Extra Questions from Study Materials Flashcards

1
Q

Mnemonic for potency of glucocorticoids

A

“Cold Hands Palpate My Dead Body” (least to most potent)

Cortisone -> hydrocortisone -> prednisone/prednisolone –> methylprednisolone –> dexamethasone –> betamethasone

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2
Q

Thyroid and adrenal disorders – what do you replete in what order

A

Glucocorticoid then mineralcorticoid and last thyroid replacement

T4 should not be administered until adrenal function, including ACTH reserve, have been evaluated and either found to be normal or treated. In patients with coexisting hypothyroidism and hypoadrenalism, treatment of hypothyroidism alone may increase the clearance of the little cortisol produced, increasing the severity of the cortisol deficiency

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3
Q

Differential of tall and primary amenorrhea

A

Complete AIS – no uterus

Complete 46, XY GD – (DAX dup) - uterus

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4
Q

Most common malignancy associated with IVF?

A
  • Borderline
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5
Q
A
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6
Q

Hypercarotenemia associated with what HPO axis anomaly?

A

Hypo hypo (anorexia)

Also hypothyroidism, diabetes

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7
Q

Causes of falsely elevated cortisol

A

Obesity

Late night salivary cortisol test: licorice, chewing tobacco, smoking, shift workers, night owls

Dexa suppression test: OCPs (increase CBG and assay measures total cortisol), anticonvulsant medication (accelerates metabolism of dexamethasone)

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8
Q

Normal BMI and PCOS, best treatment?

Clomid, metformin, or both

A

Clomid

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9
Q

Most likely to have heterophilic antibodies?

A

Vet tech

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10
Q

Kappa statistic

A

Measure of agreement between 2 observers (-1.0 to +1.0). Perfect agreement = 1.0 If agreement is what would be expected by chance alone then = 0. If degree of agreement less than what would be expected by chance then < 0.

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