Eye Flashcards
What are the 5 histological layers of the cornea?
1=stratified squamous non-keratinsed epithelium
2=Bowman’s membrane
3=Stroma (regulary arranged collagen)
4=Descemet’s layer
5=endothelium
What function does the endothelium of the cornea have?
Has a pump that actively keeps out aqueous humor
What is the pathway of aqueous humor
the ciliary body releases aqueous humor into the anterior chamber, at the angle of the anterior chamber is drains through the trabecular meshwork, it then reaches a little tube known as the schlemm’s canal
Why is the fovea centralis have max visual acuity?
packed with cones
Describe the lens of the eye
A transparent, crystalline biconvex structure which is suspended by zonules from the ciliary body
What is lens opacification called?
cataract
Function of tear film
Cornea moist, wash away particulate foreign bodies, contains antibodies and lysozymes, smooths outer surface of cornea- so smooth surface for refraction
the 3 layers of the tear film?
layer 1= mucinous layer overlying corneal epithelium
layer 2= aqueous layer
layer 3= oily layer
What nerve stimulates secretion of tears into conjunctival sac?
parasympathetic- facial nerve
What distributes a tear film across the eye?
when you blink the sharp lower border of the upper eyelid distributes tear film evenly
What stimulates you to blink?
when your eyelids are open, the aqueous component of tears begin to evaporate, and the oily layer becomes to close to the mucin layer.
When these 2 layers touch the tear film breaks up and your eyelid is stimulated to blink
What is refraction?
bending of light when it passes from one optical medium to another
What is refraction in relation to the eye?
light waves from an object bend at the cornea, they are bent some more at the lens to form a clear image on the retina.
What is accommodation
The change that occurs in eyes when it changes focus from a distant (infinity) to a close object (20cm)
When does a lens thicken and what does this help the eye do?
A lens thickens during accomodation to help focus on closer objects
Describe the steps of a lens thickening
Ciliary muscles contracts making the ciliary body bulge, space in the middle decreases, suspensory ligaments become lax, lens is no longer under stretch and lens becomes thicker
What is the 2nd step on accommodation
pupil constriction via pupillary constrictor muscle around the border of the pupil, via parasympathetic (CNIII) innervation
What is the 3rd step of accommodation
eyes convergence- when you focus on a close object out eyes have to both turn in medially using the medial recti muscles
What is the name for perfect vision?
emmetrope
What is myopia?
shortsightedness
distant objects look hazy
What is phototransduction?
conversion of light energy to an electrochemical response by the photoreceptors (rods and cones)
What is the visual pigment in rods?
in the lamellae cell membrane of the rod is a visual pigment called rhodopsin
What is the visual pigment in cones?
in the lamellae cell membrane of cones is visual pigment called opsins S, M and L
What happens when light hits the visual pigment?
11-cis retinal sits in the opsins (made from dietary vit-A), when light falls on 11-cis retinal, it isomerises into all-trans retinal
all trans retinal cannot fit in the opsin, so rhodopsin spilts resulting in bleeching
What does bleaching of visual pigment cause?
Causes a phototransdution cascade, this is a cascade of reactions causing hyperpolarisation, transmitting an impulse, which becomes an action potential in the optic cells
What role does vitamin A play in visual pigment?
visual pigment regeneration
signs of vitamin A deficiency in the eye
Bitot’s spot on conjunctiva, corneal ulceration, corneal melting
How can your visual field be tested?
by confrontation test or automated perimetry
Where do fibres from the optic tract synapse?
fibres from the optic tract synapse at the Lateral geniculate body of the thalamus
Describe the steps of a visual pathway
All fibres from the eye pass through the optic nerve to the optic chiasma,
the nasal fibres cross to the opposite side, thus the optic tract contains fibres from the temporal half of the ipsilateral eye and the corssed-over nasal fibres from the contralateral eye .
fibres from the optic tract synapse at the LGB of the thalamus.
optic radiation passes behind the internal capsule to reach the primary visual cortex in the occipital lobe
What causes contralateral homonymous hemianopia?
right optic tract damage, optic radiation damage
What causes bitemporal hemianopia
optic chiasma disrupted in the middle
Role of intrinsic muscles?
control pupil diameter and help alter lens curvature to enable us to see near objects
Role of extrinsic muscles?
move the eye
What do the recti muscles arise from?
they arise from the apex of the orbit from an annular fibrous ring
Where does the superior oblique muscle arise from
from the roof of the orbit posteriorly
Where does the inferior oblique muscle arise from
the floor of the orbit anteriorly
what does LPS stand for and what does this muscle do?
levator palpebrae superioris
this muscle elevates the eyelids
What does strabismus mean
squint
Types of squint?
Esotropia- manifest convergent squint, one eye is deviated inward
Exotropia- manifest divergent squint, one or both eyes look outward
Functional consequences of squint?
Amblyopia, diplopia
What is amblyopia?
lazy eye
brain supresses the image of 1 eye leading to poor vision in that eye without pathology