EXPANDED PROGRAM ON IMMUNIZATION Flashcards
- Established in 1976
- Legal Basis: Presidential Decree 996 (PD 996)
- To ensure that infants/children and mothers have access to routinely recommended infant/childhood vaccines.
- Six vaccine preventable diseases were initially included in the EPI: TB, poliomyelitis, diphtheria, tetanus, pertussis & measles
EXPANDED PROGRAM ON IMMUNIZATION
- Compulsory Immunization against Hepatitis B
- Provided for compulsory immunization against Hepatitis B for infants & children below 8 years old.
- Provided for hepatitis B immunization within 24 hours after birth of babies of women with hepatitis B
REPUBLIC ACT OF 7846 (RA 7846)
- National Immunization Program
- Mandatory Infants and Children Health Immunization Act of 2011
- Mandates basic immunization covering the vaccine-preventable diseases
Goals of the Program:
1. To immunize all infants/children against the most common vaccine-preventable diseases.
2. To sustain the polio-free status of the Philippines.
3. To eliminate measles infection.
4. To eliminate maternal and neonatal tetanus.
5. To control diphtheria, pertussis, hepatitis B, & German measles.
6. To prevent extrapulmonary TB among children.
REPUBLIC ACT OF 10152
(RA 10152)
Eligible Population
0 – 12 MONTHS (newborn/infants)
Principles
- Epidemiological Situation
- Mass Approach
- Basic Health Service
- “weakened”
- Very effective, provides lifelong protection in 1 or 2 shots.
- Can’t give to weak immune system (like children with HIV infection)
Vaccine: - Bacteria: Tuberculosis (BCG)
- Virus: Oral Polio Vax., measles, Rotavirus, Yellow fever
Ex.: - MMR vaccine (measles, mumps & rubella)
- Anti-Measles Vaccine / Measles Containing Vaccine
- Rotavirus
- Smallpox
- Chickenpox
Attenuated Vaccine - Live but altered (LAV)
- Safer than LAV
- Less effective than LAV
- Not lifetime protection. Needs multiple doses over time
Vaccine: - Bacteria: Whole-cell pertussis (wP)
- Virus: Inactivated Polio Virus (IPV
Ex.: - wP – whole cell Pertussis
- IPV – inactivated polio vaccine
Inactivated Vaccine - Killed
- Safe, can’t cause disease, no possibility of reversion to virulence
- Require several doses, need adjuvant
Vaccine: - Bacteria: Tetanus (TT)
- Diphtheria toxoid
Toxoid Vaccine
- Create response against the molecules in the pathogen’s capsule
Ex.:
- Haemophilus influenzae type b conjugate (Hib)
- Pneumococcal conjugate
- Hepatis B (HepB)
- Acellular pertussis (aP)
Org:
- Meningococcus
- Haemophilus influenzae type b (Hib)
- Pneumococcus
Conjugate subunit Vaccines
Tuberculosis
At birth, 0.05ml, ID, Right deltoid region (arm)
Live, attenuated bacteria
Freeze-dried, reconstituted w/ special diluent
BCG (Bacillus Calmette Guerin)
Diphtheria, Pertussis, Tetanus, Hepatitis B, Pneumonia, Meningitis
6, 10, 14 weeks, 0.5ml, IM, Anterolateral thigh muscle (Vastus Lateralis)
D - weakened vaccine
P - killed bacteria
T - weakened toxins
Diphtheria toxoid, inactivated pertussis bacteria, tetanus toxoid, recombinant DNA surface antigen, and synthetic conjugate of Haemophilus influenzae B bacilli
Liquid, clear
Pentavalent vaccine
DPT -HepB-Hib
(PENTAVALENT)
5-in-1 vaccine
At birth, 0.5ml, IM, Anterolateral thigh muscle (Vastus Lateralis)
Plasma derived
RNA-recombinant, using Hepatitis B surface antigen (HBs Ag)
Cloudy, liquid
Hepatitis B vaccine (Monovalent)
Poliomyelitis
6, 10, 14 weeks, 2 drops, Oral, Mouth
GI mucosal immunity
Live, attenuated virus (trivalent)
Clear, pinkish liquid
Oral polio vaccine
6, 10 weeks, 1.5ml, Oral, Mouth
Live, attenuated virus
Clear, colorless liquid, in a
container with an oral applicator
Rotavirus vaccine
Weakened toxin
Clear, colorless liquid; sometimes
slightly turbid.
Tetanus toxoid
9-11 months, 0.5ml, SUBCU, Outer part of the upper arm
Live, attenuated virus
Freeze-dried, reconstituted with a special diluent
Anti-measles vaccine
(AMV1)