Eye Flashcards
The painful structures of eye are……, while painless structures are …….
Cornea, iris, ciliary body
Lens, vitreuous body, choroid, retina
Ant 1/6 of eye is protected by….., post 5/6 of eye is protected by…..
Eyelid
Bony orbit
Center and effert of corneal reflex
Midbrain (suprior colluiculus)
Efferent, facial nerve of both sides
Compare Menace & Dazzle reflex
M, blinking after moving object very close to the eye
D, shining bright ligh t in the eye
Explain types of tear secretion
Basal secretion
Reflex secretion due to corneal/conjunctival irritation afferent is by ophthalmic n and efferent is by parasympathetic (facialn.)
Psychic tears: inc tear secretion by emotion: produced by activation of arasymp supply
Lipid layer of tears is secreted by ……, water layer by……. Which contains……proteins. Mucos layer is secreted by…….
Meibomian glands
Lacrimal glands, lactoferrin/IgA
Gobet cells of conjunctiva
Function of mucous in tear film
Make the corneal and conjuctival surface hydrophilic so tears can spread homogenously over surface
Enumerate functions of tear film
Optimizing corneal optic properties, cleansing, healing effects (supply WBCs), nutritive, protective, lubricant
Mention causes of dry eye
Dec tear secretion, vitamin A deficiency, impaired lid function (exposure keratitis)
Write formula for refractive index
RI= Velocity of light rays in air/velocity of light rays in medium
…..has highest refractive index in eye, while……. causes most refraction of light
Lens
Cornea
Mention factors controlling degree of refraction of light
- Refractive index of medium
- Angle of incidence on interface
- Degree of curvature
Define focal length
The distance between center of lens & focal point
Write formula for lens power
Lens power=1/focal length in meter OR 1/object distance+1/image distance
The central point of the eye as a whole lies……
17 mm in front pf the retina
The total refractive power of the human eye is…..
50-60 dipoters
GR: Most refractive power comes from cornea not the lens
Because the greatest difference in refractive index is at the air-cornea interface, so most refraction occurs there while lens is surrounded by aqueous & vitreous humors which have nearly equal refractive index
Describe image orientation of the retina
Retina, images are inverted but they are processed upright by the visual cortex, if retinal images are turned right side up by means of special lenses, the object viewed would look upside down.
Enumerate functions of the cornea
- Transparent structure allows light entry to eye
2, most powerful refractive medium of the eye - Regular curvature important in formation of sharp retinal images
- Has protective function
Describe nutritional supply of the cornea
Diffusion from aqueous humor, limbal capillaries, tear film (85% of O2 needs is taken from tear film)
Mention causes of corneal transparency
Non-keratinized, avascular, substantia propria fibers are regularly arranged, nerves are unmyelinated, tear film keeps cornea moist and prevents dryness, relative corneal dehydration.
Enumerate causes of corneal dehydration
Both epithelim & endothelium act as barriers to prevent excess flow of water to stroma
1. Surface epithelium is connected by tight junctions and has Na/K pumps forming hypo-osmotic stroma & hyperosmotic aqueous humor
2. Endothelial cells have Na-K pump, carbonic anhydrase and Na-H exchanger that maintain low Na conc and consequently water in substantia propria
Enumerate causes of corneal opacity
- Corneal injury that reaches Bowman’s capsule
- Vitamin A def results in xerophthalmia and corneal keratinization
- Corneal vascularization
Functions of the choroid
The choroid’s pigment absorb extra light. That is not absorbed by photoreceptors to prevent blurring of vision
Choroidal bv provide rerina with O2 and nutrients
Secretory part of ciliary body is……while contractile part is…..
Ciliary process
Ciliary muscle
Describe active secretion mechanism of aqueous humor
Major contributor to aqueous formation (80-90%), carried out by non-pigmented epithelial cells as they contain Na-K pumps which actively pumps Na while Cl and water follow passively. Also contains carbonic anhydrase which helps secretion of HCO3 to intercellular spaces .
Describe circulation & drainage of aqueous humor
Episcleral outflow (90%] it passes through trabecular meshwork to canal of Schlemm to the episcleral veins.
Uveo-scleral outflow (10%): passes through ciliary body to be absorbed by bc, scoeral wall to the periocular orbital tissues .
Mention functions of aqueous humor
Maintain IOP, supplies nutrition and drains waste of avascular structures, one of the refractive media of the eye
IOP is….measured by…..
12-20 mmHg
Tonometer
Enumerate functions of IOP
Maintain spheroid shape of eye, exert two forces on normal focusing mechanism, pressure flattening force on lens surface and stretching force on the lens. Maintain lens during rest.
Compare oper & closed angle glaucoma
O, is caused by damage, sclerosis or obstruction of trabecular meshwork which impairs drainage while the irido-corneal angle is opened.
C, closure of irido-corneal angle by root of iris
Mention results of glaucoma
- Failure of accomodation
- Compression of optic n at optic disc leading to optic atrophy, concentric visual field narrowing and finally blindness
- Headache
The power of the lens at rest is…..while at full accomodation is……, that of cornea is…
20 diopters
34 diopters
40 diopters
Enumerate lens functions
It is an important refractive medium (1/3 of eye power)
It has an important role for near vision (accomodation reflex)
The anterior surface of lens compared to pasterior has…….
Higher refractive index with less curvature
What are causes of lens transparency?
It is a avascualr, lacks nerves, fibers are arranegd in regular manner with little extracellular space, high conc of glutathione which keep protein reduced, protein oxidation leads to aggregation and loss of transparency, it contains Na/K ATPase pumps in lens epithelium that extrude Na & Ca and prevent lens swelling & opacification.
Enumerate causes of cataract
Congenital
Old age, due to accumulation of low molecular weight polypeptides in the lens
Exposure to UV or X-rays
1ry to diseases as DM aschigh glucose level activates polyol pathway and leads to sorbitol accumulation. Sorbitol has high osmotic power.
Describe aim & mechanism of bilateral convergence of both eye
This allows the 2 images of the near object to fall on the fovea centralis of both retinas to fall on 2 corresponding points in both eyes and prevent diplopia.
M, contraction of 2 medial recti muscles
Describe the aim of bilateral miosis
Prevents light falling on peripheral parts of the lens so light falls on center of lens. This prevents spherical & chromatic aberration.
Define:
1. Spherical aberration
2. Chromatic aberration
- It is the formation of blurred image due to inability of lens to collect all the light rays into a single focal point. The refractive index of the peripheral parts is different from the central parts resulting ij different refraction and different foci.
- The peripheral parts of lens act as a prism which analyses white light inti spectral components
Describe aim & mechanism of bilateral accomodation
A, increase the power of the lens to collect divergent light rays so the image of object is shifted to the retina.
M, Ciliary muscle contracts, ciliary body is pulled forward and inward, distance netween edges of ciliary body dec, lens ligament relaxes, lens springs into more convex shape, anterior curvature esp inc.
Mention the center and efferent of accomodation refkex
C, superior colliculus in midbrain sends signals to Edinger Westphal n
E, CN III:
1. Parasympathetic fibers from EWN relay in ciliary ganglion for constrictir pupillae & ciliary muscle
2. Somatic fibers from area 19 to area 8 stimulate somatic part of CN III fir MR
In Purkinje-Sasor images, the small upright image is from……, the large upright image is from……, the small inverted image is from…..
What happens when subject looks at nearer object & what can you deduce?
Cornea (convex mirror)
Anterior surface of the lens (convex mirror)
Posterior surface of the lens (Concave mirror)
The middle image of ant lens dec in size the others remian constant
Accomodation changes curvature of anterior lens
Define:
1. Accomodation amplitude
2. Accomodation range
- It is thexdifference between refractive power of the eye when accomodation is relxed and its power when accomodation is maximum
- It is the distance between the far point of distinct vision (fully relaxed accomodation).and near point of distinct vision
Define:
1. Punctum proximum
2. Punctum remotum
- It is the nearest point to the eye at which an object can be seen clearly with accomodation
- It is the farthest point from the eye at which the onject can be seen clearly when accomodation is fully relaxed
Define:
1. Myopia
2. Hypermetropia
- Refractive condition the eye in which parallel rays come to a point of focus in front of the retina while accomodation is at rest, close objects are seen clearly but distant ones are blurred.
- Parallel ray cone to a point of focus behind the retina while accomodation is fully relaxed. Distant objects seen perfectly but not close objects
Describe long-term effects of hypermetropia
Headache & fatigue due to continuous contraction of MR, may also lead to medial squint in children.
Compare myopia & hypermetropia with respect: far point, near point, range of accomodation, ciliary muscle
Myopia: limited, nearer than normal, decreased, poorly developed
Hypermetropia: normal (with accomodation), farther than normal, decreased, well-developed
(IN ORDER OF THE QUESTION)
Compare myopia & hypermetropia with respect:causes & correction
Myopia: long eyeball (each 1mm leads to -3D) OR inc refractive power of lens due to ciliary muscle spasm, lens dislocation, or inc corneal curvature (keratoconus), corrected by concave spherical lens.
Hypermetropia: short eyeball (each 1mm leads to +3D) OR refractive power of lens dec due to abnormal flat lens or paralysis of ciliary muscle or dec corneal curvature (cornea plans), corrected by convex spherical lens.
What happens in presbypoia?
-Gradual loss of accomodation with aging
- The near point recedes away from the eye
-Far point does not change
-Accomodation power & range decrease
Causes of prebyopia & correct.
- Loss of lens elasticity
- Loss of elasticity of choroid
- Liquefaction of vitreous causing loss of lens support
Coorected by convex lens for near vision only
Describe general feature of astigmatism
Refractive condition of the eye in which parallel rays come into different foci resulting blurred image, the refractive power of the eye is not the same in different meridians. Curvature of lens/cornea is not equal or uniform.
Enumerate types of regular astigmatism +definition + correction
Simple: one meridian is emmetropic the other is ametropic.
Cylindrical lens its axis is placed at right angles to diseased meridian
Compound: both meridians are ametropic with different degrees of error.
Sphero-cylindrical lens correction
Mixed: one meridian is myopic the other is hypermetropic, corrected as previous.