May appear on fundoscopic inspection.

Cataracts are a clouding of the lens of the eye. Usually developed slowly over time, usually with age. Usually indicated by a lack of red reflex during fundoscopy.

42
Q

Patient Assessment Model

A

Focused Hx
Focused Exam
Visual acuity (Snellen Chart)
Fluorescein + Woods Lamp (if indicated)
Refer/Discuss with MO

Discuss:
Focused exam format is to determine if condition is emergent. A full EENT exam should always be conducted.
Always do a Visual Acuity for an eye complaint.

NOTES:
On the ward we will be practicing a focused exam only to allow students time to practice hx taking, special tests, and skills specific to the eye.

43
Q
A

<SHORT>

Instructor will provide two to three separate scenarios and students will take turns working through CHLORIDE AAA PMASIF to practice hx taking and consolidate information learned. Have students practice using VINDICATE to offer DDx.

Focus on Hx, Dx/DDx and Tx plan

References: Bates Guide to History Taking – 7th Edition, L.S. Bickley; Pages 35 -41
</SHORT>