Eye Care - Conjunctivitis Flashcards

1
Q

what is a think, translucent, relatively elastic tissue layer that lines the inside of the eyelids and the anterior aspect of the globe?

A

conjunctiva

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2
Q

what is a general term that refers to any inflammatory condition of the membrane that lines the inside of the eyelids and covers the exposed surface of the sclera?

A

conjunctivitis

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3
Q

what are 3 types of bacterial conjunctivitis?

A

hyperacute, acute, and chronic

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4
Q

what are common causes of bacterial conjunctivitis in neonates?

A

Chlamydia trachomatis, Staphylococcus aureus, Haemophilus influenzae, Streptococcus pneumoniae, Neisseria gonorrhoeae, Neisseria meningitidis

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5
Q

what are common causes of bacterial conjunctivitis in children?

A

H. influenzae, S. pneumoniae, S. aureus

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6
Q

what are common causes of bacterial conjunctivitis in adult?

A

S. aureus, coagulase-negative Staphylococcus organisms, H. influenzae, S. pneumoniae, N. gonorrhoeae, N. meningitidis, C. trachomatis

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7
Q

what are the common cause of viral conjunctivitis?

A

Adenovirus

Herpes simplex virus

Human papillomavirus

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8
Q

what are other Common causes of conjunctivitis (not bacterial or viral)

A

immunologic,
chemical or irritative,
associated with dermatologic conditions (ocular rosacea, psoriasis, stevens-johnson syndrome),
associated with systemic disease (thyroid disease, kawasaki disease), lacrimal system infections (canaliculitis, dacryocystitis)

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9
Q

what is the most common causative organism of acute bacterial conjunctivitis ?

A

Staphylococcus aureus;
but Streptococcus pneumoniae and H. influenzae are also common especially in kids

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10
Q

what are nonpharmacologic measure for acute bacterial conjunctivitis?

A

prevent contamination - hand-wash, avoid direct hand-to-eye contact, separate towel use;

soak with a warm compress;

irrigate with sterile saline or a commercial eye wash product;

no contact lens wear - seek medical advice;

if you use eye drops for other indication (e.g. glaucoma or dry eye), replace the eye drop bottles

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11
Q

when do you recommend polysporin eye drop?

A

mild cases of bacterial conjunctivitis in adults - continue treatment for 2 days after symptoms have resolved;

if not better in 2 days, refer or AB Rx

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12
Q

what is empiric tx with broad spectrum AB drops for acute bacterial conjunctivitis?

A

trimethoprim/polymyxin B;
erythromycin ophthalmic ointment;
fusidic acid ophthalmic drops

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13
Q

according to bugs and drugs - what is adult ophthalmic for acute bacterial conjunctivitis?

A

polysporin qid 7-10 days OR
tobramycin 0.3% qid 7-10 days

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14
Q

according to bugs and drugs - what is infant/kids ophthalmic for acute bacterial conjunctivitis?

A

bacitricin-polymyxin B qid 7-10 days OR
erythromycin 0.5% qid 7-10 days

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15
Q

if patient wears contact lens, what is Rx for acute bacterial conjunctivitis? why?

A

cipro 0.3% or tobramycin 0.3% -
need pseudomonas coverage

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16
Q

what is side effect of tobramycin eye drop for prolonged use (>7 days) ?

A

toxicity to the corneal epithelium

17
Q

what is characterized by a copious, yellow-green purulent discharge, redness, irritation and tenderness to palpation, a severe, sight-threatening ocular infection caused by Neisseria gonorrhoeae or Neisseria meningitidis?

A

hyperacute bacterial conjunctivitis

18
Q

what is chronic bacterial conjunctivitis?

A

if symptoms lasts 4 weeks or longer;
often associated with blepharitis, and is sometimes found in conjunction with facial seborrhea, acne rosacea, nasolacrimal duct obstruction or chronic dacryocystitis

19
Q

what is the common cause of chronic bacterial conjunctivitis?

A

S. aureus and Moraxella lacunata;

In sexually active adults, chronic bacterial conjunctivitis can be a manifestation of a sexually transmitted infection involving Chlamydia trachomatis

20
Q

what is nonpharmacologic therapy for chronic bact conjunc?

A

eyelid hygiene, warm compress as daily routine;
no contaminated facial-care products and makeup

21
Q

what are RX for chronic bacterial conjunc?

A

topical AB during periods of exacerbation;

doxycycline or erythromycin oral - if associated with meibomian gland dysfunction or severe acne rosacea;

topical metronidazole for acne rosacea may also ameliorate associated conjunctivitis

22
Q

what are usual symptom of viral conjunctivitis?

A

red eye, watery discharge, conjunctival swelling, foreign body sensation and mild photophobia;

may be tenderness around the preauricular node;

Occasionally, patients may have subconjunctival hemorrhage

23
Q

The most common causative organism of viral conjunctivitis is ?

A

adenovirus

24
Q

what is treatment for viral conjunctivitis?

A

supportive - cold compresses, avoid direct contact with others for at least 10 days after the onset,

handwashing with soap and water (not sanitizer), separate towel, kids kept out of school until no ocular discharge (approx 1 week)

25
what are non-pharm measure for allergic conjunctivitis?
avoid allergen; wraparound eyeglasses; cold compress;
26
what are the 1st line pharm measure for allergic conjunctivitis?
1st line: - ocular lubricants - wash out allergnes - use non-preservative ones; - saline or commercial eyewashes; - refrigerate may improve their soothing effect
27
what are some ophthalmic decongestants?
naphazoline, phenylephrine, tetrahydrozoline
28
how to counsel the use of eye decongestants? how decongestants work?
use less than 10 days; 2nd line option for mild-moderate seasonal allergic conjunctivitis; vasoconstriction
29
what is the contraindication of eye decongestants?
angle-closure glaucoma
30
what is brimonidine and its use? how does brimonidine help with allergic conjunctivitis?
a selective alpha2-adrenergic receptor agonist typically used for glaucoma; available without a prescription in a lower concentration (0.025%) for the treatment of red eye; brimonidine does not appear to cause significant rebound hyperemia or tachyphylaxis
31
Ophthalmic antihistamines (in combo with decongestants) vs. oral H1 antihistamines - what do you prefer for allergic conjunctivitis?
ophthalmic preferred because they act faster and are less drying
32
what is Mast cell stabilizers?
prevent degranulation of mast cells and are useful in both SAC and PAC as they treat the late phase of the allergic response
33
how to use mast cell stabilizers?
before allergy season starts - takes up to 10 days for maximum effect
34
what are mast cell stabilier products?
lodoxamide (Alomide - 1-2 drops qid); sodium cromoglycate 1-2 drops 4-6 times/day; may take 2-3 days to see symptom improvement
35
Agents that have both antihistaminic and mast cell–stabilizing properties? what are advantages?
olopatadine, ketotifen; relieve itching quickly while providing long-term activity against ocular irritation by allergens
36
what do Nonsteroidal anti-inflammatory eye drops do? what is the limitation?
decrease the amount of ocular itching and conjunctival redness in allergic conjunctivitis; limit to short-term use to avoid serious corneal effects such as keratitis, ulceration or even corneal perforation (Patients at increased risk of corneal effects include those with dry eye syndrome and those recovering from recent surgery)
37